Bücher der Reihe Carbohydrate Chemistry: Proven Synthetic Methods

Carbohydrate Chemistry: Proven Synthetic Methods, Volume 5 compiles reliable protocols for the preparation of intermediates for carbohydrate synthesis or other uses in the glycosciences.

Useful in the glycosciences, this book presents reliable protocols for the preparation of synthetic carbohydrates. Featuring worldwide contributors and a well-known series editor, the text presents new or older, not easy to find protocols generally useful to those interested in synthetic carbohydrate chemistry. Having an independent checker verify the experimental portion of the text to ensure reproducibility, the Proven Synthetic Method Series brings state-of-the-art of synthetic carbohydrate chemistry at par with general organic synthesis. Methods presented include more detailed versions of protocols that have been previously published and some new methods for the synthesis of a variety of carbohydrate derivatives.

The second volume in the series Carbohydrate Chemistry: Proven Synthetic Methods, Volume 2 offers a collection of synthetic procedures valuable to the practice of synthetic carbohydrate chemistry. The series takes an important and unique approach in that all described procedures have been independently verified as reliable and reproducible. With editors and contributors who are highly respected scientists in the field, this book provides a widely useful reference for both researchers and students, exploring carbohydrate chemistry from both academic and industrial points of view.The book begins with an introductory section that offers tricks and tips collected by the series editor from many years of experience working in carbohydrate laboratories. The subsequent chapters present detailed protocols on both specific synthetic transformations and the preparation of common synthetic intermediates, with figures to aid in comprehension. Procedures are described for regioselective benzylidene ring opening reactions, oxidation reactions to provide uronic acids, stereoselective alpha-glucosylation reactions, and more. Protocols for synthetic intermediates of general utility include 3,4,6-tri-O-acetyl-d-galactal, phenyl 4,6-O-benzylidene-1-thio-╬▒-d-mannopyranoside, 1,2-anhydro-3,4,6-tri-O-benzyl-╬▓-d-mannopyranoside, and methyl N-acetylneuraminic acid, among many others.Each chapter presents in-depth experimental descriptions for the reported procedures, including reaction setup, reaction conditions, work-up procedures, and purification protocols. The chapters also provide detailed characterization of all products and intermediates as well as copies of the 1H NMR and 13C NMR of the described products and intermediates to indicate the purity of the obtained materials and to serve as a valuable reference for future practitioners.This book provides an important starting point to reliably access synthetic carbohydrate materials and as such offers a valuable resource for the synthetic organic chemistry community. Through the streamlined access of well-defined products it provides a thrust to the rapidly growing field of chemical glycobiology.

Featuring contributions from world-renowned experts and overseen by a highly respected series editor, Carbohydrate Chemistry: Proven Synthetic Methods, Volume 4 compiles reliable synthetic methods and protocols for the preparation of intermediates for carbohydrate synthesis or other uses in the glycosciences.

Volumes in the Proven Synthetic Methods Series address the concerns many chemists have regarding irreproducibility of synthetic protocols, lack of identification and characterization data for new compounds, and inflated yields reported in chemical communications-trends that have recently become a serious problem.Exploring carbohydrate chemistry from both the academic and industrial points of view, this unique resource brings together useful information into one convenient reference. The series is unique among other synthetic literature in the carbohydrate field in that, to ensure reproducibility, an independent checker has verified the experimental parts involved by repeating the protocols or using the methods.Featuring contributions from world-renowned experts and overseen by a highly respected series editor, this latest volume compiles reliable protocols for the preparation of intermediates for carbohydrate synthesis or other uses in the glycosciences.Key Features:Explains reliable and tested protocols for the preparation of intermediates for carbohydrate synthesisOffers a unique resource in glycosciences, compiling useful information in one referencePresents protocols that are of wide use to a broad range of readers in the carbohydrate field and the life sciences, including undergraduates taking carbohydrate workshopsExplores synthetic carbohydrate chemistry from both the academic and industrial points of viewGuarantees the reader a good, clean, reproducible experiment

Featuring contributions from world-renowned experts and overseen by a highly respected series editor, Carbohydrate Chemistry: Proven Synthetic Methods, Volume 4 compiles reliable synthetic methods and protocols for the preparation of intermediates for carbohydrate synthesis or other uses in the glycosciences.