Bücher der Reihe Cambridge Texts in Biomedical Engineering

An overview of medical software design, implementation and management. Covers technical, commercial and regulatory issues and includes cautionary real-world case studies. For undergraduates in biomedical engineering, electrical engineering, computer science, junior software engineers in the medical device industry, and digital health entrepreneurs.

This senior undergraduate level text describes the step-by-step design process for biomedical devices, linking sensors and signal processing to the underlying physiological signals being measured. With clinical applications included throughout, and numerous end-of-chapter problems, it provides an accessible yet in-depth introduction to the field.

This quantitative approach integrates the basic concepts of mechanics and computational modelling techniques, in a logical progression through a wide range of fundamental biomechanics principles. Online MATLAB-based software along with examples and problems using biomedical applications will motivate undergraduate biomedical engineering students to practise and test their skills.

This succinct textbook gives students the perfect introduction to the world of biomaterials, linking the fundamental properties of metals, polymers, ceramics and natural biomaterials to the unique advantages and limitations surrounding their biomedical applications. Clinical concerns such as sterilization, surface modification, cell-biomaterial interactions, drug delivery systems and tissue engineering are discussed in detail, giving students practical insight into the real-world challenges associated with biomaterials engineering; key definitions, equations and concepts are concisely summarised alongside the text, allowing students to quickly and easily identify the most important information; and bringing together elements from across the book, the final chapter discusses modern commercial implants, challenging students to consider future industrial possibilities. Concise enough to be taught in a single semester, and requiring only a basic understanding of biology, this balanced and accessible textbook is the ideal introduction to biomaterials for students of engineering and materials science.

How does one deal with a moving control volume? What is the best way to make a complex biological transport problem tractable? Which principles need to be applied to solve a given problem? How do you know if your answer makes sense? This unique resource provides over two hundred well-tested biomedical engineering problems that can be used as classroom and homework assignments, quiz material and exam questions. Questions are drawn from a range of topics, covering fluid mechanics, mass transfer and heat transfer applications. Driven by the philosophy that mastery of biotransport is learned by practice, these problems aid students in developing the key skills of determining which principles to apply and how to apply them. Each chapter starts with basic problems and progresses to more difficult questions. Lists of material properties, governing equations and charts provided in the appendices make this a fully self-contained work. Solutions are provided online for instructors.

This practical guide to biosimulation provides the hands-on experience needed to devise, design and analyze simulations of biophysical processes for applications in biological and biomedical sciences. Through real-world case studies and worked examples, students will develop and apply basic operations through to advanced concepts, covering a wide range of biophysical topics including chemical kinetics and thermodynamics, transport phenomena, and cellular electrophysiology. Each chapter is built around case studies in a given application area, with simulations of real biological systems developed to analyze and interpret data. Open-ended project-based exercises are provided at the end of each chapter, and with all data and computer codes available online (www.cambridge.org/biosim) students can quickly and easily run, manipulate, explore and expand on the examples inside. This hands-on guide is ideal for use on senior undergraduate/graduate courses and also as a self-study guide for anyone who needs to develop computational models of biological systems.

Teaching mechanical and structural biomaterials concepts for successful medical implant design, this self-contained text provides a complete grounding for students and newcomers to the field. Split into three sections: Materials, Mechanics and Case Studies, it begins with a review of sterilization, biocompatibility and foreign body response before presenting the fundamental structures of synthetic biomaterials and natural tissues. Mechanical behavior of materials is then discussed in depth, covering elastic deformation, viscoelasticity and time-dependent behavior, multiaxial loading and complex stress states, yielding and failure theories, and fracture mechanics. The final section on clinical aspects of medical devices provides crucial information on FDA regulatory issues and presents case studies in four key clinical areas: orthopedics, cardiovascular devices, dentistry and soft tissue implants. Each chapter ends with a list of topical questions, making this an ideal course textbook for senior undergraduate and graduate students, and also a self-study tool for engineers, scientists and clinicians.

Organised around problem solving, this book gently introduces the reader to computational simulation of biomedical transport processes, bridging fundamental theory with real-world applications. Using this book the reader will gain a complete foundation to the subject, starting with problem simplification, implementing it in software, through to interpreting the results, validation, and optimisation. Ten case studies, focusing on emerging areas such as thermal therapy and drug delivery, with easy to follow step-by-step instructions, provide ready-to-use templates for further applications. Solution process using the commonly used tool COMSOL Multiphysics is described in detail; useful biomedical property data and correlations are included; and background theory information is given at the end of the book for easy reference. A mixture of short and extended exercises make this book a complete course package for undergraduate and beginning graduate students in biomedical and biochemical engineering curricula, as well as a self-study guide.

Chemical Biophysics provides an engineering-based approach to biochemical system analysis for graduate-level courses on systems biology, computational bioengineering and molecular biophysics. It is the first textbook to apply rigorous physical chemistry principles to mathematical and computational modeling of biochemical systems for an interdisciplinary audience. The book is structured to show the student the basic biophysical concepts before applying this theory to computational modeling and analysis, building up to advanced topics and research. Topics explored include the kinetics of nonequilibrium open biological systems, enzyme mediated reactions, metabolic networks, biological transport processes, large-scale biochemical networks and stochastic processes in biochemical systems. End-of-chapter exercises range from confidence-building calculations to computational simulation projects.

Connecting underlying theory with real-world applications, this systematic and mathematically accessible textbook explains cell functions using the engineering principles of robust devices. It is ideal for undergraduate and graduate students taking single-semester courses in cell mechanics, biophysics and cell biology.

This book presents a full spectrum of views on current approaches to modeling cell mechanics. The authors come from the biophysics, bioengineering and physical chemistry communities and each joins the discussion with a unique perspective on biological systems.

The first MATLAB-based numerical methods textbook specifically for bioengineers, including topics on hypothesis testing, plus numerous examples drawn exclusively from biomedical engineering applications. This is an ideal core text for one-semester undergraduate courses, and is also a valuable reference for anyone interested in the quantitative aspects of biology research.

Can technology solve health problems across the world? Cutting-edge biomedical engineering meets human health crises for non-science majors and biomedical engineers.

This text introduces students to a wide selection of topics in biomechanics, ranging from the mechanics of single cells to the dynamics of human movement. The text adopts an integrated approach and is supported by a wealth of illustrations and problems, making it an essential textbook for any biomechanics course.

This book presents a full spectrum of views on current approaches to modeling cell mechanics. The authors come from the biophysics, bioengineering and physical chemistry communities and each joins the discussion with a unique perspective on biological systems.