Bücher der Reihe Contemporary Neuroscience

Their discussion of the fundamental biology of NSCs illustrates the signaling pathways that regulate stem cell division and differentiation, and defines the methods of NSC expansion and propagation, neuromorphogenesis, the factors determining cell fate both in vitro and in situ, and the induction of self-reparative processes within the brain.

There is also increased coverage of the animal models used in the study of neuroinflammatory mechanisms, of the new imaging methods that allow the noninvasive evaluation of microglial activation in human neurodegernerative disorders, and of the role of neuroinflammation in amyloid-dependent neuronal lysis.

There is also increased coverage of the animal models used in the study of neuroinflammatory mechanisms, of the new imaging methods that allow the noninvasive evaluation of microglial activation in human neurodegernerative disorders, and of the role of neuroinflammation in amyloid-dependent neuronal lysis.

This book, covering many key aspects of autonomic nervous system maturation, was suggested by the success of a symposium on the developing autonomic nervous system held at the Spring 1982 meeting of the Federation of American Scientists for Experi- mental Biology (Federation Proceedings 1983, 42, 1609).

In Motor Activity and Movement Disorders thirteen state-of-the-art articles explicate forefront research methodologies for measuring and interpreting motor activity in animals, as well as their applications to preclinical and clinical research involving motor disorders.

A distinguished international panel of authors define our current understanding of neuronal damage after ischemia and critically review the significant recent developments and progress in cerebrovascular accident (CVA) drug trials, both in animal models and in the clinical setting.

In Neurobiology of Aggression: Understanding and Preventing Violence, leading experts in the fields of the neurobiology, neurochemistry, genetics, and behavioral and cultural aspects of aggression and violence provide a comprehensive collection of review articles on one of the most important cross-disciplinary issues of our time.

A distinguished panel of internationally recognized neuroscientists comprehensively review the involvement of and changes in glial cells both during the normal aging process and in the major disorders of old age.

Prominent experimentalists critically review the animal models widely used in developing powerful new therapies for central nervous system diseases.

A distinguished international panel of authors define our current understanding of neuronal damage after ischemia and critically review the significant recent developments and progress in cerebrovascular accident (CVA) drug trials, both in animal models and in the clinical setting.

This work reviews the progress that has been made in strategies for testing possible mechanisms for neuronal cell death resulting in an understanding of the molecular epidemiology of dementia.

Research into the processes of tolerance and sensitization has escalated at a substantial rate in recent years, presumably because of the fundamental importance of understanding the long-term, as opposed simply to the initial, acute effects of drugs.

The idea for this book has evolved from our desire to present a conceptual approach to the study of neurotransmitters in epilepsy.

This text is a treatise drawing together and critically examining the current explosion of experimental and clinical research on the metabolism, nutrition, pharmacology, toxicology, pathology, neuropsychology, and developmental neurobiology of trace elements.

Psychopharmacology may be defined as the study of the effects of drugs on behavior. Numerous excelIent texts and review articles are available that serve to outline recent progress in psychopharmacology (particularly the Handbook of Psychopharmacology series, edited by L.

Twelve review articles by leading experts critically summarize the state of knowledge concerning molecular, anatomical, physiological and behavioural aspects of NPY and its congeners.

Neurotherapeutics: Emerging Strategies reflects the complex ity of the nervous system, but the overriding message is hope for new and better drugs to treat those diseases that rob us of ourselves.

One volume in a two-part series, covering the physiological and metabolic interactions between neurons and glia across the phylogenetic groups. New insights into neuron-glia relationships result from this comparative approach.

This text covers such topics as: somatotopic organization of the striatum and its relevance to neural transplantation; evaluation of patients with Parkinson's disease; the Lund Transplant Program (Parkinson's disease and MPTP patients); and the Paris Program.

In this book, leading-edge investigators offer effective strategies to improve current antidepressive therapies and suggest molecular, biological, and genetic approaches that will lead to the development of novel antidepressants.

In Neuroprotective Signal Transduction prominent researchers and clinicians focus on how inter- and intracellular signaling mechanisms prevent the degeneration and death of neurons occurring in both acute and chronic neurodegenerative disorders.

Distinguished researchers review the latest scientific understanding of spinal cord injury (SCI), focusing on the mechanisms causing paralysis after spinal cord trauma, the molecular determinants of neural regeneration, and methods for improving damaged function.

Prominent experimentalists critically review the animal models widely used in developing powerful new therapies for central nervous system diseases.

Recent evidence, however, suggests that channels, pumps, and ionic exchangers are involved in CNS ischemia and ischemic stroke, but the potential contribution of these channels for curing stroke is far less understood than for many other normal and pathological conditions.