Bücher von Gorachand Dutta

Dieses Buch befasst sich mit den Herausforderungen bei der Entwicklung einer Point-of-Care-Testplattform. Das Buch beschreibt Assays auf Basis gedruckter Chips (Lab-on-a-Chip, Lab-on-a-PCB) für den schnellen, kostengünstigen Nachweis von Biomarkern in realen Proben. Die größten Herausforderungen bei Point-of-Care-Tests sind die Implementierung komplexer Analysemethoden in kostengünstige Technologien. Dies gilt insbesondere für Länder mit einer weniger entwickelten Gesundheitsinfrastruktur. Waschfreie, Lab-on-Chip- und Lab-on-PCB-Techniken sind sehr einfach und innovativ für die Entwicklung von Point-of-Care-Geräten. Mit der Redox-Cycling-Technologie können mehrere interessante Targets gleichzeitig auf einem gedruckten Chip nachgewiesen werden. Die vorgeschlagenen Bereiche sind von Natur aus disziplinübergreifend und vereinen Fachwissen aus den Bereichen Biosensorik, Elektrochemie, Elektronik und Elektrotechnik, Gesundheitswesen und Fertigung. Dieses Buch befasst sich mit den jüngsten Fortschritten und verschiedenen Forschungsfragen im Bereich der Nanobiotechnologie-gestützten Biosensorik und sucht nach theoretischen, methodischen, etablierten und validierten empirischen Arbeiten, die sich mit diesen verschiedenen Themen befassen.

This book reviews the potential of next-generation point-of-care diagnosis in healthcare. It also discusses the printed chip-based assay (Lab-on-a-Chip, Lab-on-a-PCB) for rapid, inexpensive biomarkers detection. The book presents the development of sensory systems based on the use of nanomaterials. It examines different biosensors for medical diagnosis using surface modification strategies of transducers. It presents electrochemical concepts based on different nanobiomaterials and nanocomposites for cancer theranostics. Notably, the book examines the recent advances in wearable, cost-effective hemodynamic sensors to detect diseases at an early stage. It further explores the combination of redox cycling and electrochemical detection to develop ultrasensitive and reproducible biosensors for point-of-care testing. Finally, the book summarizes the significant challenges in the point of care diagnostics and its future opportunities in healthcare. 

This book addresses challenges for the development of a point-of-care-test platform. The book describes printed chip-based assay (Lab-on-a-Chip, Lab-on-a-PCB) for rapid, inexpensive biomarkers detection in real samples. The main challenges of point-of-care testing require implementing complex analytical methods into low-cost technologies. This is particularly true for countries with less developed healthcare infrastructure. Washing-free, Lab-on-Chip, and Lab-on-PCB techniques are very simple and innovative for point-of-care device development. The redox cycling technology detects several interesting targets at the same time on a printed chip. The proposed areas are inherently cross-disciplinary, combining expertise in biosensing, electrochemistry, electronics and electrical engineering, health care, and manufacturing. This book focuses on recent advances and different research issues in the nanobiotechnology-enabled biosensor technology and also seeks out theoretical, methodological, well-established, and validated empirical work dealing with these different topics.

This book focusses on recent advances and different research issues in the biosensor technology and also presents theoretical, methodological, well-established and validated empirical work dealing with the technology. The book addresses challenges for the development of a point-of-care test platform. The book also describes printed chip-based assay (Lab-on-a-Chip, Lab-on-a-PCB) for rapid, inexpensive, multiplex detection of disease biomarkers in real samples. It aims to overcome existing barriers for Lab-on-a-Chip commercialization (lack of cost effective mass manufacturing methods, self-contained, fully autonomous operation and user-friendliness). Different advanced techniques including electrochemical, optical, mass, colorimetric and signal amplification strategies describe early stage disease diagnosis. The book gathers scientific and technological novelties and advancements already developed or under development in the academic and research communities. It covers a vast audience from basic science to engineering and technology experts and learners.