Bücher der Reihe Cancer Treatment and Research

Cancer Policy: Pharmaceutical Safety provides invaluable information on the interesting and compelling field of cancer drug safety.

While advances in both the treatment of cancer and the management of its complications have led to significant improvement in patient survival, infections remain a significant cause of morbidity and mortality in patients with neo plastic disease.

This text provides a comprehensive overview of orthopaedic oncology - the field of orthopaedic surgery that specializes in the evaluation and treatment of bone and soft tissue tumors of the musculoskeletal system.

This book discusses emerging nanotechnology-based tools that have the potential to dramatically impact cancer research, diagnostics, and treatment. This book explains how nanotechnology can exploit the size-, shape-, and composition-dependent properties of nanomaterials to provide novel tools for precision cancer medicine.

Despite tremendous recent advances in the treatment of most malignancies, there remain several critical questions for each cancer. This book lays out the current critical questions for each major malignancy and proposes approaches to gain answers to these pressing questions.

This book comprises proceedings from the Third International Conference on Advances in Nutrition and Cancer, held in Naples in May 2012. Knowledge on the relation between lifestyle, diet, and cancer is explored in a number of contributions, and the role of dietary intervention in cancer patients is discussed.

In recent decades, cytopathology has assumed an increasing role in the primary diagnosis of mass lesions owing to its ability to deliver rapid, non-invasive, and timely information.

This book reviews the significant advances in our understanding of glioma biology that have been achieved during the past decade and describes in detail the resultant new approaches to treatment. In addition, individual chapters are devoted specifically to current treatment for low-grade gliomas, anaplastic gliomas, and glioblastoma multiforme.

Readers will also find enlightening discussion of the decision algorithm for the treatment of early-stage, high-grade bladder cancer, taking into account evidence on the most advanced treatment options and the circumstances in which surgery may need to be expedited.

In this book, a group of internationally distinguished lymphoma experts provide a comprehensive review of the most important advances in the biology, diagnosis, and therapy of T cell and NK cell malignancies.

One of the most important aspects of AIDS is the loss of protective immune function in the infected host which leads to increased prevalence of opportunistic infections and cancers. This book specifically addresses viral-induced human cancers associated with AIDS and observed in the AIDS population.

Peter Angelos Numerous ethical issues arise in the care of oncology patients. Although much has been written in the last several decades on ethical issues in caring for patients, few volumes have sought to focus the exploration on ethical issues particularly relevant to the care of cancer patients.

In this book, leaders in the field explore our current understanding of thrombosis and hemostasis in cancer and address key questions on the subject.

This book presents expert opinions on a variety of key topics related to the management of breast cancer, with a focus on the implications of recent advances and research findings for clinical practice.

This book presents the latest advances in precision medicine in some of the most common cancer types, including hematological, lung and breast malignancies.

This book identifies key treatment challenges and unique care considerations in patients with head and neck cancers, providing a comprehensive guide to patient management that illustrates the critical importance of a multidisciplinary approach in achieving optimal oncological, functional, and survival outcomes.

This book addresses the biological processes relevant to the immune phenotypes of cancer and their significance for immune responsiveness, based on the premise that malignant cells manipulate their surroundings through an evolutionary process that is controlled by interactions with innate immune sensors as well as the adaptive recognition of self/non-self. Checkpoint inhibitor therapy is now an accepted new form of cancer treatment. Other immuno-oncology approaches, such as adoptive cell therapy and metabolic inhibitors, have also shown promising results for specific indications. Immune resistance is common, however, limiting the efficacy of immunotherapy in many common cancer types. The reasons for such resistance are diverse and peculiar to the immune landscapes of individual cancers, and to the treatment modality used. Accordingly, approaches to circumvent resistance need to take into account context-specific genetic, biological and environmental factors that may affect the cancer immune cycle, and which can best be understood by studying the target tissue and correlated systemic immune markers. Understanding the major requirements for the evolutionary process governing human cancer growth in the immune-competent host will guide effective therapeutic choices that are tailored to the biology of individual cancers.

In the past, pregnancy after cancer was largely unheard of. Oncofertility has emerged as an interdisciplinary field bridging biomedical and social sciences, and examining issues regarding an individual's fertility options, choice and goals in light of cancer diagnosis, treatment and survivorship.

Clinical trials remain the most important vehicle for improving the care of cancer patients. Wells, Jr., MD, Professor of Surgery, Duke University Medical Center, Durham, NC, former Director of the American College of Surgeons and Founder of the American College of Surgeons Oncology Group.

This pertinently illustrated and well referenced text serves as an up-to-date, attractive book of oncologic imaging for radiologists, oncologists, radiation therapists and others involved in oncologic care.

This book describes the molecular mechanisms of lung cancer development and progression that determine therapeutic interventions in the era of genomics, when the rapid evolution in lung cancer diagnosis and treatment necessitates critical review of new results to integrate advances into practice.

This book provides a concise overview of the state of the art in the biology and treatment of plasma cell malignancies, a heterogeneous group of diseases primarily characterized by the presence of clonal plasma cells within the bone marrow or extramedullary sites.

This book comprehensively summarizes the current state of knowledge on malignancies of the gastrointestinal tract.

This book concisely reviews important advances in radiation oncology, providing practicing radiation oncologists with a fundamental understanding of each topic and an appreciation of its significance for the future of radiation oncology.

Readers will also find enlightening discussion of the decision algorithm for the treatment of early-stage, high-grade bladder cancer, taking into account evidence on the most advanced treatment options and the circumstances in which surgery may need to be expedited.

This book presents the latest advances in precision medicine in some of the most common cancer types, including hematological, lung and breast malignancies.

In this book, leaders in the field explore our current understanding of thrombosis and hemostasis in cancer and address key questions on the subject.

, Adrenal and Endocrine Tumors in Children' is the third volume in the series, 'Cancer Treatment and Research' devoted to pediatric oncology. Like its predecessors, it is organized into two sections. The first section again deals with issues of basic research germane to the understanding of childhood malignancies. In volume 3, the scope of the first section has been broadened to include a review that is epidemiologically oriented and a second review that is psychologically oriented. In the second part, major pediatric oncology units in Japan, Australia, Europe and the Americas have been invited to report their experience with of the multiple endocrine adrenal cortical carcinomas and the presentation neoplasia syndromes in children. In addition to these institutional reports of case material, there are reviews on genetics, pathology, and a diagnostic evaluation of children. The overview chapter on adrenal cortical carcinoma includes recommendations for radiotherapy from Dr. D' Angio and for che- motherapy from Dr. Philip Schein. Individuals using these recommended therapies are encouraged to report their results to the editors. The informa- tion will then be made available to others on request. List of Contributors ACTON, Dr. Ronald, Diabetes Research Hospital, Room 817, 1808 7th Ave. South, Birmingham, AL 35233, USA. BAUM, Edward S., M.D., Division of Hematology/Oncology, Northwestern University Medical School, Children's Memorial Hospital, 2300 Child- ren's Plaza, Chicago, IL 60614, USA. BENZ, Dr. Chris c., Dept. of Medicine, Yale University School of Medicine, New Haven, CT 06510, USA.

More often than not, progress in medicine occurs incrementally. The report of an 'important' new observation is typically greeted by a mixture of excitement and skepticism. Yet the true value of the discovery may not be known for several years until it is confirmed (or refuted) by independently conducted studies. In some cases, controversy may continue to shroud a topic due to the discordant results generated by different research groups. Since the last Gynecologic Oncology volume in the Cancer Treatment and Research series, a number of new areas have emerged that shed new light on the pathogenesis, diagnosis, and treatment of gynecologic malignancies. In this volume of the Cancer Treatment and Research series, I have attempted to integrate articles that highlight some of these newest developments with chapters that provide an overview of selected areas of controversy. This volume is not meant to be an abbreviated text of gynecologic oncology but rather a collection of selected works that can provide the reader with a better perspective on the areas of change within the field. The application of molecular biology to cervical cancer has allowed us to understand more completely the roles of human papilloma viruses and cellular oncogenes in the development of cancer of the uterine cervix.