Bücher veröffentlicht von Humana Press Inc.

Thus, a proper understanding of the inflammatory basis may provide clues to new therap- tic targets not only in classical inflammatory diseases, but atherosclerosis, cancer, and ischemic heart disease as well.

A section on animal models of carcinogenesis presents comprehensive evidence that general NSAIDs inhibit a variety of malignant neoplasms in vivo, and highlights recent findings which show that COX-2 blocking agents produce striking chemopreventive effects against colon cancer and breast cancer as well as other malignancies.

Viral Vectors for Gene Therapy: Methods and Protocols consists of 30 ch- ters detailing the use of herpes viruses, adenoviruses, adeno-associated viruses, simple and complex retroviruses, including lentiviruses, and other virus systems for vector development and gene transfer.

With microarray technology, ordered arrays of oligonucleotides or other DNA sequences are attached or printed to the solid support using au- mated methods for array synthesis.

In vitro utilization of liposomes is now recognized as a powerful tool in many bioscience investigations and their associated clinical studies, e.g., liposomes in drug targeting;

In 1998, 1264 papers were published about cocaine and only 17 about kava kava, an abused herb that is not without toxic side effects.

Interleukins are a family of proteins that regulate the maturation, diff- entiation, or activation of cells involved in immunity and inflammation, and belong to a broader family termed cytokines.

The Nutrition and Health series has been very fortunate to have each of the volumes recognized by rating services, such as Doody's, as valuable contributions for health professionals and individuals interested in the most up-to-date and balanced information from the experts in nutrition.

These distinguished authorities critically review what is known about autonomic control of the heart, hypothalamo-pituitary- adrenal modulation, heart pain, modulation by humoral factors, and the relationship between cognitive/neuropsychiatric disorders and heart disease.

It is a pleasure to write the foreword to Nutrition and Table 1 Nutritional Status and Outcome of Infection Immunology: Principles and Practice.

What has emerged over the years is that most chemokine receptors bind several distinct ligands, and indeed the majority of chemokines are able to bind to multiple chemokine receptors, explaining to some extent the apparent disparity in the numbers of chemokines and rec- tors.

As the major task of sequencing the human genome is near completion and full complement of human genes are catalogued, attention will be focused on the ultimate goal: to understand the normal biological functions of these genes, and how alterations lead to disease states.

The discovery of Epstein-Barr virus (EBV) by Epstein, Achong, and Barr, reported in 1964 (Lancet 1:702-703), was stimulated by Denis Burkitt's rec- nition of a novel African childhood lymphoma and his postulation that an infectious agent was involved in the tumor's etiology (Nature194:232-234, 1962).

Nutrients, Dietary Supplements, and Nutriceuticals: Cost Analysis Versus Clinical Benefits provides the most current, concise, scientific appraisal and economic analysis (costs vs.

With a unique emphasis on the correlation between cytology and surgical pathology, Cytology and Surgical Pathology of Gynecologic Neoplasms provides a ready reference for both the practicing pathologist and pathologist in training in finding quick answers to their diagnostic challenges.

Hematopathology: Genomic Mechanisms of Neoplastic Diseases will keep physicians abreast of the rapid and complex changes in genomic medicine, as exemplified by the molecular pathology of hematologic malignancies.

This book fills the gaps in our understanding of the identification of triggers, recognition of clinical presentations, understanding of the natural history of these reactions, and selection of treatment strategies including those focused on cellular and molecular targets.

This volume on metabonomics provides detailed information on the procedures involved in nuclear magnetic resonance (NMR) spectroscopy, gas chromatography-mass spectrometry (GS-MS), liquid chromatography-mass spectrometry (LC-MS), and capillary electrophoresis-mass spectrometry (CE-MS).

This timely book is a road map for defining the care of acute heart failure patients in the short stay or observation unit setting.

Leading international researchers and clinicians comprehensively review in detail what is known about the ability of diet to enhance human immune function in health, disease, and under various condition of stress.

Authoritative researchers and clinicians review our latest understanding of andrology in both basic science and clinical medicine. Other chapters consider important topics such as androgens use in athletes, the potential of androgens to improve physical function and quality of life in older men, and androgens as potential male contraceptives.

This book presents timely and important tools needed to elucidate particular roles of phosphoinositides in plants. It includes easy-to-use, reproducible protocols and contains expert tips on troubleshooting and avoiding known pitfalls.

Handbook of Food Fortification and Health: From Concepts to Public Health Applications Volume 2 represents a multidisciplinary approach to food fortification.

Also discussed are how protein and peptide separation techniques are applied in proteomics, how mass spectrometry is used to identify proteins, and how data analysis software enables protein identification and the mapping of modifications.

Exploring the activation and function of components of the MAPK signaling cascades, this volume presents fully updated techniques to study MAPK. Chapters include lists of the necessary materials, step-by-step laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.

Leading experts in the use of MRI explain its basic principles and demonstrate its power to understand biological processes with numerous cutting-edge applications.