Bücher veröffentlicht von Humana Press Inc.

This Methods in Molecular Biology(t) book details methods used to study proteomics, offering lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls.

Covering the processes and potential of biosensors that can be implanted in the central nervous system for neurotransmitter detection, this book offers practical advice on technique, as well as insight on improved approaches and the advances they might bring.

This Methods in Molecular Biology(t) book explores molecular-based assays commonly used in the diagnostic hematopathology and laboratory hematology. Includes step-by-step, readily reproducible protocols, materials lists, trouble shooting tips and more.

In Cellular and Subcellular Nanotechnology: Methods and Protocols expert researchers in the field detail the most recent advances which have been made in utilizing the enormous potential of nanotechnology for probing, imaging and manipulating life on a cellular and subcellular level.

Written by leading experts in the field, chapters cover topics such as techniques to derive novel antimicrobial targets, methods of interpreting polypharmacology-based drug target networks, and molecular dynamics techniques used to compute binding energies of drugs to their target proteins, to name a few.

This important book fills a need in the developing area of Pain Medicine. It provides physicians with an up-to-date resource that details the current understanding about the basic science underlying the mechanism of action of the various CAM therapies used for pain.

This review of pancreatic development and regeneration provides a broad overview of organogenesis from the perspective of stem cell research. It is an all-encompassing guide to explore the many aspects of "regenerative therapies" for the endocrine pancreas.

In recent years, technologies used to monitor and manipulate neuronal networks at single-cell resolution have expanded rapidly. This book examines the latest techniques in the field as well as highlighting current limitations and positing future developments.

This volume will cover a series of reviews on stem cells including adult and embryonic stem cells. Speakers were invited to present these talks during the Stem Cell Symposia in fall of 2010, in Samsun, Turkey. Unique aspect of this volume is that it brings a multidisciplinary aspect of stem cells extracted from a symposium.

Research into ancient DNA began more than 25 years ago with the publication of short mitochondrial DNA sequence fragments from the quagga, an extinct relative of the zebra.

This book examines current research into the role of neuronal death in cell signaling pathways, and its role in neurodegenerative diseases, such as Alzheimer's and Parkinson's. After introducing neurodegenerative, traumatic, and ishemic disorders, the authors cover in vitro and animal systems, and cellular and molecular mechanisms.

This volume reviews the increasing importance of glycosylation to the field of virology, as well as virus replication. The chapters provide an overview of glycosylation in relation to virus infection, and the generic techniques that are used to analyze and characterize glycoproteins.

Leading drosophilists describe in step-by-step detail all the essential techniques for studying Drosophila chromosomes and suggest new avenues for scientific exploration.

Writing in a very readable style, the author reviews the basic concepts of human molecular biology, explains the principles of the most commonly used analytical methods, and discusses the molecular principles that underlie both inherited diseases and acquired genetic abnormalities that lead to cancer.

Colin Graham and a team of leading investigators and expert clinical scientists update the acclaimed first edition with a collection of powerful, up-to-date PCR-based methods for DNA sequencing, many suitable for human genome sequencing and mutation detection in human disease.

Human pluripotent stem cells such as human embryonic stem cells (hESC) and induced pluripotent stem cells (iPSC) with their unique developmental plasticity hold immense potential as cellular models for drug discovery and in regenerative medicine as a source for cell replacement.

The haemostatic system is one the most important physiological systems for maintaining health and well being, and thus the investigation of the haemostatic system remains a research priority.

This detailed volume provides in-depth protocols for protein labeling techniques and applications, with an additional focus on general background information on the design and generation of the organic molecules used for the labeling step.

This volume seeks to enable the discovery of tools in chemical biology by providing readers with various techniques ranging from initial chemical genetic screening to target identification.

In its revised second edition, this Methods in Molecular Biology(TM) book provides advanced techniques and animal models that are critical for integrated pain research. Includes materials and reagents lists, reproducible lab protocols and troubleshooting tips.

This Methods in Molecular Biology(TM) volume details methods for fabricating DNA, including techniques for the assembly of oligonucleotide, cloning of synthons into larger fragments, protocols, software and educational and biosecurity impacts of gene synthesis.

Recent advances in genetics over the last quarter of a century, especially in molecular techniques, have dramatically reduced the cost of determining genetic markers and hence opened up a field of research that is increasingly helping to detect, prevent and/or cure many diseases that afflict humans.

In its new edition, this Methods in Molecular Biology(TM) book offers protocols for preparing amyloid and its precursors, cell culture models, extraction from tissue, detection in vitro and in vivo and nontransgenic methods for developing amyloid mouse models.

The field of protein NMR spectroscopy has rapidly expanded into new areas of biochemistry, molecular biology and cell biology research that were impossible to study as recently as ten years ago.

The variability of clinical symptoms in mitochondrial diseases calls for a systematic presentation of the full range of protocols used in their assessment. This volume provides cutting-edge methods of analysis as well as expert guidance on how to apply them.

This Methods in Molecular Biology(TM) volume offers methods for investigating chromatin remodeling in vitro and in vivo, in yeast, plants and mammalian cells, and at local and global levels. Includes materials lists, protocols, troubleshooting tips and more.

Some of these cell types and various blood-derived cell lineages are involved in the repair of various types of tissue damage that span the spectrum of medical disorders.