Bücher der Reihe History, Philosophy and Theory of the Life Sciences

This book, originally published in French, examines the philosophical debates on functions over the last forty years and proposes new ways of analysis. Pervasive throughout the life sciences, the concept of function has the air of an epistemological scandal: ascribing a function to a biological structure or process amounts to suggesting that it is explained by its effects. This book confronts the debates on function with the use of the notion in a wide range of disciplines, such as biology, psychology, and medicine. It also raises the question of whether this notion, which is as old in the history of technology as it is in the life sciences, has the same meaning in these two domains.

This book builds on recent scholarship highlighted in the edited collections, Philosophie, histoire, biologie: mélanges offerts à Jean Gayon (Merlin & Huneman, 2018) and Knowledge of Life Today (Gayon & Petit 2018/2019). While honoring the career and the thought of Jean Gayon (1949-2018), this book showcases the continued relevance of Gayon¿s interdisciplinary work and illustrates his central place in the community of historians and philosophers of the life sciences.Chapters in this book address Jean Gayon¿s intellectual trajectory from historical epistemology to the philosophy of biology, the nature and scope of his philosophical approach to the history of science, and his unique contributions to the history and epistemology of biological concepts and theories. Drawing on published and unpublished sources, the book explores some of Gayon¿s most significant contributions to the philosophy, history, and social studies of biology.

This book takes a new approach to the debate on causal pluralism in the philosophy of biology by asking how useful pluralism is instead of debating its truth.

This book explains the ethical and conceptual tensions in the use of psychopathy in different countries, including America, Canada, the UK, Croatia, Australia, and New Zealand.

This book offers to the international reader a collection of original articles of some of the most skillful historians and philosophers of biology currently working in Latin American universities. During the last decades, increasing attention has been paid in Latin America to the history and philosophy of biology, but since many local authors prefer to write in Spanish or in Portuguese, their ideas have barely crossed the boundaries of the continent. This volume aims to remedy this state of things, providing a good sample of this production to the English speaking readers, bringing together contributions from researchers working in Brazilian, Argentinean, Chilean, Colombian and Mexican universities.The stress on the regional provenance of the authors is not intended to suggest the existence of something like a Latin American history and philosophy of biology, supposedly endowed with distinctive features. On the contrary, the editors firmly believethat advances in this field can be achieved only by stimulating the integration in the international debate. Based on this assumption, the book focuses on two topics, life and evolution, and presents a selection of contributions addressing issues such as the history of the concept of life, the philosophical reflection on life manipulation and life extension, the structure and development of evolutionary theory as well as human evolution.Life and Evolution ¿ Latin American Essays on the History and Philosophy of Biology will provide the international reader with a rather complete picture of the ongoing research in the history and philosophy of biology in Latin America, offering a snapshot of this dynamic community. It will also contribute to contextualize and develop the debate concerning life and evolution, and the relation between the two phenomena.

This book offers to the international reader a collection of original articles of some of the most skillful historians and philosophers of biology currently working in Latin American universities. During the last decades, increasing attention has been paid in Latin America to the history and philosophy of biology, but since many local authors prefer to write in Spanish or in Portuguese, their ideas have barely crossed the boundaries of the continent. This volume aims to remedy this state of things, providing a good sample of this production to the English speaking readers, bringing together contributions from researchers working in Brazilian, Argentinean, Chilean, Colombian and Mexican universities.The stress on the regional provenance of the authors is not intended to suggest the existence of something like a Latin American history and philosophy of biology, supposedly endowed with distinctive features. On the contrary, the editors firmly believe that advances in this field can be achieved only by stimulating the integration in the international debate. Based on this assumption, the book focuses on two topics, life and evolution, and presents a selection of contributions addressing issues such as the history of the concept of life, the philosophical reflection on life manipulation and life extension, the structure and development of evolutionary theory as well as human evolution.Life and Evolution ¿ Latin American Essays on the History and Philosophy of Biology will provide the international reader with a rather complete picture of the ongoing research in the history and philosophy of biology in Latin America, offering a snapshot of this dynamic community. It will also contribute to contextualize and develop the debate concerning life and evolution, and the relation between the two phenomena.

Both issues unfolded against the background of a romantic national culture of Western Europe in the 19th century: Jews, primarily from Eastern Europe, began to believe these notions and soon they took the lead in the re-formulation of Jewish and Zionist existence.

This book develops a philosophical account that reveals the major characteristics that make an explanation in the life sciences reductive and distinguish them from non-reductive explanations.

This book examines important questions in evolutionary biology, including how evolutionary innovations are generated and the origin of new constructional principles and new organs. It also scrutinizes the beginning of the major evolutionary transitions.

The World Health Organization states that depression is the leading cause of disability worldwide, and predicts that by 2030 the epidemic of depression raging across the world will be the single biggest contributor to the overall burden of disease of all health conditions.

This volume presents an innovative look at early modern medicine and natural philosophy as historically interrelated developments. The individual chapters chart this interrelation in a variety of contexts, from the Humanists who drew on Hippocrates, Galen, and Aristotle to answer philosophical and medical questions, to medical debates on the limits and power of mechanism, and on to eighteenth-century controversies over medical materialism and 'atheism.'The work presented here broadens our understanding of both philosophy and medicine in this period by illustrating the ways these disciplines were in deep theoretical and methodological dialogue and by demonstrating the importance of this dialogue for understanding their history.Taken together, these papers argue that to overlook the medical context of natural philosophy and the philosophical context of medicine is to overlook fundamentally important aspects of these intellectual endeavors.

This open access book features essays written by philosophers, biologists, ecologists and conservation scientists facing the current biodiversity crisis.

Since the 1970s, the origin of cancer is being explored from the point of view of the Somatic Mutation Theory (SMT), focusing on genetic mutations and clonal expansion of somatic cells. As cancer research expanded in several directions, the dominant focus on cells remained steady, but the classes of genes and the kinds of extra-genetic factors that were shown to have causal relevance in the onset of cancer multiplied. The wild heterogeneity of cancer-related mutations and phenotypes, along with the increasing complication of models, led to an oscillation between the hectic search of 'the' few key factors that cause cancer and the discouragement in face of a seeming 'endless complexity'. To tame this complexity, cancer research started to avail itself of the tools that were being developed by Systems Biology. At the same time, anti-reductionist voices began claiming that cancer research was stuck in a sterile research paradigm. This alternative discourse even gave birth to an alternative theory: the Tissue Organization Field Theory (TOFT). A deeper philosophical analysis shows limits and possibilities of reductionist and anti-reductionist positions and of their polarization. This book demonstrates that a radical philosophical reflection is necessary to drive cancer research out of its impasses. At the very least, this will be a reflection on the assumptions of different kinds of cancer research, on the implications of what cancer research has been discovering over 40 years and more, on a view of scientific practice that is most able to make sense of the cognitive and social conflicts that are seen in the scientific community (and in its results), and, finally, on the nature of living entities with which we entertain this fascinating epistemological dance that we call scientific research. The proposed Dynamic and Relational View of carcinogenesis is a starting point in all these directions.

The emergence of systems biology raises many fascinating questions: What does it mean to take a systems approach to problems in biology?

This volume reviews examples and notions of robustness at several levels of biological organization. Contributions span from protein folding, to cell-level robustness, to organismal and developmental robustness, to sensorimotor systems, up to the robustness of ecological systems.Several chapters detail neurobiological case-studies.

In a series of papers published in the 1970s, Christopher Boorse proposed a naturalist theory of health, mainly based on a value-free concept of 'biological function', a concept of 'reference class' and the notion of 'statistical normality'.

Chapters on slavery and the self and the development of an understanding of Dualism bring this examination up to date on the latest 21st century work in the field. At the heart of this book is the matter of how we define the problem of consciousness itself: has there been any progress in our understanding of the working of mind and brain?

This volume explores the interactions between organisms and their environments and how this "entanglement" is a fundamental aspect of all life.