Bücher von Mohammed Reyazuddin

Doctoral Thesis / Dissertation from the year 2012 in the subject Medicine - Neurology, Psychiatry, Addiction, grade: 10, Jawaharlal Nehru University (ALIGARH MUSLIM UNIVERSITY), course: MD PSYCHIATRY, language: English, abstract: Schizophrenia is a clinical syndrome of variable, but profoundly disruptive, psychopathology that involves cognition, emotion, perception, and other aspects of behavior. The disorder usu-ally begins before age 25, persists throughout life, and affects persons of all social classes. In the United States, the lifetime prevalence of schizophrenia is about 1 percent, which means that about 1 person in 100 will develop schizophrenia during their lifetime. The prevalence of schizophrenia in India is 2.5/1000 as reported by Ganguli in 2000 and 2.7/1000 by Reddy et al. in 1998.A growing body of evidence suggests that peripheral activities of antioxidant enzymes and lipid peroxidation are abnormal in schizophrenic subjects. Mahadik found increased lipid pe-roxidation products and altered defence system in both chronic and drug-naive first episode schizophrenics. The accumulated results indicate that oxidative stress is integral to this disease and not the result of neuroleptic treatment.