Bücher veröffentlicht von Humana Press Inc.

In this volume, leaders in the field share a diversity of cutting-edge techniques in endocrinology. Coverage includes protocols that allow investigators at all stages of their scientific career to successfully perform these techniques.

Providing crucial information for the expanding ornamental plant industry, leading researchers in the field compile comprehensive and step-wise protocols for rapid plant multiplication and in vitro storage of major commercially viable ornamental plants.

This volume examines methods for the production and purification of helicases from different species. It also offers detailed studies of helicase activities, including NTP binding and hydrolysis, and translocation along nucleic acid substrates.

In this book, experts provide a cutting-edge view of peptide array technology, its applications, and technical issues. The book aims to serve scientists with its insights and novel solutions in peptide array technology in order to advance this vital field.

Iron Deficiency and Overload: From Biology to Clinical Medicine is an important new text that provides a timely review of the latest science concerning iron metabolism as well as practical, data-driven options to manage at-risk populations with the best accepted therapeutic nutritional interventions.

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In Bladder Cancer: Moving the Field Forward, Cheryl Lee, David Wood, and a panel of leading authorities and researchers provide a comprehensive review of the related literature, while providing insights into the obstacles of improved survival and discuss methods to advance the field of Bladder Cancer care.

Epidermal Cells: Methods and Protocols, Second Edition expands upon the popular first edition by bringing together a panel of experienced basic and clinical researchers to describe in step-by-step detail the powerful methods they have developed and optimized to analyze and manipulate epidermal cell precursors and mature epidermal cells.

This is a fundamental yet comprehensive guidebook for researchers in the field of cancer gene profiling, as well as for those individuals in the area of biomedical/translational research. It examines the world of cancer gene profiling in light of new advances.

As sites of action for drugs used to treat schizophrenia and Parkinson's disease, dopamine receptors are among the most validated drug targets for neuropsychiatric disorders.

World-renowned researchers outline behavioral approaches used in characterizing mood and anxiety-related behaviors in mice as well as commonly used behavioral assays to assess the potential antidepressant and anxiolytic efficacy of novel compounds.

In Lipidomics: Methods and Protocols, an international panel of experts present a wide variety of reviewed as well as unpublished data on isolation techniques, structural analysis, lipid rafts, lipid trafficking and profiling, biomarkers, lipid peroxidation, biostatistics applied to lipids, software tools, and bioinformatics.

Gender differences impact the pathophysiology and clinical burden of diabetes in women. Written by experts in the field, Diabetes in Women covers sex differences in cardiometabolic risk, the impact of diabetes on women's health, diabetes and pregnancy, offspring of the diabetic mother and the disease management of women with diabetes.

In this timely and authoritative book, career-long experts explore a full range of methods for bioenergy. The volume aims to provide direction and assistance to the growing cadre of researchers endeavoring to develop new sources of bioenergy.

In Lipidomics: Methods and Protocols, an international panel of experts present a wide variety of reviewed as well as unpublished data on isolation techniques, structural analysis, lipid rafts, lipid trafficking and profiling, biomarkers, lipid peroxidation, biostatistics applied to lipids, software tools, and bioinformatics.

As two of the leading causes of death worldwide, heart disease and stroke represent a clear target for genomic research aimed at deciphering the genes and cellular pathways that underlie cardiovascular disease and creating improved therapies.

Due to their importance to cell biology, DNA topology-altering enzymes, collectively DNA topoisomerases and gyrases, have been studied thoroughly from a biochemical perspective, yet the expansion of research at the molecular and cellular levels continues to show a great deal of promise.

Fundamental to the development and vital functions of organisms, the migration of motile cells due to the detection of shallow gradients of specific chemical signals in their environments, or chemotaxis, can be clearly seen as a major force in cell biology.

Now a major approach in the identification of certain gene product functions, reverse chemical genetics allows the identification of target genes to precede phenotypic changes created by specific small molecules.

Microelectronic engineering has revolutionized electronics. This book instills in the reader a working understanding of the methods underlying microengineering and the means by which such methods can be used for a range of analytical techniques.

This loss may occur through aberration in any single component involved in signal transduction pathways that orchestrate checkpoint regulation, which may manifest through either a failure to activate the checkpoint or a failure to respond to the activated checkpoint.

Chemogenomics aims toward the systematic identification of small molecules that interact with the products of the genome and modulate their biological function.

Transposable elements are used as genetic tools for dissecting the function of a specific gene and elaborating on mechanisms leading to genetic change and diversity, and the evolutionary impact of mobile DNA on the biology and evolution of organism.

Lipases are the most applied enzymes in organic synthesis due to their broad substrate acceptance and because of the availability of the molecular, biochemical, themodynamical and solvent engineering tools, which allows the optimization of lipases and lipase-catalyzed reactions.

Today, cells are commonly analyzed en masse, with thousands of cells per sample, yielding results on the average response of the cells.

In, Homology Modelling: Methods and Protocols experts in the field describe each homology modeling step from first principles, provide case studies for challenging modeling targets and describe methods for the prediction of how other molecules such as drugs can interact with the protein.

Finally, a role for che- therapy had finally become established, principally through phase III studies c- paring chemotherapy to radiation in mostly locally advanced stages III and IV that had undergone resection.

Progress in rAAV-mediated gene transfer is so robust that long-term, efficient, and regulatable transgene expression is reproducibly achieved in large animal models. This book provides a complete and comprehensive guide to this rapidly progressing field.

In Chemical Proteomics: Methods and Protocols, expert researchers in the field provide key techniques to investigate chemical proteomics focusing on analytical strategies, how probes are generated, techniques for the discovery of small molecule targets and the probing of target function, and small molecule ligand and drug discovery.