Bücher von Tentu Nageswara Rao

Al giorno d'oggi la popolazione di pazienti diabetici è aumentata e crea una sfida ai ricercatori per lo sviluppo di una molecola priva di effetti collaterali, specialmente per il trattamento dei pazienti diabetici di tipo 2. Per questo motivo, le ricerche hanno posto particolare interesse nei confronti dei farmaci vegetali privi di effetti collaterali. Gli studi botanici hanno rivelato che la pianta Murrayakoenigii è stata utilizzata per diverse proprietà terapeutiche come anti-ulcera, analgesica, anti-microbica, anti-fungina, carminativa, stomachica. Lo scopo del presente studio è stato quello di valutare l'attività ipoglicemizzante dell'estratto etanolico del fusto di Murrayakoenigii in ratti albini indotti da alloxan, coinvolgendo un possibile meccanismo antiossidante.

En la actualidad, la población de pacientes diabéticos ha aumentado, lo que plantea a los investigadores el reto de desarrollar una molécula sin efectos secundarios, especialmente para el tratamiento de los pacientes diabéticos de tipo 2. Por ello, los investigadores han prestado especial interés a los medicamentos a base de plantas sin efectos secundarios. Por ello, los investigadores han prestado especial interés a los medicamentos a base de plantas que no tienen efectos secundarios. Los estudios botánicos han revelado que la planta Murrayakoenigii se ha utilizado con diversas propiedades terapéuticas, como antiulcerosa, analgésica, antimicrobiana, antifúngica, carminativa y estomacal. El objetivo del presente estudio era evaluar la actividad hipoglucemiante del extracto etanólico del tallo de Murrayakoenigii en ratas albinas inducidas por alloxan, implicando un posible mecanismo antioxidante.

V nastoqschee wremq populqciq bol'nyh saharnym diabetom uwelichilas', chto stawit pered issledowatelqmi zadachu razrabotki molekuly, lishennoj pobochnyh äffektow, osobenno dlq lecheniq pacientow s saharnym diabetom 2-go tipa. Poätomu issledowateli proqwlqüt osobyj interes k rastitel'nym preparatam, ne imeüschim pobochnyh äffektow. Botanicheskie issledowaniq pokazali, chto rastenie Murrayakoenigii obladaet razlichnymi terapewticheskimi swojstwami, takimi kak protiwoqzwennoe, anal'geticheskoe, antimikrobnoe, protiwogribkowoe, wetrogonnoe, zheludochnoe. Cel'ü nastoqschego issledowaniq byla ocenka gipoglikemicheskoj aktiwnosti ätanol'nogo äxtrakta steblq Murrayakoenigii u krys-al'binosow, inducirowannyh alloxanom, s ispol'zowaniem wozmozhnogo antioxidantnogo mehanizma.

De nos jours, la population de patients diabétiques a augmenté et pose des défis aux chercheurs pour développer une molécule dépourvue d'effets secondaires, en particulier pour le traitement des patients diabétiques de type 2. Les chercheurs ont donc porté un intérêt particulier aux médicaments à base de plantes qui sont dépourvus d'effets secondaires. Les études botaniques ont révélé que la plante Murrayakoenigii a été utilisée pour diverses propriétés thérapeutiques telles que l'anti-ulcère, l'analgésique, l'antimicrobien, l'antifongique, le carminatif et l'stomachique. Le but de cette étude était d'évaluer l'activité hypoglycémique de l'extrait éthanolique de la tige de Murrayakoenigii chez les rats albinos induits par l'alloxan, en impliquant un mécanisme antioxydant possible.

Atualmente, a população de doentes diabéticos aumentou e cria desafios aos investigadores para desenvolverem uma molécula sem efeitos secundários, especialmente para o tratamento de doentes diabéticos de tipo 2. Por isso, os investigadores têm-se interessado especialmente por medicamentos à base de plantas que não tenham efeitos secundários. Os estudos botânicos revelaram que a planta Murrayakoenigii tem sido utilizada em várias propriedades terapêuticas, tais como anti-úlcera, analgésica, anti-microbiana, anti-fúngica, carminativa e estomacal. O objetivo do presente estudo foi avaliar a atividade hipoglicemiante do extrato etanólico do caule de Murrayakoenigii em ratos albinos induzidos por aloxano, envolvendo um possível mecanismo antioxidante.

Heutzutage nimmt die Zahl der Diabetiker zu und stellt die Forscher vor die Herausforderung, ein Molekül ohne Nebenwirkungen zu entwickeln, insbesondere für die Behandlung von Typ-2-Diabetikern. Daher haben die Forscher besonderes Interesse an pflanzlichen Arzneimitteln gezeigt, die frei von Nebenwirkungen sind. Die botanischen Studien haben gezeigt, dass die Pflanze Murrayakoenigii in verschiedenen therapeutischen Eigenschaften wie Anti-Ulkus, analgetisch, antimikrobiell, antimykotisch, karminativ und magenstärkend verwendet wird. Das Ziel der vorliegenden Studie war es, die hypoglykämische Aktivität des ethanolischen Extrakts aus dem Stamm von Murrayakoenigii bei Alloxan-induzierten Albinoratten zu bewerten, wobei ein möglicher antioxidativer Mechanismus einbezogen wurde.

The pyrimidine moiety is one of the most widespread heterocycles in biologically occurring compounds, such as nucleic acids components (uracil, thymine and cytosine) and vitamin B1. Due to its prebiotic nature to living cells in biodiversity, it is an highly privileged motif for the development of molecules of biological and pharmaceutical interest. This present work deals with the exploration of chemistry and medicinal diversity of pyrimidine which might pave way to long await discovery in therapeutic medicine for future drug design .An efficient multicomponent one pot synthesis of 1) Methyl-6-methyl-4-phenyl -2-thioxo-1, 2, 3, 4-tetrahydro pyrimidine 2) 5-acetyl-1, 2, 3, 4-Tetrahydro pyrimidine-2-thiones. 3) Synthesis and bioactivity of the derivatives of 1-(4-(heteroaryl)-6-methyl-2-thioxo-1,2,3,4-tetrahydropyrimidin-5-yl)ethanone. The synthesis is based on the reaction of readily available substituted aryl aldehyde, ethylacetoacetate, acetyl acetone and thiourea, followed by Methanesulphonic acid catalysed dehydration. The products are obtained in good yield under mild, solvent cum catalysed conditions.

The problem of water pollution has been an environmental concern for many years numerous researchers are looking for an effective method to solve this issue. Heterogeneous photocatalysis, using a semiconductor as a catalyst, is a promising method for the destruction of water polluting pesticides This method has been called the Advanced Oxidation Process (AOP) which is one of the techniques for water treatment zinc oxide nano particles (Zno) is the most widely accepted photocatalyst because it is non-toxic, stable to photocorrosion, low cost and can potentially work using sunlight rather than artificial sources of light When zinc oxide nano particles are illuminated by UV radiation, the absorption of photons of energy is then equal to or greater than its band gap width This artifact leads to the formation of conduction-band electrons and valence-band holes on the surface of ZnO, which yield hydroxyl radicals, the primary oxidising species needed for the photocatalytic degradation of pollutants.

The analysis of pesticide residues in foods consists of sample preparation and the instrumental determination. Although the analytical instruments are developing rapidly, their detector noise, detection limits, and final quantification are usually influenced by the interferences from food matrices. Thus, the sample preparation is the bottleneck for the effective and accurate analysis of trace pesticide residues. The aim of the sample preparation is to isolate the trace amounts of analytes from a large quantity of complex matrices and eliminate the interferences from the food matrix as much as possible. Typical sample preparation steps include the sampling/homogenization, extraction, and clean-up. Among them, the extraction and clean-up steps play a critical role in the success of pesticide residue analysis.