Bücher von Jyoti Gupta

The concept that local delivery of antibiotics into the periodontal pockets achieves a greater, more potent concentration of drug than available with systemic delivery is very appealing. The amount of drug delivered often creates sulcular medication concentration exceeding the equivalent of 1mg/ml (1000ug/ml). This level is considered bactericidal for the majority of bacteria that exhibit resistance to systemically delivered concentration.

Mathematical modelling of infectious diseases is the research work that focuses on the population dynamics of infectious diseases. Here, the work starts with basics of the epidemic modelling. The models are formulated for various infectious diseases like malaria, HIV, TB, influenza, typhoid etc. Bifurcation analysis is done for each model in order to identify the most crucial parameters responsible for the disease spread. The work is carried out under the guidance of Prof. (Dr.) Nita H. Shah, Gujarat University.

Although bone grafts have shown to be efficacious for the treatment of periodontal osseous lesions. The reconstruction appears to be limited to a mean bone fill of approximately 3-4 mm irrespective of the bone graft material used. Because, the ultimate goal of periodontal therapy is to reverse the disease process & completely regenerate the periodontium, additional stimuli to enhance the regenerative process is clearly needed. Except for fresh autogenous bone, bone replacement grafts do not provide osteogenesis or osteoinduction, mostly are osteoconductive but significant decrease in clinical parameters compared to flap debridement surgery alone. Histologically, differences among bone replacement grafts is reported. Overall probing depth reduction, attachment level gain and degree of defect fill are similar for all bone replacement grafts. As there is a continuing search for new materials & new approaches for bone repair, the future of bone graft for periodontal regeneration will always be an expanding topic¿