Bücher der Reihe Contemporary Immunology

A critical review of the classic, as wells as most recent-and quite seminal-findings concerning the phenotypic and molecular characteristics of both fetal and neonatal B and T cells, the cells that mediate antibody and cellular immune responses in newborns and infants.

This volume offers a coherent survey of both the fundamentals of cellular immunology and its emerging, central role in major areas of clinical medicine. This book should be of interest to immunologists, biochemists, cancer chemotherapists, clinical oncologists and immunopathologists.

Professor Naor and his colleagues have written a book that explores another possible reason: cancer cells are recognized by the immune system-but is it possible that the consequence of recognition is inhibition of the immune system-by suppressor T cells or macrophages?

Caroline Hebert and a panel of key experimentalists and clinical investigators comprehensively review the state-of-the-art in the chemokine field, ranging from the effects of chemokines and their receptors in retroviral infections, to their role in inflammation, angiogenesis/angiostasis, and tumor cell biology.

Leading basic and clinical investigators from around the world summarize the most recent research on the molecular and cellular origins of lupus. This pathophysiology is shown to involve a wide variety of cell types, including T cells, B cells, natural killer cells, macrophages/monocytes, and endothelial cells.

A team of expert investigators and clinical researchers comprehensively review complement's basic biology, its role in disease, methods to measure its activity, and strategies for its inhibition in patients.

Carrying on the high standards of the much praised first edition (Durum and Muegge, Cytokine Knockouts, 1998), Giamila Fantuzzi and a panel of experts have generated completely new chapters to reflect the use of many novel mouse strains and the hundreds of recent studies on cytokine physiology.

The authoritative experts writing here explore the mechanistic aspects of such autoimmune diseases as lupus, rheumatoid arthritis, diabetes, and autoimmune thyroid disease, and where possible delineate how malfunctioning immunological mechanisms can lead to clinical symptoms.

Despite the tremendous diversity of the cells of the hematopoietic system, they are all derived from common precursor cells that are generated in the fetus and persist into adult life. However, new technologies allow increasingly elegant and informative studies in mammalian systems, particularly for cells of the hematopoietic system.

Discovery of the BLyS (also known as BAFF) family of ligands and receptors has yielded a paradigm shift in our view of B-lymphocyte selection, survival, activation, and homeostasis.

Despite the tremendous diversity of the cells of the hematopoietic system, they are all derived from common precursor cells that are generated in the fetus and persist into adult life. However, new technologies allow increasingly elegant and informative studies in mammalian systems, particularly for cells of the hematopoietic system.

Caroline Hebert and a panel of key experimentalists and clinical investigators comprehensively review the state-of-the-art in the chemokine field, ranging from the effects of chemokines and their receptors in retroviral infections, to their role in inflammation, angiogenesis/angiostasis, and tumor cell biology.

Discovery of the BLyS (also known as BAFF) family of ligands and receptors has yielded a paradigm shift in our view of B-lymphocyte selection, survival, activation, and homeostasis.

A team of expert investigators and clinical researchers comprehensively review complement's basic biology, its role in disease, methods to measure its activity, and strategies for its inhibition in patients.