Bücher der Reihe Contemporary Clinical Neuroscience

Also discussed are the most recent developments that could lead to new drug discoveries: the role of GPCRs in mediating pain, the development of receptor-type selective drugs based on the structural plasticity of receptor activation, and the identification of natural ligands of orphan GPCRs (deorphanization) as possible drug targets.

This book provides the first presentation of the state-of-the-art in the application of modern Neuroscience research in predicting, preventing and alleviating the negative sequelae of neurodevelopmental, acquired, or neurodegenerative brain abnormalities on speech and language.

A comprehensive book that reviews advances in ocular motor research on topics of general interest, rare, specialized or unique conditions, and pertinent basic neuroscience.

Notable experts in the field of neuroimaging provide comprehensive overviews of advances in functional and structural aspects of both common and uncommon brain disorders. Functional imaging is evolving quickly but researchers and clinicians do not always have a strong understanding of the fundamental basis of the imaging techniques that they use.

The novelty of this book's approach lies in addressing the impact of neurobiological factors as well as psychological influences on brain recovery.

An interesting character of thyroid hormone deficiency is that, without thyroid hormone, the thyroid hormone receptor may act as a "repressor" of gene expression, causing more severe consequence than those of thyroid hormone receptor knockout animals.

The proposed book will act as a guide for scientists and clinicians to the unique information that MRS can provide. It will be a comprehensive overview of clinical and pre-clinical MRS applications and potential clinical utility of MRS biomarkers in degenerative brain diseases from leading experts in the field.

The authors present the most current and cutting-edge knowledge regarding the molecular basis of cerebellar development, focusing on information relevant to laboratory scientists and clinicians providing service to patients with cerebellar disorders.

Brain disorders (neurodevelopmental, neurodegenerative, and affective disorders) can be investigated, treated, and prevented using person-centered methods.

Notable experts in the field of neuroimaging provide comprehensive overviews of advances in functional and structural aspects of both common and uncommon brain disorders. Functional imaging is evolving quickly but researchers and clinicians do not always have a strong understanding of the fundamental basis of the imaging techniques that they use.

This book is a comprehensive overview of the clinical and scientific aspects of Autism from the leading experts in the field. The thorough description of these underlying causes may help researchers and clinicians find more effective treatments and therapies for the 1 in 68 American children who have been diagnosed with Autism.

A comprehensive collection of the most recent knowledge on the biological bases of various kinds of epilepsies and modern clinical approaches to their treatment.

The proposed book will act as a guide for scientists and clinicians to the unique information that MRS can provide. It will be a comprehensive overview of clinical and pre-clinical MRS applications and potential clinical utility of MRS biomarkers in degenerative brain diseases from leading experts in the field.

An interesting character of thyroid hormone deficiency is that, without thyroid hormone, the thyroid hormone receptor may act as a "repressor" of gene expression, causing more severe consequence than those of thyroid hormone receptor knockout animals.

Brain Hypoxia and Ischemia explores the various aspects of cell death and survival that are crucial for understanding the basic mechanisms underlying brain hypoxia and ischemia.

This infor- tion is supplemented by chapters on anesthesia and sleep, computational analysis of the state of anesthesia, and the clinical phenomenon of "anesthesia awareness," a topic that has recently received much public attention.

Brain Hypoxia and Ischemia explores the various aspects of cell death and survival that are crucial for understanding the basic mechanisms underlying brain hypoxia and ischemia.

This book is a comprehensive overview of the clinical and scientific aspects of Autism from the leading experts in the field. The thorough description of these underlying causes may help researchers and clinicians find more effective treatments and therapies for the 1 in 68 American children who have been diagnosed with Autism.

Comprehensive and authoritative, Neural Mechanisms of Anesthesia draws together and critically reviews all the recent research on anesthetic mechanisms, highlighting the precise routes along which these substances operate, and how this deeper understanding will lead to the design of effective drugs free ofundesirable side effects.

A comprehensive collection of the most recent knowledge on the biological bases of various kinds of epilepsies and modern clinical approaches to their treatment.

Tremor is intimately linked to the numerous interactions of the central and peripheral nervous system components tuning motor control, from the cerebral cortex up to the peripheral effectors.

The Orexin/Hypocretin System provides an overview of all the recent exciting discoveries in the field as well as new findings such as ligand replacement and gene therapies in the animal models of narcolepsy. Several contributions cover sleep and the multiple systems involved in its regulation.

Also discussed are the most recent developments that could lead to new drug discoveries: the role of GPCRs in mediating pain, the development of receptor-type selective drugs based on the structural plasticity of receptor activation, and the identification of natural ligands of orphan GPCRs (deorphanization) as possible drug targets.

In Glutamate and Addiction, world-renowned scientific experts critically review all of the evidence for the role of glutamatergic systems in opiate, stimulant, and alcohol addiction.

Kernicterus (bilirubin encephalopathy) is a highly interesting example of metabolic encephalopathy. It fills all the characteristics of a metabolic encephalopathy in that it can develop rapidly, produces signature signs and symptoms, and is amenable to successful treatment.

This work presents integrated coverage of recent advances in the molecular mechanisms of neurodegenerative diseases and describes how these mechanisms present new therapeutic targets.

In Glutamate and Addiction, world-renowned scientific experts critically review all of the evidence for the role of glutamatergic systems in opiate, stimulant, and alcohol addiction.