Bücher veröffentlicht von IntechOpen

The aim of this book is to present the terminology, applications, trends, and developments in Product Lifecycle Management (PLM). This book has a total of seven chapters that treat the fundamental and future terminology used in PLM, aspects regarding the design, customization, and development of products, products testing, supply chain optimization, and recycling of the products made of special materials.

Immunization plays a key role in maintaining human health and each year, saves millions of lives from lethal pathogens and other fatal diseases in the most economical way, thanks to the advanced development of model vaccines. Subunit vaccines are regarded as a safer product than the whole microbe based-conventional vaccines and can be entrapped in various nanocarriers to form a vaccine adjuvant-delivery system (VADS) able to further boost their immunostimulatory activity. In this book, six groups of authors introduce immunization advances in VADSs designed for infection prophylaxis and cancer immunotherapy, problems and their resolution in both human and poultry immunization, and also, the mathematical model for assay of the basic immunization problem (BIP) understood from a finance point of view.

This book describes recent findings on androgens. The chapters include information on physiological and pathological conditions such as alteration in testosterone production by Leydig cells, prostate cancer, and metabolic disorders. Moreover, this book refers to the potential use of androgens in assisted human reproduction treatments and bovine breeding. Since each chapter contains background information based on evidence and emphasizes basic science, this book is aimed at professionals who already have a basic understanding of the principles of androgen biochemistry and endocrine-related diseases.

Melatonin, the pineal neurohormone, is a pleiotropic molecule acting in the center of the integrative molecular mechanisms of the organism, based on interconnections of the regulatory systems: neural, endocrine, immune, and genetic, conveying into the uniqueness of human architecture. This book provides a systematic and updated overview of melatonin biochemical mechanisms of action, pharmacological features, and clinical uses, clutching the subject with complete details of pharmaceutical formulations designed for different routes of administration and different health issues, aiming at optimal melatonin bioavailability when therapeutically delivered. The book addresses a broad range of audiences, from healthcare professionals, medically and pharmaceutically based, to highly profiled medical specialists and biomedical researchers, helping them to expand their knowledge of the physiological and pathological implications of melatonin and its metabolites.

The development and implementation of new technology devices to help professionals, athletes, and non-athletes improve their physical fitness, performance, health, and well-being have emerged in the last few years. This book briefly overviews the current state of the art in technology applied to sports, providing examples, literature syntheses, and recent applications to sports, focused on the most important evidenced-based developments in this area. Attention is drawn to issues and unusual matters that may arise when it comes to technological innovation applied to sport. For the reader, this could be a different perspective on technological progress in physical activity.

This book is a collection of five original research articles on silicon photonics. The discussed issues are organized into two parts. Part 1 describes the science behind the silicon photonics emphasizing the role of photonic circuits on silicon, and Part 2 describes applications in waveguide and optical transmissions. This book should be of interest to academic researchers and engineers. The chapters included are fundamental science and applications of silicon photonics, optical properties of thin nanocrystalline silicon films, microporous silicon in gas sensing, Mach-Zehnder interferometer cell-based silicon waveguide, experimental study of porous silicon films, and integrated optical switches and their applications.

Consumer product acceptance and market success are dependent on the product's aroma/flavour. Flavours can be produced through chemical synthesis, microbial biocatalysis or by extraction from plants and animal sources. In recent times, chemical synthesis is not as desirable as this is not eco-friendly. So, in the food industry, natural ingredients are added to preparations for efficiency, softness or emotional appeal. Microbiology, bioengineering and biochemistry have enabled the elucidation of metabolic pathways; genetic engineering is expected to help in identifying metabolic blockages and creating novel high-yielding strains, while proteomics help in the application of analytical techniques. All these sciences, old and new, will lead to innovative ideas in the quest for better, sustainable and consumer-approved flavours and aromas.

This book offers remarkable coverage of liver cancer from etiology to prevention and treatment. It provides an updated and new vision of this major cancer that continues to affect hundreds of thousands of people and remains one of the leading causes of cancer deaths around the world. To ensure the high quality of this book, important insights are included and rigorously discussed in a simple and authentic way. The book includes detailed and updated descriptions of the main causes of liver cancer and also the prevention and treatment of this disease. This book is a relevant source of knowledge, very useful for researchers, medical doctors, medical residents, students, healthcare providers, public health decision makers, and all individuals interested in the prevention of this disease.

The human hypothalamus, a small structure at the base of the brain, has strategic importance for the harmonic function of the human body. It controls the autonomic nervous system, neuroendocrine function, circadian and circannual rhythms, somatic activities, and behavior, and is situated at the borders between the brain and the body and the brain and the soul, meeting points for mind and body. The hypothalamus is involved in a wide range of higher mental functions, including attention, learning and reinforcement of mnemonic processes, emotional control, mood stability, and cognitive-emotional interactions. It also has a role to play in behavioral disorders, panic reactions, cluster headache, gelastic epilepsy, mental deficiency, periodic disorders, depression, autism, and schizophrenia, and in a substantial number of neurodegenerative diseases. It enlarges greatly the dimensions of the hypothalamic contribution in controlling psychosomatic equilibrium and retaining internal unity of the human existence.

Plasmonics gives researchers in universities and industries and designers an overview of phenomena enabled by artificially designed metamaterials and their application for plasmonic devices. The purpose of this book is to provide a detailed introduction to the basic modeling approaches and an overview of enabled innovative phenomena. The main research agenda of this book is aimed at the study of modeling techniques and novel functionalities such as plasmonic enhancement of solar cell efficiency, plasmonics in sensing, etc. The topics addressed in this book cover the major strands: theory, modeling and design, applications in practical devices, fabrication, characterization, and measurement. It is worthwhile mentioning that the strategic objectives of developing new artificial functional materials require close cooperation of the research in each subarea.