Bücher veröffentlicht von Humana Press Inc.

It details current technologies used in proteomics, examines the use proteomics in cell signaling, presents clinical applications of proteomics in cancer therapy, and looks at the role of the FDA in regulating the use of proteomics.

Knowledge of the role of redox in the control of cellular activity has recently expanded. In this book, experienced researchers contribute timely methods and techniques that can be used to study this important and expanding aspect of biology.

Here is a manual for an environmental scientist who wishes to embrace genomics to answer environmental questions. The volume covers: gene expression profiling, whole genome and chromosome mutation detection, and methods to assay genome diversity and polymorphisms within a particular environment.

Over the past two decades, expressed sequence tags (ESTs - single pass reads from randomly selected cDNAs), have proven to be a remarkably cost-effective route for the purposes of gene discovery.

As such, many techniques are required to understand the contribution and functions of neuropeptides in health and disease processes. Research in the neuropeptide field is aimed toward a better understanding of the physiology of the human body and toward the development of better diagnostics and therapeutics.

A highly anticipated update of the previous edition, In Vitro Transcription and Translation Protocols, Second Edition, provides molecular biology laboratories with the most powerful techniques for exploiting in vitro transcription and translation systems.

Protocols for Nucleic Acid Analysis by Non-radioactive Probes, Second Edition provides a firm background on the basic preparative protocols required for the analysis of nucleic acids by nonradioactive methods.

A multidisciplinary survey of our current understanding of the biological and clinical aspects of vascular disease. The complex relationship between VaD and AD is also fully explored with chapters on how these processes interact and how one disease may lower the threshold for clinical expression of the other.

A comprehensive collection of optimized methods for dissecting the mechanisms that control epidermal growth factors (EGF) and their regulators in both normal and pathological states.

This new edition covers the latest knowledge on opiate receptors and related receptor subtypes. It discusses many topics pertaining to the unique integrated approach of correlating the biochemical, physiological and pharmacological aspects of opiate reaction.

Small molecule microarrays (SMM) were introduced just a decade ago in 1999 and, within a short space of time, have already established themselves as a vibrant, next generation platform for high-throughput screening.

Chapters outline methods to study miRNA functions in various cell types from a single cell type level to entire model organisms, and present studies of miRNAs in the context of viruses and the immune response.

Membrane proteins, representing nearly 40 per cent of all proteins, are key components of cells involved in many cellular processes, yet only a small number of their structures have been determined. This title offers many detailed techniques for membrane protein structure determination by bringing together contributions from experts in the field.

This comprehensive contemporary survey of the non-motor facets of Parkinson's disease has now been fully updated and expanded for a new edition that covers all the autonomic, sensorimotor, sleep-related, and sensory aspects of non-motor dysfunction.

Research has revealed that natural killer (NK) cells are sentinels of the innate immune response. This text offers detailed protocols plus the latest methods and techniques designed to study NK cells within specialized tissue sites in both mice and humans.

As two of the leading causes of death worldwide, heart disease and stroke represent a clear target for genomic research aimed at deciphering the genes and cellular pathways that underlie cardiovascular disease and creating improved therapies.

This comprehensive, yet practical, text is a ready collection of the most up-to-date information on primary CNS tumors. The opening chapters cover general principles, including epidemiology, pathogenesis, tumor stem cells, supportive care, complications of therapy, and quality of life.

Ranging from the evolution of pathogenicity to oceanic carbon cycling, the many and varied roles that bacteriophages play in microbial ecology and evolution have inspired increased interest within the scientific community.

Brain Hypoxia and Ischemia explores the various aspects of cell death and survival that are crucial for understanding the basic mechanisms underlying brain hypoxia and ischemia.

Population studies and epidemiology facilitate the discovery of genetic and environmental determinants of cancer and the development of new approaches to cancer control and prevention, therefore they play a central role in the creation of health policies.

Exciting new biological functions are still being discovered for vitamin A derivatives, including the myriad physiological activities of retinoids. Here, experts in the field present the latest range of techniques for both in-vitro and in-vivo studies.

Until now, there are several good books on telomere and telomerase focusing on biology in ciliates, yeasts, and mouse or basic sciences in human, providing basic scientists or students with updated knowledge.

In this second edition, the world's leading experts on prostate cancer detection update the previous edition with the latest findings. It incorporates a series of thoughtful and cutting-edge works from the world's experts in prostate cancer screening.

Advanced Protocols in Oxidative Stress I covers the field of oxidative stress with state-of-the-art technology to utilize in research, contributed by an international panel of experts renowned for developing new procedures and methods.

This book reveals not only how the eye evolved into an organ of vision, but also describes how molecular mechanisms of key molecules operate in the phototransduction cascade.

In the areas of biochemistry and cell biology, characterizations of stability and molecular interactions call for a quantitative approach with a level of precision that matches the fine tuning of these interactions in a living cell.

In this authoritative book, experts in the field present a collection of detailed techniques for studying G-quartet formation, dynamics, and molecular recognition. It provides detailed protocols which ensure successful re-recreation of experimental procedures.

The radical expansion and revision of techniques and experimental approaches employed in the study of adipose tissue are reflected in this revised book.

This book serves as an easy entry point for those investigating the factors responsible for the pathogenicity of microorganisms. The step-by-step laboratory protocols study host-pathogen interaction, with a focus on fungal, bacterial and parasitic pathogens.

In this volume, top researchers provide hands-on protocols describing the process of non-viral delivery of genetic materials such as DNA in order to better treat disease.