Bücher veröffentlicht von Humana Press Inc.

Probiotics in Pediatric Medicine provides clinicians a tool to understand the current evidence for the role of probiotics in various pediatric disorders related to the gastrointestinal as well as the extra-intestinal tract.

As a high throughput method for analyzing gene function, cell-based microarrays have proven to be of vital importance, allowing high throughput analysis of over expression and knock down of proteins.

Protein expression in a heterologous host is a cornerstone of biomedical research and of the biotechnology industry. For example, membrane proteins constitute a significant percentage of the total cellular proteins but as a class are very difficult to overexpress, especially in a heterologous host.

Myc controls multiple cellular functions, including cell proliferation, growth, differentiation and death, both directly and indirectly, through its modulation of downstream transcriptional programs.

As the mysteries stored in our DNA have been more completely revealed, scientists have begun to face the extraordinary challenge of unraveling the int- cate network of protein-protein interactions established by that DNA fra- work.

The generation of genetically modified mice is absolutely crucial to gene function studies today, primarily because mice are genetically similar to man and because gene function studies in mice are in the context of a whole organism, making them particularly useful.

In this updated third edition, expert physicians assemble user-friendly, clinically-oriented guides to aid in the day-to-day management of the allergic patient. This book is intended for the front-line physician who cares for allergic patients.

Inflammatory Dermatopathology: A Pathologist's Survival Guide provides expert guidance for the reader to develop a systematic approach to the diagnosis of inflammatory disorders of the skin.

The field of epigenetics has grown exponentially in the past decade, and a steady flow of exciting discoveries in this area has served to move it to the forefront of molecular biology.

Our intention, in In Situ Hybridization Protocols is to provide ample inf- mation for novices planning to set up the in situ hybridization technique and use it in their laboratory for the first time, as well as giving updates of recent developments for those laboratories where in situ hybridization techniques are already in use.

This complete laboratory reference manual explains the principles behind solid phase extraction (SPE) and provides readily reproducible protocols for solving extraction problems in forensic and clinical chemistry.

In Systems Biology in Drug Discovery and Development: Methods and Protocols, leading experts provide a practical, state-of-the-art, and holistic view of the translation of systems biology into better drug discovery and personalized medical practice.

Metagenomics has proven to be a powerful tool for exploring the ecology, metabolic profiling, and comparison of complex microbial communities as well as its important applications in the mining of metagenomes for genes encoding novel biocatalysts and drug molecules for bioindustries.

Cyberforensics is a fairly new word in the technology our industry, but one that n- ertheless has immediately recognizable meaning. As the word cyber has become synonymous with the use of electronic technology, the word cyberforensics bears no mystery.

Here, leading researchers describe the latest techniques for investigating the mechanisms underlying transcription factor nuclear-cytoplasmic trafficking, as well as the functional impact of post-translational modifications on transcription factor function.

A cutting-edge review of the latest findings on key scientific topics and the best strategies for evaluation and management of portal hypertension in the clinic.

This edition focuses not only on direct analysis of trinucleotide repeat diseases but also on alternative approaches for the analysis of trinucleotide repeat diseases, with the hope that this will result in a better understanding of the mechanisms and future therapeutic prospects for treatment of these diseases.

It is now well established that jasmonates, originally identified as the major component of jasmine scent, play a universal role in the plant kingdom and are involved in the regulation of diverse aspects of plant biology, including growth, development, metabolism, and interaction with the environment.

Importantly, major advances in our understanding of chemokine biology have led to chemokine receptors becoming specific therapeutic targets with great potential.

This Methods in Molecular Biology(TM) book offers protocols and updated methods with a particular focus on MS-based methods of protein and peptide quantification and the analysis of posttranslational modifications as well as descriptions of system biology methods.

This Methods in Molecular Biology(TM) book covers techniques for the discovery and development of microsatellite markers, descriptions of amplification and visualization of SSRs, and protocols for analyzing data obtained using microsatellites.

This Methods in Molecular Biology(TM) book covers mass spectrometry data analysis in quantitative proteomics, post translational modification, HX-MS, glycomics, and data exchange standards. Includes materials lists, reproducible protocols, tips and more.

This book details methods and protocols for the analysis of arteries, cells, lipoproteins, body fluids, and metabolites, with a particular focus on MS-based methods of protein and peptide quantification. Includes step-by-step, readily reproducible protocols.

This Methods in Molecular Biology(TM) book covers knowledge dissemination and theoretical assessment of OR structure and function, plus development and use of expression systems and experimental functional analysis. Offers reproducible protocols, tips and more.

These include methods and techniques for the analysis of necrosis in mammalian cells, characterization of alternative forms of cell death: entosis and pyroptosis, and analysis of cell death in non-mammalian model sytems and mammalian tissues, including chapters on skin, brain, and heart.

This Methods in Molecular Biology(TM) book covers chemical probes of membrane protein structure and function, photochemical control of protein and cellular function, and chemical probes for imaging the nervous system. Offers step-by-step protocols, tips and more.

This Methods in Molecular Biology(TM) book offers strategies and protocols for studying a large group of proteins that form ionic channels in the plasma membrane and intracellular membranes of cells. Includes step-by-step protocols, materials lists, tips and more.

Tissue engineering and regenerative medicine represents a wide array of cell, biomaterial and cell/biomaterial based approaches focusing on the repair, augmentation, and regeneration of diseases tissues and organs.

This book provides an unbiased comparison of the various photochemical tools currently available for controlling neuronal activity in order to aid scientists in the vital goal of choosing the right tools for the job.

Here is a collection of protocols for the analysis of viral small RNAs and natural antiviral RNAi responses as well as for development and optimization of RNAi-based antiviral drugs. The methods here can also be applied outside the context of a virus infection.