Bücher der Reihe Experientia Supplementum

This book provides an up-to-date overview on the biology of microsporidia, focusing on areas where significant progress has been made in recent years. In particular, our understanding of the evolutionary position and the role of genome reduction in the biology of these enigmatic intracellular pathogens is discussed. This book also offers important updates on the mechanisms used by these organisms to modify the host cell biology of mammals, insects, nematodes, and aquatic animals, as well as the mechanisms controlling infection and host specificity. Readers gain a detailed overview of the structure and function of the polar tube, the unique invasion apparatus of microsporidia, as well as the physics and dynamics of spore firing. Particular attention is given to chronic infections in mammals caused by microsporidia, as well as common immune responses.Written by an international team of authors representing the main research groups working on microsporidian biology, this book is a valuable resource for health management professionals, experienced microbiologists, and early career scientist alike who want to learn more about these fascinating parasites. The ideas and latest finding covered in this book contribute to UN Sustainable Development Goal 3: Good Health and Well-Being.  Chapter "e;Impact of Genome Reduction in Microsporidia"e; is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.

This volume contains a collection of papers presented at the Symposium on Control Problems in Industry, held on July 22-23, 1994 in San Diego. The Symposium, conducted by the Society for Industrial and Applied Math- ematics (SIAM), with the cooperation of the Institut National Recherche Informatique et Automatique (INRIA) , focused on industrial control ap- plications that have benefited from recent mathematical and technological developments. A partial list of themes featured by the Symposium is listed below. 1) Applications of Control Techniques in a) the aerospace industry, b) the automotive industry, c) the environmental science, d) manufacturing processes, e) the petroleum industry. 2) Optimal Shape Design in Aerospace Applications 3) Optimal Design of Micro-optics 4) Robust Control and H-infinity Methods The purpose of this meeting was to bring together experts from in- dustry and academia to share their experience and present new results and new trends in modern control theory, with a focus on real industrial applications. The presentations were selected primarily for the practical significance of the problem solved, though all had significant mathemati- cal components. Control theory is an interdisciplinary field which, in its broadest sense, encompasses contributions ranging from classical engineer- ing disciplines (circuit theory, automata theory, electronics, manufacturing, mechanical engineering, material science), to theoretical engineering (sys- tem theory, computer science) and various areas of mathematics such as ODE, PDE, complex analysis, function theory, algebraic and differential geometry, numerical analysis, etc.

This book provides a comprehensive overview of the genetic basis underlying endocrine diseases. Several endocrine diseases have a genetic background, and contemporary research in the field plays a crucial role in the clinical care of endocrine diseases.

This book focuses on host-pathogen interactions at the metabolic level. It explores the metabolic requirements of the infectious agents, the microbial metabolic pathways that are dedicated to circumvent host immune mechanisms as well as the molecular mechanisms by which pathogens hijack host cell metabolism for their own benefit.

This project will show the context where inflammasomes are being studied and the molecular implications in the medical and clinical contexts. Other important topic of the inflammasomes will be the development of pharmacological inhibitors in order to improve new clinical applications.

This work was compiled to serve as a convenient source that covers a number of techniques (and details of their use) in the rather large field of nanomedicine, with special attention paid to gene delivery.

AMPK has emerged as an important integrator of signals that control energy balance through the regulation of multiple biochemical pathways in eukaryotes. The contributions are written by leading experts in the field and give an extensive overview of the current knowledge of AMPK biology and the role of AMPK in health and disease.

This project will show the context where inflammasomes are being studied and the molecular implications in the medical and clinical contexts. Other important topic of the inflammasomes will be the development of pharmacological inhibitors in order to improve new clinical applications.

This book focuses on host-pathogen interactions at the metabolic level. It explores the metabolic requirements of the infectious agents, the microbial metabolic pathways that are dedicated to circumvent host immune mechanisms as well as the molecular mechanisms by which pathogens hijack host cell metabolism for their own benefit.

MicroRNAs as the endogenous mediators of RNA interference have experienced an unprecedented career in recent years, highlighting their pathogenic, diagnostic and potential therapeutic relevance.

AMPK has emerged as an important integrator of signals that control energy balance through the regulation of multiple biochemical pathways in eukaryotes. The contributions are written by leading experts in the field and give an extensive overview of the current knowledge of AMPK biology and the role of AMPK in health and disease.

This book focuses on the application of fluorescence to study motor proteins (myosins, kinesins, DNA helicases and RNA polymerases). It can be used by researchers to gain an insight into their first experiments, or by experienced researchers who are looking to expand their research to new areas.

The most specific immune response to chemicals and drugs that cause allergic contact dermatitis, respiratory disease and adverse drug reactions is the highly antigen-specific T lymphocyte response.

Galanin is a neuropeptide found both in the central and peripheral nervous system. The studies reviewed in this volume give a fairly complete overview of the spectrum of the biological actions and functions of galanin and its receptors and on possible therapeutic applications in a number of pathological conditions.

Galanin is a neuropeptide found both in the central and peripheral nervous system. The studies reviewed in this volume give a fairly complete overview of the spectrum of the biological actions and functions of galanin and its receptors and on possible therapeutic applications in a number of pathological conditions.

Matrix metalloproteinases (MMPs) are proteolytic enzymes that are involved in many physiological and pathological processes. The present book discusses the design and development of different classes of inhibitors of important classes of MMPs, such as gelatinases and collagenases.

Environmental Toxicology is the third volume of a three-volume set on molecular, clinical and environmental toxicology that offers a comprehensive and in-depth response to the increasing importance and abundance of chemicals of daily life.

Matrix metalloproteinases (MMPs) are proteolytic enzymes that are involved in many physiological and pathological processes. The present book discusses the design and development of different classes of inhibitors of important classes of MMPs, such as gelatinases and collagenases.