Bücher der Reihe Colloquium Series on Integrated Systems Physiology: From Molecule to Function

The gastrointestinal mucosal defense system serves to minimize mucosal injury by either ingested or endogenously produced noxious substances. However, there are two situations in which the mucosal defense system is known to be ineffective and result in gastric mucosal injury: inadvertent ingestion of H. pylori. or intentional ingestion of NSAIDs.

Several physiological mechanisms act to regulate renal potassium excretion and distribution. Together they comprise an integrated control system that may be envisioned as being made up of several interacting negative feedback control mechanisms. The intent of this volume is to describe the mechanisms of potassium regulation.

The control of breathing during exercise remains the source of considerable debate. Classical schemes of the exercise hyperpnea have incorporated elements of proportional feed-back from chemoreceptor sites and feed-forward neurogenic control. However, the precise details of the control process are still not fully resolved.

Reviews the evidence supporting the concept that intrinsic cell survival programmes can be activated by a variety of mildly noxious stimuli or pharmacologic agents to confer protection against the deleterious effects of ischemia/reperfusion.