Bücher von Aslak Tveito

This open access text aims at giving you the simplest possible introduction to differential equations that are used in models of electrophysiology. It covers models at several spatial and temporal scales with associated numerical methods. The text demonstrates that a very limited number of fundamental techniques can be used to define numerical methods for equations ranging from ridiculously simple to extremely complex systems of partial differential equations. Every method is implemented in Matlab and the codes are freely available online. By using these codes, the reader becomes familiar with classical models of electrophysiology, like the cable equation, the monodomain model, and the bidomain model. But modern models that have just started to gain attention in the field of computational electrophysiology are also presented. If you just want to read one book, it should probably not be this one, but if you want a simple introduction to a complex field, it is worth considering the present text.

This book is about solving partial differential equations (PDEs). Such equa- tions are used to model a wide range ofphenomena in virtually all fields ofsci- ence and technology. Inthe last decade, the general availability of extremely powerful computers has shifted the focus in computational mathematics from simplified model problems to much more sophisticated models resembling in- tricate features of real life. This change challenges our knowledge in computer science and in numerical analysis. The main objective ofthe present book is to teach modern,advanced tech- niques for numerical PDE solution. The book also introduces several models arising in fields likefinance, medicine, material technology, and geology. Inor- der to read this book, you must have a basic knowledge of partial differential equations and numerical methods for solving such equations. Furthermore, some background in finite element methods is required. You do not need to know Diffpack, although this programming environment is used in examples throughout the text. Basically, this book is about models, methods, and how to implement the methods. For the implementation part it is natural for us to use Diffpack as the programming environment, because making a PDE solver in Diffpack requires little amount of programming and because Diff- pack has support for the advanced numerical methods treated in this book. Most chapters have a part on models and methods, and a part on imple- mentation and Diffpack programming. The exposition is designed such that readers can focus only on the first part, if desired.

Mathematics is playing an ever more important role in the physical and biological sciences, provoking a blurring of boundaries between scientific disciplines and a resurgence of interest in the modern as well as the cl- sical techniques of applied mathematics. This renewal of interest, both in research and teaching, has led to the establishment of the series: Texts in Applied Mathematics (TAM). The development of new courses is a natural consequence of a high level of excitement on the research frontier as newer techniques, such as numerical and symbolic computer systems, dynamical systems, and chaos mix with and reinforce the traditional methods of applied mathematics. Thus, the purpose of this textbook series is to meet the current and future needs of these advances and encourage the teaching of new courses. TAM will publish textbooks suitable for use in advanced undergraduate and beginning graduate courses, and will complement the Applied Ma- ematical Sciences (AMS) series, which will focus on advanced textbooks and research-level monographs. Preface "It is impossible to exaggerate the extent to which modern applied mathematics has been shaped and fueled by the g- eral availability of fast computers with large memories. Their impact on mathematics, both applied and pure, is comparable to the role of the telescopes in astronomy and microscopes in biology." ¿ Peter Lax, Siam Rev. Vol. 31 No. 4 Congratulations! You have chosen to study partial differential equations.

Flow of ions through voltage gatedchannels can be represented theoretically using stochastic differentialequations where the gating mechanism is represented by a Markov model. The flow through achannel can be manipulated using various drugs, and the effect of a given drugcan be reflected bychanging the Markov model.

This book describes mathematical models and numerical techniques for simulating the electrical activity in the heart. Particular focus is on efficient numerical methods for large scale simulations on both scalar and parallel computers.

The computational approach to understanding nature and technology is currently flowering in many fields such as physics, geophysics, astrophysics, chemistry, biology, and most engineering disciplines. It is our goal to teach principles and ideas that carry over from field to field.