Bücher von Ravikumar Kurup

Climate change leads to endosymbiotic archaeal growth. Archaea has got methanogenic archaeal selenoproteins and uses the cellular selenium reserves and depletes selenium from the human system. This leads on to decreased cholesterol synthesis. Archaea also has got cholesterol oxidase activity and uses cholesterol for its energetics. The depletion of cholesterol leads to increased production of HMG CoA reductase enzyme, the rate limiting step in cholesterol synthesis. The increased production of HMG CoA reductase leads to defective processing of the HMG CoA reductase molecule making it antigenic. The inhibition of HMG CoA reductase by antiHMG CoA reductase antibody inhibits the isoprenoid pathway and synthesis of CoQ producing mitochondrial dysfunction. This leads to increased glycolytic activity and generation of the Warburg phenotype. Endosymbiotic archaea mediated autoimmune mitochondrial dysfunction and Warburg phenotype can lead on to climate change related tropical syndromes.

Neanderthal genes have been described in the homo sapien population. The Neanderthal brain structure results in female dominance and matriarchal social patterns. The Neanderthal phenotype is due to symbiosis by actinidic archaea using cholesterol as an energy substrate. The increasing cholesterol catabolism by actinidic archaea results in depletion of cholesterol from the body. This produces inhibition of estrogen and testosterone synthesis. This results in an asexual state and androgynous behaviour. The adult onset autistic phenotypes consequent to archaeal endosymbiosis lack social skills and graces required for social contact leading to inhibition of spontaneous normal heterosexual behaviour and family life as well as interactions. There would be an over reliance or instantaneous gratification given by the internet and artificial intelligence. This leads to break down of human relations producing the world of asexual infertile population of herbivores. The adult autistic asexual digisexual phenotypes will regenerate the population by cloned cyborgs and asexual reproduction.

The endosymbiotic archaea regulates human functions and species type and depends upon the colonic archaea whose density is determined by the fibre intake. The colonic archaeal population density depends upon dietary fibre intake. Populations with low fibre intake have lesser density of colonic archaeal microflora and endosymbiotic archaea. Endosymbiotic archaea contributes to neanderthalisation of the species. Populations consuming a high saturated fat and protein diet with low fibre intake tend to get increased endosymbiotic archaeal growth and are neanderthalised. Populations with high fibre intake up to 80 g/day tend to have reduced archaeal density in the colon and reduced archaeal endosymbiosis contributing to homo sapienisation of the population. Thus fibre intake regulates the endosymbiotic archaeal density and type of human species. Thus dietary fibre deficiency can lead to civilizational diseases and emerging infections. Dietary fibre is regulatory substance for the neuronal, immune, genomic and endocrine system.

Dietary fibre can alter the colonic microflora. High fibre intake suppresses colonic archaeal growth and archaeal endosymbiosis. High fibre diet suppresses endosymbiotic archaeal growth leading onto homo sapienisation of the species. High fibre diet leads to increased generation of butyrate and HDAC inhibition leading onto expression of the HERV genes & their reintegration into the genome. HERV jumping genes contributes to the dynamicity of the genome and is important in the evolution of synaptic connectivity and the homo sapien neocortex. Low fibre diet increases colonic archaeal growth and archaeal endosymbiosis contributing to neanderthalisation of the species and the brain. Low fibre diet and reduced levels of butyrate contributes to modulation of histone acetylation & reduced generation of HERV sequences, genomic rigidity & reduced synaptic connectivity. This leads to cerebral cortical suppression & cerebellar dominance contributing to neanderthalisation of the brain and species. Neanderthalisation of the brain leads to a cerebellar cognitive affective disorder contributing to a civilization which is dominated by nationalism, anarchy, violence, paganism and anarcho-capitalism

An actinide dependent shadow biosphere of archaea and viroids in the above mentioned disease states is described. Metal actinides in beach sands have been postulated to play a role in abiogenesis. Cholesterol is the primal prebiotic molecule synthesized on actinide surfaces with all other biomolecules arising from it. A self replicating cholesterol lipid organism could be the initial life form. A cholesterol based abiogenesis is a more likely evolutionary option and the actinidic archaea and viroids would have evolved from it. The viruses, prokaryotes and eukaryotes would have evolved from the initial isoprenoid organism derived actinidic archaea. The origin of primates and humans depends on archaeal symbiosis and symbiotic evolution.

Global warming and the low level EMF pollution results in increased endosymbiotic archaeal growth. Archaea can induce stem cell conversion and neanderthalisation of the human species. The archaea catabolizes cholesterol generating digoxin which can modulate RNA editing and magnesium deficiency resulting in reverse transcriptase inhibition. The archaea can produce permanent immune activation producing resistance to viral and bacterial infection. Thus archaeal overgrowth results in retroviral resistance and generation of the Neanderthal phenotype. Endosymbiotic archaea can secrete virus like RNA and DNA particles. Archaeal secreted DNA &RNA viroids can recombine with the expressed retroviral, non-retroviral elements & other genomic segments of the human chromosome generating new RNA & DNA viruses. Endosymbiotic archaea converts the Neanderthal cells to stem cells. The stem cells are resistant to immune attack. Stem cells can serve as a reservoir for this new RNA &DNA viruses. The homo sapiens do not have the Neanderthal mechanisms of immune activation as their archaeal load is meagre. They serve as fodder for infection from Neanderthal generated viruses & suffer eventual extinction.

The major proportion of the world ecosystem is made up of human population. Human activities in the era of industrialization lead to global warming, accumulation of greenhouse gases and initiation of climate change. This leads to increase colonic and endosymbiotic archaeal growth generating methane which accelerates global warming which assumes a tempo of its own. The human diet in the modern era with low dietary fibre and increased fat and protein also leads to colonic and endosymbiotic archaeal growth. This can also leads to increased human methane production by colonic and endosymbiotic archaeal growth initiating global warming without the effect of industrialization. The climate change can be induced by colonic and endosymbiotic archaeal growth consequent to behavioural nutritional change induced by low fibre intake. These effects of global warming can be reversed by reducing colonic and endosymbiotic archaeal growth by increasing dietary fibre intake.

Stress, diet, global warming and low level EMF pollution leads to endosymbiotic archaeal growth and civilizational disease. Most diseases in the modern world are in a sense consequent to environmental change related archaeal endosymbiosis and are treatable only to a limited extend. This forms the basic biology of medical nihilism and the limits of human capability in medical interventions. Gentle medicine encourages a moderate form of therapeutic conservatism and deals with modulating stress, diet and life styles to treat civilizational diseases like metabolic syndrome x, schizophrenia, autism, neurodegeneration, autoimmunity and malignancies.

Dietary fibre alters the colonic microflora. High fibre diet suppresses endosymbiotic archaeal growth leading onto homo sapienisation of the species. High fibre diet leads to increased generation of butyrate and HDAC inhibition leading onto expression of the HERV genes & their reintegration into the genome. The HERV jumping genes contributes to the dynamicity of the genome & is important in the evolution of synaptic connectivity & the homo sapien neocortex. Low fibre diet increases colonic archaeal growth & archaeal endosymbiosis contributing to neanderthalisation of the species & the brain. A low fibre diet and reduced levels of butyrate contributes to modulation of histone acetylation and reduced generation of HERV sequences. This contributes to rigidity of the genome and reduced synaptic connectivity. This leads to cerebral cortical suppression and cerebellar dominance contributing to neanderthalisation of the brain and the neanderthalic cerebellar cognitive affective disorder. Homo sapien brain is a cerebral cortical dominant brain & is logical as well as rational. Thus fibre intake in the diet alters symbiotic microflora especially archaeal endosymbiosis & brain function.

Stress, diet, global warming and low level EMF pollution leads to endosymbiotic archaeal growth and civilizational disease. Modern civilization results in changes in dietary habits leading to less consumption of fibre, stress and exposure to low level of EMF. This leads to increased colonic archaeal growth and archaeal endosymbiosis.Most diseases in the modern world are in a sense consequent to environmental change related archaeal endosymbiosis and are treatable only to a limited extend. This forms the basic biology of medical nihilism and the limits of human capability in medical interventions.

Climate change and low level EMF mediated endosymbiotic archaeal growth leads to frontal cortical atrophy and cerebellar dominance leading to an irrational, surreal, illogical, unreal world. This results from the endosymbiotic archaea mediated cerebellar cognitive affective disorder and adult onset epidemic robotic autistic brain. Post-truth politics is a political culture in which debate is framed largely by appeals to emotion disconnected from the details of policy. Each person¿s truth is his own subconscious impulsive perception and he spreads into society by meme replicators. This is a reflection of the climate change mediated endosymbiotic archaea induced cerebellar cognitive affective disorder.

Archaeal endosymbiosis leads to a new phenotype with neanderthalic features. The neoneanderthalic archaeaons have got magnetite capable of magnetoperception and quantal perception. The quantal perception of low level of EMF leads to frontal atrophy and cerebellar dominance producing a new neuronal phenotype with features of endemic cerebellar cognitive affective disorder manifesting as epidemic autism. This forms a new autistic behavioural phenotype which is introverted, non-compassionate, non-empathic, psychopathic and with extrasensory perceptual abilities of telepathy, telekinesis and time travel leading to communication with other galactic civilizations. The new behavioural autistic robotic neoneanderthalic phenotype will have the necessary intelligence and mental abilities cope with climate change. The neoneanderthalic archaeaons are capable of quantal perception and can communicate quantally with other star systems and multiverses. This leads on to the evolution of a galactic civilization. The neoneanderthalic archaeaons produce a metabolic phenotype capable of surviving in extremophilic environments of other star systems and can survive as civilization in other stars.

The archaeal magnetite and porphyrions can mediate quantal and its extrasensory perception. The gravitational and anti-gravitational waves or thought fields are structured in the brain by the reticular formation porphyrion network. The anti-gravitational waves can be thought of as the collective unconscious. The gravitational waves can thus function as a thought field or sub-quantal field on which the particles like neutrons, electrons, bosons, quarks, fermions can pop in and out from waves to particles. The thought field of gravity functions as the universal observer and brings the particulate world of matter into existence. Gravitational waves can form pressure waves which can create gravitational sounds. These thought sounds can undergo soni-luminescence creating photons and electromagnetic radiation the basis of the world of matter. Thus the thought field of gravity and the matter is unified. Thought conscious and unconscious underlies the world of matter.

Endosymbiotic archaea can modulate metabolism at multiple levels producing the human metabolic adaptation syndrome. Archaeal endosymbiosis leads to a metabolic adaptation syndrome consisting of pyruvate dehydrogenase deficiency, mitochondrial dysfunction, porphyria, hyperammonemia, hyperhomocysteinemia, defective protein glycosylation, cholesterol depletion, hyperprolinemia, neutral amino acid transport defect, branched chain ketoacid dehyrogenase deficiency, hyperdigoxinemia, magnesium depletion and selenium deficiency. The archaea induced cholesterol catabolism leads to low vitamin D synthesis and the endosymbiosis induced redox stress produces hypoascorbemia. The archaea induced cholesterol catabolism produces decreased sex hormone synthesis and metabolic hypogonadism. The endosymbiotic archaea mediated human adaptation syndrome can thus be treated by a high fibre - high medium chain triglyceride ketogenic diet and megavitamin therapy. This archaeal endosymbiosis induced human adaptation syndrome can lead to diseases like autoimmune disease, neuropsychiatric disorders, neurodegeneration, metabolic syndrome and oncogenesis.

Nella popolazione di homo sapiens sono stati descritti geni neandertaliani. La struttura cerebrale neandertaliana determina una dominanza femminile e modelli sociali matriarcali. Il fenotipo Neanderthal è dovuto alla simbiosi con gli archei attinici che utilizzano il colesterolo come substrato energetico. L'aumento del catabolismo del colesterolo da parte degli archei attinici provoca l'esaurimento del colesterolo dall'organismo. Questo produce l'inibizione della sintesi di estrogeni e testosterone. Ne consegue uno stato asessuato e un comportamento androgino. I fenotipi autistici ad insorgenza adulta conseguenti all'endosimbiosi arcaica mancano delle abilità sociali e delle grazie necessarie per il contatto sociale, con conseguente inibizione del normale comportamento eterosessuale spontaneo, della vita familiare e delle interazioni. Ci sarebbe un'eccessiva dipendenza o gratificazione istantanea data da Internet e dall'intelligenza artificiale. Questo porta alla rottura delle relazioni umane, producendo un mondo di popolazione asessuata e sterile di erbivori. I fenotipi adulti autistici asessuali e digisessuali rigenereranno la popolazione grazie a cyborg clonati e alla riproduzione asessuata.

Des gènes néandertaliens ont été décrits dans la population homo sapiens. La structure cérébrale de Neandertal entraîne une dominance féminine et des modèles sociaux matriarcaux. Le phénotype néandertalien est dû à la symbiose entre des archées actinidiques utilisant le cholestérol comme substrat énergétique. L'augmentation du catabolisme du cholestérol par les archées actinidiques entraîne un épuisement du cholestérol dans l'organisme. Cela produit une inhibition de la synthèse des ¿strogènes et de la testostérone. Il en résulte un état asexué et un comportement androgyne. Les phénotypes autistes adultes résultant de l'endosymbiose archéenne manquent d'aptitudes sociales et de grâces requises pour le contact social, ce qui entraîne l'inhibition du comportement hétérosexuel normal spontané, de la vie familiale et des interactions. Il y aurait une dépendance excessive ou une gratification instantanée donnée par l'internet et l'intelligence artificielle. Cela conduit à la rupture des relations humaines produisant un monde de population asexuée infertile d'herbivores. Les phénotypes adultes autistes asexués digisexuels régénéreront la population par des cyborgs clonés et la reproduction asexuée.

Neandertaler-Gene sind in der Homo-sapiens-Population beschrieben worden. Die Gehirnstruktur des Neandertalers führt zu weiblicher Dominanz und matriarchalischen Gesellschaftsstrukturen. Der Neandertaler-Phänotyp ist auf die Symbiose mit aktinidischen Archaeen zurückzuführen, die Cholesterin als Energiesubstrat nutzen. Der zunehmende Cholesterinabbau durch aktinidische Archaeen führt zu einer Erschöpfung des Cholesterins im Körper. Dies führt zu einer Hemmung der Östrogen- und Testosteronsynthese. Dies führt zu einem asexuellen Zustand und androgynem Verhalten. Den autistischen Phänotypen im Erwachsenenalter, die auf die archaeische Endosymbiose zurückzuführen sind, mangelt es an sozialen Fähigkeiten und Umgangsformen, die für soziale Kontakte erforderlich sind, was zu einer Hemmung des spontanen normalen heterosexuellen Verhaltens und des Familienlebens sowie der Interaktionen führt. Das Internet und die künstliche Intelligenz sorgen für eine übermäßige Abhängigkeit oder sofortige Befriedigung. Dies führt zum Zusammenbruch menschlicher Beziehungen und zur Entstehung einer asexuellen, unfruchtbaren Population von Pflanzenfressern. Die erwachsenen autistischen, asexuellen, zweigeschlechtlichen Phänotypen werden die Bevölkerung durch geklonte Cyborgs und asexuelle Fortpflanzung regenerieren.

Se han descrito genes neandertales en la población homo sapiens. La estructura cerebral neandertal da lugar a la dominación femenina y a patrones sociales matriarcales. El fenotipo neandertal se debe a la simbiosis de las arqueas actínidas que utilizan el colesterol como sustrato energético. El aumento del catabolismo del colesterol por parte de las archaeas actínicas provoca el agotamiento del colesterol del organismo. Esto produce la inhibición de la síntesis de estrógenos y testosterona. El resultado es un estado asexual y un comportamiento andrógino. Los fenotipos autistas de inicio en la edad adulta, consecuencia de la endosimbiosis arqueal, carecen de las habilidades sociales y las gracias necesarias para el contacto social, lo que conduce a la inhibición del comportamiento heterosexual normal espontáneo y de la vida familiar, así como de las interacciones. Habría una dependencia excesiva o una gratificación instantánea proporcionada por Internet y la inteligencia artificial. Esto lleva a la ruptura de las relaciones humanas produciendo el mundo de la población asexual infértil de herbívoros. Los fenotipos autistas asexuales digisexuales adultos regenerarán la población mediante ciborgs clonados y la reproducción asexual.

Os genes de Neanderthal foram descritos na população de homo sapien. A estrutura cerebral do Neandertal resulta em dominância feminina e padrões sociais matriarcais. O fenótipo Neandertal é devido à simbiose por arquebactérias actinídicas, utilizando o colesterol como substrato energético. O catabolismo crescente do colesterol por arquebactérias actinídicas resulta no esgotamento do colesterol do corpo. Isto produz a inibição da síntese de estrogénio e testosterona. Isto resulta num estado assexuado e num comportamento andrógino. Os fenótipos autistas de início adulto resultantes da endosimose arqueal carecem de capacidades e graças sociais necessárias para o contacto social, o que leva à inibição do comportamento heterossexual normal espontâneo e da vida familiar, bem como das interacções. Haveria uma confiança excessiva ou gratificação instantânea dada pela Internet e inteligência artificial. Isto leva à ruptura das relações humanas produzindo o mundo da população assexuada infértil de herbívoros. Os fenótipos adultos asexuais digisexuais asexuais irão regenerar a população através de ciborgues clonados e reprodução assexual.