Bücher von Muhammad Abubakar

Peste des Petits Ruminants (PPR) is a highly fatal and economically devastating disease of sheep and goats. Present study was designed to have an insight into the molecular epidemiology of PPR in the country and to investigate the persistence and transmission of PPR virus using molecular tools under field conditions. Overall, disease affected all three age groups of sheep and goats but the younger animals were more severely affected with a morbidity rate of 37.19%. The results of the phylogenetic tree indicated that all Pakistani PPRV strains were clustered in lineage IV which is the most prominent and prevalent lineage of Asia. Based on serology of 19575 serum samples from sheep and goats, 27.53 percent of the samples were positive for PPR antibodies. PPR viral antigen was detected in fecal matter for one month following vaccination. In contrast the unvaccinated animals shed virus antigen in fecal material for up to two months following outbreak resolution. Keeping in view all the findings, it is indicative of PPR endemic state in the country and the role of disease persistence, production systems of small ruminants as well as animal movements are key factors.

It is very important to understand the recent advances and basic concepts of veterinary genetics to explore the possibilities for control of diseases in animals. They are also significant for enhancing animal production and reproduction. Our book Trends and Advances in Veterinary Genetics provides a concise introduction and details to the aspects of genetics relevant to animal science and production. This is the first edition of the book so it covers the introductory level of topics which are ideal for veterinary students, classroom use, and practitioners who require more guidance with genetics. The book coverage includes the following main sections: Biotechnology and Reproductive Genetics, Advances in Embryonic Genetics, Conservation and Basic Genetics, and Veterinary Genetics and Future. Each book section comprises two chapters from renowned experts from the area and gives readers a unique opportunity to explore the topic.

Pasturella multocida, isolated from natural outbreaks of fowl cholera was characterized. Maximum isolates belonged to serotype 1 (47.62%), followed by serotype 3(28.57%), 4(14.29%) and 12(9.52%). All the serotypes were found virulent for chickens while no cross protection was observed among all the P. multocida serotypes. One plain and three adjuvanted inactivated fowl cholera vaccines were prepared from the locally isolated P. multocida serotypes and their efficacy was evaluated and compared with a commercially available oil emulsified vaccine. A double dose of oil emulsified (OEV-M) and alum adsorbed vaccines (AAV) showed better and long lasting humoral antibody response and gave better (85-100%) protection against challenge as compared to plain (FIV), oil emulsified (OEV-V) and commercial oil emulsified (OEV-Com) vaccines. In field trials the birds primed with FIV and boostered either with OEV-M or AAV showed 85-100% protection against P. multocida serotypes 1, 3, 4 and 12 while the birds primed with FIV and boostered with OEV-Com gave 75-80% protection against challenge of P. multocida serotypes 1, 3 and 4, but only 30% protection against serotype 12.