Bücher der Reihe Medical Intelligence Unit

It addresses the biogenesis of this compartment, the transport of lysosomal proteins, the role of the lysosomal membrane in lysosomal stability and transport, the function of lysosomal proteases and hydrolases, lysosomal storage disorders, and new concepts on how to treat these diseases.

Atherosclerosis, the most common disease in humans and also the main cause of death in the Western world, only develops after an intima is formed. This volume considers all aspects of intima formation based on results which had been obtained by studying three different models: - Spontaneous intima formation;

This book is about the unique ability of the heart to protect itself against the serious consequences of an abrupt reduction in blood flow to the myocardium - a phenomenon which is switched on by stress and termed myocardial preconditioning.

Experimental and clinical evidence presented in this book illustrates that antibodies expressing different specificities can be very effective in preventing or reversing established transplant rejection.

For the first time a complete review of the research work done over the past 30 years by leading investigators around the world in targeting immunosuppressants to both solid-organ and cellular transplants is available in a single volume.

Analysis of Legionella, Listeria and Mycobacterium products possessing regulatory activity toward metabolism of host cells, essentially by affecting signal transduction in eukaryotes, is performed in the second section.

This book presents essential information on the use of the immunodeficient C.B.-17 SCID/SCID mouse for studying human hematopoiesis in vivo. In the first section, in vivo development of human hematopoietic stem cells and differentiation of human T cells are described.

White cells are the least numerous of the cellular elements in blood and ratios of white cells to platelets and white cells to red cells are ap proximately 1:15 to 1:1000 respectively.

Diverse alterations of glycosylation occur in diseases such as cancer, metastasis, leukemia, inflammatory and other diseases. Disease specific glycosylation may contribute to the disease process by altering cellular functions, or may be exploited therapeutically.

New Bacterial Vaccines focuses upon unfulfilled needs for bacterial vaccines. The distinctive feature of this book is that it focuses upon new vaccines now under development by reviewing key issues for each vaccine target and new technologies being applied to developing new vaccines.

Oral Tolerance: Cellular and Molecular Basis, Clinical Aspects, and Therapeutic Potential, has been designed as a concise yet comprehensive overview of the newest fundamental and clinical advances in the field.

Chagas' disease, which results from infection with the single cell parasite Trypanosoma cruzi, is a debilitating condition that is a major problem in many parts of Latin America.

Although, Phagocytosis was first described nearly 120 year ago, we are just recently beginning to understand the molecules that phagocytic cells use to bring about this complex cell function.

Oral Tolerance: Cellular and Molecular Basis, Clinical Aspects, and Therapeutic Potential, has been designed as a concise yet comprehensive overview of the newest fundamental and clinical advances in the field.

MALT Lymphomas is a multidisciplinary book that covers all the aspects of MALT lymphomas, from the molecular biology, the aetiology and the pathology, to all the possible therapeutic approaches.

Marfan Syndrome is a hereditary disorder of connective tissue which primarily affects the cardiovascular, skeletal, and ocular systems. This book presents an overview of clinical aspects of Marfan syndrome, FBN1 mutation analysis, the biology of fibrillin and fibrillin-containing microfibrils, and the molecular pathogenesis of the Marfan syndrome.

The objective of The Posterior Intrahepatic Approach in Liver Surgery is to describe techniques, as the more routine application today of split liver, living donor transplantation has continued to teach us more about the anatomy of the liver and its applications.

The objective of The Posterior Intrahepatic Approach in Liver Surgery is to describe techniques, as the more routine application today of split liver, living donor transplantation has continued to teach us more about the anatomy of the liver and its applications.

This book provides a comprehensive, highly readable overview of our current knowledge of the molecular pathology of basal cell and squamous cell carcinomas. The book will interest researchers or clinicians interested in the carcinogenesis and biology of basal cell or squamous cell carcinomas.

In the past five years, a large number of new chemokines and chemokine receptors have been identified. Chemokines in Viral Infections is the first to provide a comprehensive write up on the various evidences available to date on the interactions between host chemokine system and viral chemokines.

c-myc was one of the very first proto oncogenes to be identified and because it normally plays pivotal roles in both cell proliferation and cell death has enticed many to investigate the molecular mechanisms by which it transforms cells.

Leading researchers describe functional analyses at the cell and molecular level, elucidating processes related to antigen presentation and the role of cytokines, and discuss perspectives for a future use of Langerhans cells and other dendritic cells in the immunotherapy of various diseases.

This book provides a comprehensive, highly readable overview of our current knowledge of the molecular pathology of basal cell and squamous cell carcinomas. The book will interest researchers or clinicians interested in the carcinogenesis and biology of basal cell or squamous cell carcinomas.