Bücher der Reihe Advances in Biochemistry in Health and Disease

This, Volume 3 in the Springer series Advances in Biochemistry in Health and Disease, examines the contributions of signaling systems in modulating normal cardiovascular functions and how disruption of this signaling leads to cardiovascular disorders.

The main objective of Cardiac Remodeling: Molecular Mechanisms is to summarize the major research advances in molecular, biochemical and translational aspects of cardiac remodeling over the last 2 to 3 decades under one cover and touch on future directions.

This book summarizes present knowledge of different mechanisms involved in the development of positive and negative consequences of cardiac adaptation.

This book covers many aspects of atherogenesis, with particular emphasis on lipid and lipoprotein metabolism. Also explored are the roles of nuclear hormone receptors on lipid and lipoprotein metabolism and their complex roles in atherogenesis.

It analyses how mitochondria affect metabolic pathways, how they are active in the regulation of cytosolic constituents, and their role in initiating signal pathways. It gives an overview of the emergence of mitochondria as an important regulator of cell signaling, with a particular focus on their pathophysiology.

This book summarizes present knowledge of different mechanisms involved in the development of positive and negative consequences of cardiac adaptation.

The three main types of the ion pump ATPase family are: (i) P-type ATPases that transport different ions across membranes and Ca2+ATPases belongs to this catagory (ii) F-type ATPase in mitochondria, chloroplasts and bacterial plasma membranes produce ATP using the proton gradient;

Na+-K+ ATPase or Na-pump ATPase, a member of "P"-type ATPase superfamily, is characterized by association of multiple isoforms mainly of it's - and - subunits.

It analyses how mitochondria affect metabolic pathways, how they are active in the regulation of cytosolic constituents, and their role in initiating signal pathways. It gives an overview of the emergence of mitochondria as an important regulator of cell signaling, with a particular focus on their pathophysiology.