Bücher veröffentlicht von Humana Press Inc.

As membrane trafficking research has expanded over the past thirty years, a remarkable convergence of information has been gained by using genetic approaches in yeast cells with biochemical approaches in mammalian cells.

In the last 20 years, research activity using the zebrafish Danio rerio has increased dramatically. In this book, experts provide a collection of experimental techniques for the genetic modification, manipulation, and in vivo live imaging of zebrafish.

Stroke Essentials for Primary Care: A Practical Guide is a must-have resource, offering the essential, practical knowledge required to evaluate and treat stroke patients.

This volume details the latest technology in treating eye injuries and infections. Coverage reviews issues such as intraocular lens implants, biocompatibility of materials, retinal implants, testing models, and software designs.

Nucleic acid aptamers and peptide aptamers are two vital molecule types often employed for in vitro selection procedures. This book presents state-of-the-art methodologies for the isolation, characterization, and application of these two molecule types.

The aim of Molecular Mechanisms of Neurotransmitter Release is to provide up-to-date, in-depth coverage of essentially all major mole- lar mechanisms of neurotransmitter release.

A valuable resource for researchers, developers, and clinicians, the book presents a foundation to propel the technology and integration of the current state of knowledge into the 21st century.

If a picture is worth a thousand words, then dynamic images of brain activity certainly warrant many, many more. the ?rst one contains a brief pre- ble to dynamic brain imaging and the other presents a novel, analytical approach to processing of dynamically acquired data.

In a single volume this book assembles the various tools and methodologies needed by the interested investigator to unravel lipid dependent signaling and cell function. This is an essential resource for both experienced and novice researchers.

Stroke is the leading cause of serious, long term disability. This book proposes different cellular therapies under investigation to promote neural regeneration after stroke. Authored by an international panel of scientists and clinicians, this volume is a vital, one-of-a-kind resource for all scientists interested in regenerative medicine.

Focusing on the molecular characteristics, localization, and substrate specificities in various compartments of the eye, this volume discusses how transporters regulate the clarity of the cornea and lens, the movements of fluids across the ciliary epithelium and nutrients across the retinal pigment epithelium.

Over 2000 years ago in China, antibodies elicited by early forms of vaccination likely played a major role in the protection of the population from infectious agents. This explosion of research and development in the field of therapeutic antibodies prompted the publication of the MiMB volume Therapeutic Antibodies: Methods and Protocols.

Today, with the advent of new technologies, this ?eld has grown to include not only diseases that affect the skeleton but also those that affect muscles, ligaments, tendons, and also the cartilaginous structures within joints.

Written by a prestigious group of international contributors, individual chapters in Adrenal Imaging serve as a relevant and up-to-date reference of adrenal imaging findings, algorithms and techniques in CT, MR nuclear medicine, intervention and trauma.

Reporter genes have played, and continue to play, a vital role in many areas of biological research by providing a ready means for qualitative and quantitative assessment of the activity of genes and location of gene products in different environments.

In particular, the methods can be used to identify in clinical samples those genetic mutations responsible for such congenital abnormalities as Marfan syndrome, Williams-Beuren Syndrome, Alagille syndrome, Noonan syndrome, and Friedreich ataxia.

In this second edition, the world's leading experts on prostate cancer detection update the previous edition with the latest findings. It incorporates a series of thoughtful and cutting-edge works from the world's experts in prostate cancer screening.

Made possible by the advent of modern methodology, and ideal for both experienced and novice scientists, this volume provides an up-to-date collection of approaches that can be used to investigate how the mechanism of mitosis operates at the molecular level.

Hormesis is a poorly understood phenomenon affecting all forms of life on earth. This groundbreaking book summarizes and analyzes the various positives of hormesis in an attempt to reveal hormesis as a fundamental principle of biomedical sciences as a whole.

In light of the critical contributions of macrophages and dendritic cells to diverse inflammatory diseases and to immunity and host defense, state-of-the-art approaches to the investigation of their behavior are essential.

The study of bone cells and tissues at the cellular and molecular levels in a variety of models has revolutionized the field. In this book, leading scientists from around the world share their step-by-step laboratory protocols for studying bone biology.

Over the last 20 years, pediatric otolaryngology has become a recognized subspecialty within otolaryngology head and neck surgery.

This volume contains a series of reviews that are c- cerned with how epithelial plasma membranes regulate the transport of solutes between the intracellular and extracellular compartments of a cell.

This book presents a comprehensive review of the inflammatory myopathies, including dermatomyositis, polymyositis, and inclusion body myositis. Representing the most up-to-date knowledge on this family of diseases, this book is the gold-standard in its field.

This fully updated and expanded edition details the transgenic techniques currently used to modify the genome. It explores classic procedures as well as cutting-edge practices involving microinjection, site-specific recombination systems, and cryopreservation.

In medical practice there are often complex cases that make extraordinary demands on a clinician's knowledge and ingenuity. In Challenging Cases in Allergy and Immunology, the authors provide these types of fascinating, and informative cases to complement a basic knowledge of diagnosis and management in these fields.

Despite its inherent controversy, the exploration of the human embryo can unlock many answers to deep biological questions. In this book, internationally recognized researchers contribute detailed methods to analyze aspects of the embryogenesis process.

Following the completion of the mouse and human genome sequences, a major challengeisthefunctionalcharacterizationofeverymammaliangeneandthedeciph- ing of their molecular interaction network.

In this book, experts in proteomic research contribute detailed techniques which present an overview of the contemporary challenges and possibilities in the various areas of proteomics. The book makes a valuable contribution to proteomics research.

Despite recent advances in the diagnosis and treatment of symptomatic atherosclerosis, available traditional screening methods for early detection and treatment of asymptomatic coronary artery disease are grossly insufficient and fail to identify the majority of victims prior to the onset of a life-threatening event.