Bücher der Reihe Neuromethods

Retinal diseases are among the leading causes of irreversible visual impairment and blindness. This vital book provides an easily accessible and authoritative reference for animal models of the most common and important retinal diseases.

World-renowned researchers outline behavioral approaches used in characterizing mood and anxiety-related behaviors in mice as well as commonly used behavioral assays to assess the potential antidepressant and anxiolytic efficacy of novel compounds.

The two Animal Models in Psychiatry volumes are loosely organized by subject. The second volume deals with affective and anxiety disorders, but also includes chapters on subjects not easily classified as either psychotic, or affective, or an- ety-related, such as aggression, mental retardation, and memory disorders.

Zebrafish (Danio rerio) play an integral role in biomedical research, enabling researchers to examine physiological mechanisms and pathways relevant to human pathogenesis and its therapy.

Preclinical research related to mood and anxiety disorders relies extensively upon mouse behavioral tests and models, the use of which continues to increase as a greater number of underlying susceptibility genes are discovered, new targets for medications are identified, and clinical studies reveal novel neurobiological risk factors.

Receptor and Ion Channel Detection in the Brain provides state-of-the-art and up-to-date methodological information on molecular, neuroanatomical and functional techniques that are currently used to study neurotransmitter receptors and ion channels in the brain.

This volume provides in-depth descriptions and discussion of clinical trial designs based on novel data analysis of high-quality trials for 11 different neurological conditions in order to ultimately improve the quality of care in neurology.

This arrangement is based on what are ostensibly increasing levels of integrated activity of the nervous system and, therefore, increasing levels of behavioral integration.

This arrangement is based on what are ostensibly increasing levels of integrated activity of the nervous system and, therefore, increasing levels of behavioral integration.

As fMRI technology has provided invaluable insights into the mechanisms through which the human brain works in healthy individuals and in patients with different neurological and psychiatric conditions, the study of brain function and even the monitoring of the effects of treatment have become more effective and efficient.

Together with its companion volumes, In Vivo Neuromethods and In Vitro Neurochemical Techniques, all three cutting-edge works will prove exceptionally useful to those basic and clinical neuroscientists who want to expand the range of their current research or develop competence in complementary methods.

This volume provides comprehensive coverage of numerous "in vitro" methods regularly utilized by neuroscientists in their daily work. The methods are treated in-depth as each chapter opens by providing an overview of the method and description of its specific applications in the lab.

The field of neurotrophic factors has witnessed exp- sive growth in the past decade.

to the Animal Models Volumes This and several other volumes in the Neuromethods series will describe a number of animal models of neuropsychiatric disorders.

Part of the "Neuromethods" series, this book focuses on advances in understanding the signaling mechanisms employed by neural tissues. It provides coverage of a variety of topics and techniques, such as: single-cell imaging technology; phosphorylation of target proteins; analysis of phosphoinositides and inositol phosphates; and, others.

Likewise, three chapters in the present v- ume deal with affective disorders, with a fourth chapter on circadian rhythms that also contributes to methods for a- mal models in affective disorders.

Transcranial Magnetic Stimulation seeks to enable new and existing practitioners to learn and follow established TMS protocols.

Similar reasons exist for Volume 4 on receptor binding techniques since experimental details are provided for all types of ligand-receptor binding, including chapters on general principles, drug discovery and development, and a most useful-appendix on computer programs for Scatchard, nonlinear, and competitive d- placement analyses.

Continuing the research of the best-selling first edition, this second edition collects three more years of research in the ever-expanding study of the cell membrane.

Advances in methodologies and experimental models are pivotal to furthering our understanding of central nervous system (CNS) functions in mammals.

This Neuromethods series book surveys new genetic techniques for generating genetically encoded activity sensors used to investigate neuronal activity. Each chapter covers a specific sensor and its utilization, with key description and implementation advice.

This book provides readers with up-to-date information on the basic principles of molecular imaging and its major applications in clinical neuroscience. It includes key tips and expert guidance to ensure successful research results.

This exploration of topics from immunohistochemistry for multiple neurochemicals covers a range of vital techniques from detecting expression levels of neurochemicals, to identifying polysynaptic pathways and recognizing functional changes in vivo.

Organized in sections on Physiology and Behavior, this Neuromethods series volume explores ideas and concepts behind the methods, tools, and tricks currently being utilized to decode the secrets of the brain of the small fruit fly, drosophila melanogaster.

Divided into two convenient sections, Protein Kinase Technologies collects contributions from experts in the field examining recent methodologies and techniques generally applicable to protein kinase research as well as to individual protein kinases which require special attention in neuroscience.

Zebrafish (Danio rerio) play an integral role in biomedical research, enabling researchers to examine physiological mechanisms and pathways relevant to human pathogenesis and its therapy.