This unique publication explores diverse themes relating to thrombosis and embolism, from basic research at cell and molecular level to the actual care, prevention, and treatment of diverse categories of patients suffering from such diseases.
Nearly 30 years ago, a number of scientists working on the Enteric Nervous System (ENS) gathered at Flinders University, in Adelaide, Australia to discuss the advances and future of their research. It was a friendly and stimulating meeting, attended by most of the major players, in what was to become the discipline of 'Neurogastroenterology'.In 2014, the main Australasian Neuroscience Society meeting was held in Adelaide, Australia, providing the perfect opportunity to recreate a follow-up ENS meeting. As such, the 'ENS II 2014 meeting' aimed to identify how far the field of enteric neuroscience had developed, where the future was heading, and what technological advances had been made to address current and future unresolved questions. 30 speakers from around the world were invited to give talks and revisit the original expectations, the advances made since, and the future directions of ENS research. These discussions included three generations of investigators from 7 different countries. This publication represents the majority of proceedings from the 'The Enteric Nervous System II 2014' conference, which was held on February 1st - 2nd 2014 at the National Wine Centre of Australia, Adelaide. This meeting was an Official satellite meeting of the 34th Annual Meeting of Australasian Neuroscience Society, which was also held in Adelaide. The 20 contributions contained within this submission are from international researchers in the field of the ENS, who reviewed the advances made since the first meeting in the early 1980s and summarizes the present and future perspectives of neuro-gastroenterology. Some colleagues could not attend but did send greetings and their messages are included in these proceedings.
The BAR (Bin-Amphiphysin-Rvs) domain is a membrane lipid binding domain present in a wide variety of proteins, often proteins with a role in Rho-regulated signaling pathways.
This book addresses hot issues in the research and management of difficult-to-treat medical disorders that are commonly encountered, but for which the underlying mechanisms are often unknown.These include the adverse effects of hemodialysis and its biocompatibility in chronic kidney insufficiency, particularly related to malnutrition and inflammation, or the vulnerability of cancer patients to bacterial meningitis, the infection that remains underdiagnosed due to limited expression of symptoms. The book also covers other key topics, such as the psychological care of lung cancer patients; difficulties in the diagnosis of diffuse axonal injury in traumatic brain injury ΓÇô a disorder with a poor prognosis and high mortality rate; and the virological aspects of seasonal influenza epidemic outbreaks ΓÇô a perennial modern scourge. Further, it addresses recent developments in targeted drug delivery from titanium implants and a novel integrated thermal approach to rehabilitation of neurodegeneration-related disabilities. Featuring the latest interdisciplinary trends in biomedicine, this book connects research, theory and practice to help alleviate suffering caused by a variety of diseases.It is a resource for medical professionals, including academics, practitioners and all allied healthcare workers.
Guido Núñez-Mujica, Therese Kichuk and Cesar Carrasco-Lopez Data Analysis of Infection Rates Among Exposed Healthcare Workers Could Reveal Effective Prophylactics Against SARS-CoV-2Nihal İNANDIKLIOĞLU, Tunç AKKOÇ IMMUNE RESPONSES TO SARS-CoV, MERS-CoV AND SARS-CoV-2Mariusz Bral MD PhD, and A.M. James Shapiro MD PhD Normothermic Preservation of Liver - What does the Future Hold?Gregor Haring, Janja Zupan, Tissues from Post-Mortem Donors as Alternative Sources of Stem Cells for Regenerative MedicineÖ. Sezin SOMUNCU, H. Matthew BERNS, J. Guillermo SANCHEZ New Pioneers of Optogenetics in NeurosciencePınar Ercal, Gorke Gurel Pekozer A Current Overview of Scaffold-Based Bone Regeneration Strategies with Dental Stem CellsMahsa Ghorbaninejad, Maliheh Khademi-Shirvan, Samaneh Hosseini, Mohamadreza Baghaban Eslaminejad The Importance of Stem Cell Senescence in Regenerative MedicineZehra Narli Ozdemir Sinem Civriz Bozdag Hematological Malignancies and FertilityC. Fornaguera, C. Castells, S. Borrós Unraveling polymeric nanoparticles cell uptake pathways: two decades working to understand nanoparticles journey to improve gene therapyMotahareh Sheikh Hosseini; Peyvand Parhizkar Roudsari; Kambiz Gilany; Parisa Goodarzi; Moloud Payab; Akram Tayanloo-Beik; Bagher Larijani; Babak Arjmand Cellular Dust as a Novel Hope for Regenerative Cancer Medicine
This book includes a series of reviews on general aspects of biomarker use in the study of psychiatric and neurodegenerative diseases and the development of medications involved in their treatment. It describes the pros and cons of the various approaches and covers the successes and failures in this research field. It is only by a thorough understanding of the shortcomings that progress can be made. The overall goal is to facilitate the understanding and treatment of these disorders, by providing a viable mechanism of catching up with other areas of modern medicine, such as diabetes and heart disease. Finally, it is anticipated that the development and application of valid biomarker tests and the leveraging of novel drug targets will help the fields of psychiatry on neurodegenerative disorders move into the area of personalized medicine where the right patients can receive the right medication at the right time for the best possible outcome.
This book describes various aspects of current scientific interest in clinical developments and management of pulmonary pathologies.
Other issues pertain to quality of life, disease preventive measures, and the move toward personal health care in chronic sufferers from multiple conditions in later life. The book is addressed to researchers and practitioners, and allied health care professionals engaged in effective patient care and therapy.
This book presents original articles that report on new approaches and developments involving pulmonary disorders. Another theme tackles quality of life in chronic pathologies and the psychosocial factors, often underestimated, having influence on lung function already in adolescence, and thus liable to shape adult pulmonary morbidity.
Using both epidemiological and model organism approaches, we have gained new insights into the physiological and molecular aspects of aging, which has led to significant advancements in potential anti-aging strategies.
Being a complex disease that affects millions of people world over, cancer research has assumed great significance.
This book discusses applications of pluripotent stem cells to study eye disease in vitro and to create novel therapies for degenerative eye diseases.
The eukaryotic gene expression pathway involves a number of interlinked steps, with messenger RNA (mRNA) being the key intermediate. Although eukaryotic cells have evolved elaborate mRNA quality control mechanisms that ensure the fidelity of gene expression, some defects are not detected, thus affecting mRNA metabolism.
Cell migration plays an important role during development and in many physiological and pathological processes, from wound healing to cancer.
This edited book explores the use of technology to enable us to visualise the life sciences in a more meaningful and engaging way. It will enable those interested in visualisation techniques to gain a better understanding of the applications that can be used in visualisation, imaging and analysis, education, engagement and training.The reader will be able to explore the utilisation of technologies from a number of fields to enable an engaging and meaningful visual representation of the biomedical sciences, with a focus in this volume related to anatomy, and clinically applied scenarios.The first six chapters have an anatomical focus examining digital technologies and applications to enhance education. The first examines the history and development of ultrasound, applications in an educational setting, and as a point-of-care ultrasound at the bedside. The second chapter presents a transferable workflow methodology in creating an interactive educational and training packageto enhance understanding of the circadian rhythm. The third chapter reviews tools and technologies, which can be used to enhance off-campus learning, and the current range of visualisation technologies like virtual, augmented and mixed reality systems. Chapter four discusses how scanning methodologies like CT imagery, can make stereoscopic models. The fifth chapter describes a novel way to reconstruct 3D anatomy from imaging datasets and how to build statistical 3D shape models, described in a clinical context and applied to diagnostic disease scoring. The sixth chapter looks at interactive visualisations of atlases in the creation of a virtual resource, for providing next generation interfaces.The seventh and eight chapters discuss neurofeedback for mental health education and interactive visual data analysis (applied to irritable bowel disease) respectively.The final two chapters examine current immersive technologies ¿virtual and augmented reality, with the last chapter detailing virtual reality in patients with dementia.This book is accessible to a wide range of users from faculty and students, developers and computing experts, the wider public audience. It is hoped this will aid understanding of the variety of technologies which can be used to enhance understanding of clinical conditions using modern day methodologies.
This book is about the various roles of bioactive ceramides and other sphingolipids in cellular biology.
The cannabinoid system plays a central role in a wide variety of physiological functions that touch upon cardiovascular, gastrointestinal, immune, and nervous systems.
Most biological pathways, physical and neurological properties are highly conserved between humans and Drosophila and nearly 75% of human disease-causing genes have a functional homologue in Drosophila. This volume provides recent advances in Drosophila models for various human diseases, with each chapter providing a review of studies involving Drosophila models, as well as detailed protocols commonly used in laboratories. Starting with a review of Drosophila's value as a highly tractable model organism for studying human diseases, subsequent chapters present Drosophila models for specific human diseases. The book provides a useful resource for all scientists who are starting to use the Drosophila model in their studies, and for researchers working in the pharmaceutical industry and using new screening models to develop new medicines for various diseases.
This volume covers the science of ALDH enzymes in relation to chronic disease processes and the future therapeutic potentials of targeting ALDH in these processes.
It covers our current understanding of the HBV genome and lifecycle, liver-enriched factors in the regulation of HBV transcription and translation, HBV protein structures and biological functions, and the immunology and pathogenesis of HBV.
Numerous molecules participate in immune recognition, inhibition and activation, and these important immune molecules can be roughly divided into cell surface receptors, intracellular receptors and intracellular signaling molecules.
The book elucidates the mechanism of assembly of these materials and characterisation of their mechanical and physico-chemical properties which inspires readers not only to exploit the potential applications of nanomaterials, but also to understand their potential risks and benefits.
In addition, laboratory and clinical studies have confirmed that the chemical components of Ganoderma, such as Ganoderma lucidum polysaccharide peptides and triterpenes isolated from the fruiting body of Ganoderma lucidum, produce diverse pharmacological effects.
This book provides a comprehensive overview of the role of neuroglia in neurodegenerative diseases. In addition, to highlight the function of neuroglia in different types of neurodegenerative disease, it also discusses their mechanisms and effects on protecting or damaging neurons.
Jetzt zum Newsletter anmelden und tolle Angebote und Anregungen für Ihre nächste Lektüre erhalten.
Mit Ihrer Newsletter-Anmeldung erklären Sie sich mit unseren Datenschutzbestimmungen einverstanden.
