Bücher der Reihe Biotechnology and Bioprocessing

Details the state of yeast strain development and handling, highlighting advances in yeast selection for academic research, industry, and recombinant DNA technology.

Covers a dozen topics by presenting fundamental principles and an overview of protein biotechnology.

Offers an analysis of bioreactor design and operation and encompasses critical aspects of the biocatalytic manufacturing process. This work clarifies principles in reaction and biochemical engineering and biocell and enzyme kinetics for successful applications of biocatalysis and bioprocess technologies in the chiral drug and vitamin industries.

This volume presents the reader with an overview of current chemical sensor technology and outlines a framework relating industrial bioprocess monitoring to modern process control technology. It deals with conventional multivariable control technology, focusing on bioprocess applications.

Offers an introduction to the fundamental phenomena that govern cell adhesion and describes bioengineering processes that employ cell adhesion, focusing on biochemical and biomedical applications. This book examines industrial issues of cell adhesion - from basic concepts, quantitative experiments, and mathematical models to applications.

Presents scientific principles, empirical approaches, and practical considerations for designing industrial downstream bioprocesses for various classes of biomolecules. This work provides experimental design strategies and guidelines for developing application-specific process scale bioseparations.

Presents a comprehensive overview of cell culture technology. This work covers research, principles and equipment affecting advances in the discovery of genes, host cell selection, cloning and gene amplification, bioreactor design, protein purification, optimization and scale-up, product quality and facility design.

Contributors from European and US universities and corporations review recent developments in the integration of downstream processing and bioconversion, describing their experience with many separation technologies, including some still in the experimental stage. The topics include the construction

This book summarizes the state of the art in process analytical technologies applied to various aspects of biopharmaceutical process development and manufacturing. The text summarizes regulatory perspectives, FDA/EMEA guidelines, and new expectations. In addition, it explores new technology, especially in the area of real-time monitoring for end-point control, as well as new sensor and analytical technologies. It details established and emerging measurement technologies, including future needs, and challenges that require further research. The authors also present successful industrial-scale deployment case studies and strategies from the biopharmaceutical industry and discuss future trends.

Describes the techniques and methods involved in the design, operation, preparation and containment of bioreactor systems, taking into account the interrelated effects of variables associated with both upstream and downstream stages of the design process. This work is intended for biochemical, chemical and bioprocess engineers.

This book addresses the rapidly emerging field of Knowledge Management in the pharmaceutical, medical devices and medical diagnostics industries. In particular, it explores the role that Knowledge Management can play in ensuring the delivery of safe and effective products to patients. The book also provides good practice examples of how the effe

This book is a comprehensive guide to the design and analysis of the most advanced technologies for fuel ethanol production from feedstocks. It describes how process systems engineering can be applied to fuel ethanol production to achieve new levels of efficiency according to technical, economic, and environmental criteria. The authors cover liq

Using clear language along with numerous case studies, examples, tables, flow charts, and schematics Process Scale Bioseparations for the Biopharmaceutical Industry brings together scientific principles, empirical approaches, and practical considerations for designing industrial downstream bioprocesses for various classes of biomolecules. Experienc

This volume presents the reader with an overview of current chemical sensor technology and outlines a framework relating industrial bioprocess monitoring to modern process control technology. It deals with conventional multivariable control technology, focusing on bioprocess applications.

The fourth edition of Process Validation in Manufacturing of Biopharmaceuticals is a practical and comprehensive resource illustrating the different approaches for successful validation of biopharmaceutical processes.