Bücher der Reihe Imaging in Medical Diagnosis and Therapy

Reflecting recent advances in the field, this book provides the first detailed treatment of online interventional techniques for motion compensation radiotherapy. It explains how adaptive motion intervention is imaging-intensive and relies on near real-time image acquisition and processing. With a focus on the strategy of online motion compensation, the book discusses necessary motion detection methodology, repositioning methodology, and how to interpret and respond to target movement data in real time. It covers methods of detection and correction and then offers examples. It also gives attention to the distinct problems in dose planning and delivery posed by each adaptation technology.

Adaptive Radiation Therapy (ART) offers the promise of highly individualized radiation treatment for cancer patients through customized planning and delivery. This comprehensive book, the first focused on this evolving therapy, explores ways to optimize radiation plans. This includes the use of patient-specific 3D and 4D morphological and biological information to help define targets and individualize post-treatment assessment. It brings together world-class experts who discuss technologies for the delivery of treatments across various modalities. They also review clinical examples that demonstrate modern applications of ART for various cancers.

This book is a comprehensive survey of the field of medical imaging informatics. In addition to radiology, it also addresses other specialties such as pathology, cardiology, dermatology, and surgery, which have now adopted the use of digital images. The text discusses basic imaging informatics protocols, picture archiving and communication systems, and the electronic medical record. It also details key instrumentation and data mining technologies used in medical imaging informatics, as well as practical operational issues such as procurement, maintenance, teleradiology, and ethics.

This volume explains the biophysics and theory behind many MRI techniques and gives examples of how these techniques are applied in cancer diagnosis and treatment. The first section of the book presents basic cancer biology, theoretical aspects of NMR/MRI physics, and the hardware required to form MR images. The next three sections cover image processing and characterizing tissue properties using endogenous and exogenous contrast mechanisms. The book concludes with emerging areas of MR cancer characterization, including radiation therapy planning, molecular and cellular imaging, pH imaging, and hyperpolarized MR.

An up-to-date guide to using proton and carbon ion therapy in modern cancer treatment, this book offers a balanced and critical assessment of state-of-the-art technologies, major challenges, and the future outlook of the field. It covers the physics and radiobiology basics of proton and ion beams, dosimetry methods and radiation measurements, and treatment delivery systems. The book also gives practical guidance on patient setup, target localization, and treatment planning for clinical proton and carbon ion therapy, offering detailed reports on the treatment of various cancers.

This comprehensive volume demonstrates how the unique physicochemical properties of nanoparticles lead to novel strategies for cancer treatment and detection. After an introduction to the first principles of radiation physics and radiation biology, the book discusses fabrication of nanoparticles, safety of nanoparticles, and the quantification of nanoparticle accumulation within tissues. Successive chapters highlight the computational and experimental techniques that underlie the use of nanoparticles for imaging and treating tumors. The book concludes with regulatory issues related to human use and a summary of envisioned clinical translation.

This book gives readers an in-depth look into how big data is having an impact on the clinical care of cancer patients. Basic principles are covered early on, and clinical applications become the focus thereafter. A final section introduces emerging models for cancer prevention and detection.

This book provides a complete summary of principles, instrumentation, methods, and clinical applications of 3D dosimetry in modern radiation therapy treatment. It is an essential guide for those involved in design and implementation of treatment technology and applications in advanced radiation therapy.

This first dedicated overview for beam¿s eye view (BEV) covers instrumentation, methods, and clinical use of this exciting technology, which enables real-time anatomical imaging. It highlights how the information collected is used in the clinic for treatment verification, adaptive radiotherapy, and in-treatment interventions.

This comprehensive book provides a detailed introduction to plastic scintillation dosimetry and its use in the field of radiation dosimetry. Comprised of chapters authored by leading experts in the medical physics community, the text discusses a broad range of state-of-the-art technical implementations, from point source dosimetry scaling to 3D-

The first text to focus solely on quality and safety in radiotherapy, this work encompasses not only traditional technically oriented quality assurance activities, but also general approaches regarding quality and safety. It includes contributions from experts both inside and outside the field to discuss both the processes and the people deliver