Bücher der Reihe Results and Problems in Cell Differentiation

Within the last decade of this century, a return to some of the old questions with the new approaches has put eye development back into the limelight.

Uniquely, it puts side by side cellular communication devices and signaling mechanisms in the immune and nervous systems and discusses mechanisms of interaction between the two systems, the significance of which has only recently been fully appreciated.

Since the 1980s, our knowledge of regulatory peptides and their cognate receptors has greatly increased. This text discusses various peptide receptor systems, for example CRF, somatostatin, TRH, opioid peptides and vasopressin, and strategies for uncovering new peptides are examined.

Xenopus oocytes, mammalian brain, invertebrate nervous system) in terms of RNA trafficking, RNA-targeting sequences (cis-elements) and RNA-transporting proteins (trans-factors), activity-dependent translational regulation and the significance of the cytoskeleton for neuronal function and plasticity.

Uniquely, it puts side by side cellular communication devices and signaling mechanisms in the immune and nervous systems and discusses mechanisms of interaction between the two systems, the significance of which has only recently been fully appreciated.

Shortly afterwards, the major principles of olfactory representation had been established in mammals as the one neuron/ one receptor rule and the convergence of neurons, which express the same receptor, onto individual modules in the olfactory bulb.

Despite major efforts by the scientific community over the years, our understanding of the pathogenesis or the mechanisms of injury of multiple sclerosis is still limited.

Death receptors play a central role in directing apoptosis in mammalian cells. This book explores the molecular basis of death receptor signaling and their role in cancer development.

Recent years have witnessed striking advances in research on axons at a cellular level that substantially impact our current understanding of axonal biology. This is the first complete overview on axonal biology and includes the latest advances.

This work addresses fundamental questions of biological energy transformation and conservation, focusing on processes now understood on a structural basis. The book is a rich source for specialists interested in recent developments as well as novices.

Over the last decade it has been shown that orphan G protein-coupled receptors (GPCRs) can be used as targets to discover novel neuropeptides.

The cerebral neo cortex, unique to mammals, is regarded as the prerequisite for higher cognitive function and is the structure most closely associated with the idea of the "mind" .

Stem cell research, which now offers the promise of regenerative medicine, began with the isolation and culture of mouse embryonic stem cells by Martin Evans (who received the Nobel Prize in medicine in 2007 for this achievement) and Matthew Kaufman.

Here, mitogen-activated protein kinase (MAPK) pathways, which are modules involved in the transduction of extracellular signals to intracellular targets in all eukaryotes, are examined in terms of their role in a wide variety of biological processes.

This book highlights the potential advantages of using marine invertebrates like tunicates, echinoderms, sponges and cephalopods as models in both biological and medical research.

Our understanding of the molecular mechanisms involved in mammalian brain development remains limited.

This work addresses fundamental questions of biological energy transformation and conservation, focusing on processes now understood on a structural basis. The book is a rich source for specialists interested in recent developments as well as novices.

Actin is one of the most widespread proteins in eukaryotic cells. Each section includes an historical perspective and a detailed commentary on actin protein chemistry, molecular and cell biology of actin. This book will appeal to research scientists seeking contemporary overviews of actin and its binding proteins.

Actin is one of the most widespread proteins in eukaryotic cells. Each section includes an historical perspective and a detailed commentary on actin protein chemistry, molecular and cell biology of actin.

Includes reviews of several aspects of chromatin biology. This volume covers topics such as: the structure and function of protein modules within chromatin-remodeling proteins, newly characterized histone modifications and their functional consequences, transcription and histone dynamics, and more.

Shortly afterwards, the major principles of olfactory representation had been established in mammals as the one neuron/ one receptor rule and the convergence of neurons, which express the same receptor, onto individual modules in the olfactory bulb.

Topics include fundamental advances and current problems in the development and function of the testis, an outline of clinical findings in male infertility and an overview of the role of the Y chromosome in male fertility.

This volume gives a state-of-the-art overview on macrophage functions in various invertebrate and vertebrate systems and diseases. It also covers various aspects of macrophage development and formation, behavior and response to nano- and biomaterials, the latter of which have become very important components of modern medicine. Macrophages are evolutionarily conserved phagocytotic cells. In recent years macrophages have emerged as one of the most versatile cells of immune system, which, depending on the milieu and circumstance, participate in development or inhibition of cancer, regeneration, wound healing, inflammation, organ rejection and interaction between mother and a fetus. This book will be of particular interest to researchers working in immunology, cancer research, developmental biology, or related fields.

This book summarizes early pioneering achievements in the field of human neural stem cell (hNSC) research and combines them with the latest advances in stem cell technology, including reprogramming and gene editing.

This book focuses on the intersection between cell cycle regulation and embryo development. Specific modifications of the canonical cell cycle occur throughout the whole period of development and are adapted to fulfil functions coded by the developmental program.

The concept was simple: A peptide is released from specific hormone producing cells, endocrine cells, into circulation upon stimulation of the cells.

This book highlights the potential advantages of using marine invertebrates like tunicates, echinoderms, sponges and cephalopods as models in both biological and medical research.