Bücher der Reihe Results and Problems in Cell Differentiation

Includes reviews of several aspects of chromatin biology. This volume covers topics such as: the structure and function of protein modules within chromatin-remodeling proteins, newly characterized histone modifications and their functional consequences, transcription and histone dynamics, and more.

Shortly afterwards, the major principles of olfactory representation had been established in mammals as the one neuron/ one receptor rule and the convergence of neurons, which express the same receptor, onto individual modules in the olfactory bulb.

Topics include fundamental advances and current problems in the development and function of the testis, an outline of clinical findings in male infertility and an overview of the role of the Y chromosome in male fertility.

This volume gives a state-of-the-art overview on macrophage functions in various invertebrate and vertebrate systems and diseases. It also covers various aspects of macrophage development and formation, behavior and response to nano- and biomaterials, the latter of which have become very important components of modern medicine. Macrophages are evolutionarily conserved phagocytotic cells. In recent years macrophages have emerged as one of the most versatile cells of immune system, which, depending on the milieu and circumstance, participate in development or inhibition of cancer, regeneration, wound healing, inflammation, organ rejection and interaction between mother and a fetus. This book will be of particular interest to researchers working in immunology, cancer research, developmental biology, or related fields.

This book summarizes early pioneering achievements in the field of human neural stem cell (hNSC) research and combines them with the latest advances in stem cell technology, including reprogramming and gene editing.

This book focuses on the intersection between cell cycle regulation and embryo development. Specific modifications of the canonical cell cycle occur throughout the whole period of development and are adapted to fulfil functions coded by the developmental program.

The concept was simple: A peptide is released from specific hormone producing cells, endocrine cells, into circulation upon stimulation of the cells.

This book highlights the potential advantages of using marine invertebrates like tunicates, echinoderms, sponges and cephalopods as models in both biological and medical research.

This book summarizes early pioneering achievements in the field of human neural stem cell (hNSC) research and combines them with the latest advances in stem cell technology, including reprogramming and gene editing.

Plant cells contain various types of plastid, the best known among which is the chloroplast. This pertains to extranuclear inheritance of cell organelles and, particularly important for this series, to the participation of chloroplasts as discrete and partly autonomous cell constituents in the developmental biochemistry of plants.

Addressing the regulation of the eukaryotic cell cycle, this book brings together experts to cover all aspects of the field, clearly and unambiguously, delineating what is commonly accepted in the field from the problems that remain unsolved.

Apoptosis is currently one of the fastest moving fields in biology with spectacular progress made over the past few years in delineating the molecular It is now indisputable that apoptosis mechanisms which underlie this process.

This means that we have to pay more attention to the development of male gametes, since the imprinting of the paternal genome obviously required for the early embryonic development must occur during male gamete development.

One of the oldest problems in developmental biology is the differentiation between germ line and somatic cells. In some, apparently exceptional, cases, however, such differences in the genetic material between germ line and somatic cells were discovered.

We are convinced that the study of enzyme behavior during development merits much attention, particularly if the work is carried out on a eukaryote that lends itself to genetic and developmental analysis.

REINERT In collaboration with the first authors of this volume This volume is devoted to the development of cell clones and plants from ma nipulated cells: isolated protoplasts, cell fusion bodies, and transformed cells.

In these systems, when we observe differences between different portions of a gland, or when switches of the synthetic activity occur during development, there is no question as to what we have to look for: we are directly faced with the fact of differential protein synthesis and the problem of its control.

This book highlights the potential advantages of using marine invertebrates like tunicates, echinoderms, sponges and cephalopods as models in both biological and medical research.

In that way, developmental biologists would be apprised of recent insights in cancer cell biology and the physician scientist would be updated on events in developmental biology and both would gain new understanding of the cell biology of neoplasia.

In the last decade there has been a great expansion in our knowledge of the existence, nature and functions of mammalian carbohydrate binding proteins.

It contains nine up-to-date reviews which cover various aspects of nucleocytoplasmic transport, including the structure and function of the nuclear pore complex, the role of soluble transport factors in protein and RNA transport, and the regulation of protein transport through the nuclear pore.

This book offers a comprehensive overview on the molecular basis of fragile X syndrome. It covers all models used to investigate fragile X syndrome and includes state-of-of the art approaches like epigenetics.

Uniquely, it puts side by side cellular communication devices and signaling mechanisms in the immune and nervous systems and discusses mechanisms of interaction between the two systems, the significance of which has only recently been fully appreciated.

Since the 1980s, our knowledge of regulatory peptides and their cognate receptors has greatly increased. This text discusses various peptide receptor systems, for example CRF, somatostatin, TRH, opioid peptides and vasopressin, and strategies for uncovering new peptides are examined.

Xenopus oocytes, mammalian brain, invertebrate nervous system) in terms of RNA trafficking, RNA-targeting sequences (cis-elements) and RNA-transporting proteins (trans-factors), activity-dependent translational regulation and the significance of the cytoskeleton for neuronal function and plasticity.

Uniquely, it puts side by side cellular communication devices and signaling mechanisms in the immune and nervous systems and discusses mechanisms of interaction between the two systems, the significance of which has only recently been fully appreciated.

Shortly afterwards, the major principles of olfactory representation had been established in mammals as the one neuron/ one receptor rule and the convergence of neurons, which express the same receptor, onto individual modules in the olfactory bulb.