Bücher veröffentlicht von Humana Press Inc.

A comprehensive state-of-the-art collection of the most frequently used techniques for plant cell and tissue culture.

In this book, leading researchers in the field of Bioinformatics provide a selection of the most useful and widely applicable methods, able to be applied as is, or with minor variations, to many specific problems.

This, the second volume in the series, provides a comprehensive collection of the cutting-edge methods making a major contribution to understanding the nucleus and its nanostructure today. Chapters contain tips for avoiding known pitfalls.

In Gene Therapy Protocols, Volumes 1 and 2, internationally recognized investigators describe cutting-edge laboratory techniques for the study of Production and In Vivo Applications of Gene Transfer Vectors (Volume 1) and Design and Characterization of Gene Transfer Vectors (Volume 2).

Robotic technology has paved the way for new opportunities in pediatric urologic surgery. Written by highly respected surgeons, Pediatric Robotic Urology provides a state-of-the-art, comprehensive overview of the precise surgical techniques that are changing the practice of pediatric urologic surgery.

In Bioinformatics, leading researchers in the field provide a selection of the most useful and widely applicable methods, able to be applied as is, or with minor variations, to many specific problems. Over 80 authors from around the globe have contributed.

This book sees expert researchers explore current issues and methodologies in this expanding field, addressing areas of gene discovery and functional analysis with a focus on the sub-disciplines of genetic mapping, mRNA, protein and metabolite profiling.

In this book internationally recognized investigators describe cutting-edge laboratory techniques for the study of Production and In Vivo Applications of Gene Transfer Vectors and Design and Characterization of Gene Transfer Vectors.

Volume I: Nuclei and Subnuclear Structures presents an overview of features of the intranuclear environment, followed by the most recent procedures for isolating nuclei from a wide range of cell types including muscle cells, yeast, oocytes, cells with polytene nuclei, Arabidopsis, trypanosomes, and dinoflagellates.

The second edition of this book constitutes a comprehensive manual of new techniques for setting up mammalian cell lines for production of biopharmaceuticals, and for optimizing critical parameters for cell culture considering the whole cascade from lab to final production.

In this book, leading researchers in the field of Bioinformatics provide a selection of the most useful and widely applicable methods, able to be applied as is, or with minor variations, to many specific problems.

Since the first edition, published in 2001, genomics research has taken great strides. In this updated second edition, a team of expert researchers share the most current information in a field that has recently switched emphasis from gene identification to functional genomics and the characterization of genes and gene products.

A diverse team of researchers, technologists, and engineers describe, in simple and practical language, the major current and evolving technologies for improving the biocatalytic capabilities of mammalian, microbial, and plant cells.

This collection of diverse articles by the pioneers of modern genomics takes stock of the current state of the field and elucidates the contribution that sequencing genomes has made to our understanding of microbial metabolism and evolution.

This expert volume covers an interdisciplinary and rapidly growing area of biomedical research comprising genetic, biochemical, pathological, and clinical studies aimed at the diagnosis and therapy of human diseases which are either caused by or associated with mitochondrial dysfunction.

This volume provides an overview of RNA bioinformatics methodologies, including basic strategies to predict secondary and tertiary structures, and novel algorithms based on massive RNA sequencing.

This volume is essential for geneticists, molecular biologists, biochemists, and medical doctors interested in the use of mouse models in cancer research.

In this volume expert researchers detail in silico methods widely used to study peptides. Chapters focus on integration and application of technologies to analyze, model, identify, predict, and design a wide variety of bioactive peptides, peptide analogues and peptide drugs, as well as peptide-based biomaterials.

Opioid Receptors: Methods and Protocols serves as a comprehensive guide to both key new techniques and established methods for the investigation of genetics, structural biology, transcription, and post-transcriptional events of opioid receptors.

Research into this potentially deadly agent of meningitis and septicaemia is a matter of urgency, and this volume details new methods and technologies that can be deployed to further our understanding of, and ability to tackle, neisseria meningitides.

Neurodegeneration tackles the challenges involved with neurodegenerative disorders, such as Alzheimer's and Parkinson's disease. The text presents cutting-edge analytical and technological approaches to study the mechanisms underlying neurodegenerative processes.

Despite considerable variability within the scientific community, allosteric regulation can best be defined functionally as how a macromolecule binds one ligand differently when a second ligand is or is not pre-bound to the macromolecule, which constitutes a vital aspect of protein structure/function.

In Kinase Inhibitors: Methods and Protocols, experts in kinase biology, drug discovery, and clinical research present a series of exemplary methods that can be used to address the many challenges facing scientists in the discovery and development of kinase inhibitors both for research and clinical use.

Our understanding of the molecular and cellular mechanisms that control skeletal muscle development, regeneration, and adaptive responses to activity has increased dramatically in recent years, fostered by innovative techniques and approaches that are either specifically designed or adapted for research in skeletal muscle biology.

Focusing on the two broad areas of epigenetics, DNA methylation and chromatin modifications, this book highlights select techniques that have been mainstays in the field. It also covers methods especially relevant to extant discoveries in epigenetics.

This volume organizes and collects technical advances from leaders in the field to make laboratory protocols more readily available and understandable to those who are attempting to incorporate nanotechnologic techniques into their proteomic research.

and suitable animal models for non-human clinical trials.The chapters of this book are organized into six sections: Stem Cells, Biomaterials and the Extracellular Environment, Engineered Tissue, Synthetic Organs, Immune Response, and Animal Models.

This book presents a readily reproducible collection of established and emerging techniques for neuropeptide research. Coverage includes immunocytochemical localization, biochemical characterization, development of genetic probes and functional analysis.

Preclinical research related to mood and anxiety disorders relies extensively upon mouse behavioral tests and models, the use of which continues to increase as a greater number of underlying susceptibility genes are discovered, new targets for medications are identified, and clinical studies reveal novel neurobiological risk factors.

The proteome consists of a complex mixture of proteins each of which need to be folded correctly in order to function for the health of the organism, and many of these proteins require molecular chaperones to reach the correct conformation and, in some cases, to remain in a folded form.