Bücher veröffentlicht von IntechOpen

Prostate cancer is diagnosed commonly in the course of general health screening. Very often it is difficult to tell whether the cancer will be aggressive and lethal or will be so slow growing that it will not affect the patient's survival. Treatment can have a major impact on the patient's health-related quality of life. This book presents cutting-edge research in predicting the behavior of localized and metastatic cancer, targeted treatment of cancer that has spread minimally, response to newer methods of treatment, and rehabilitation of patients.

The dementia challenge is the largest health effort of the times we live in. The whole society has to move to a realization of the significance of prioritization to make an attempt in the direction of mental health promotion and dementia risk reduction. New priorities for research are needed to go far beyond the usual goal of constructing a disease course-modifying medication. Moreover, a full empowerment and engagement of men and women living with dementia and their caregivers, overcoming stigma and discrimination should be promoted. The common efforts and the final aim will have to be the progress of a ''dementia-constructive'' world, where people with dementia can take advantage of equal opportunities.

The book presents interesting topics from the area of modeling and simulation of electric vehicles application. The results presented by the authors of the book chapters are very interesting and inspiring. The book will familiarize the readers with the solutions and enable the readers to enlarge them by their own research. It will be useful for students of Electrical Engineering; it helps them solve practical problems.

Carbon atoms have the amazing ability to bond in remarkable different manners that can assume distinct astonishing dimensional arrangements from which absolutely diverse and interesting nanostructured carbon materials are obtained. This book aims to cover the most recent advances in (i) Graphene and derivatives, including graphene-based magnetic composites, membranes, wafer devices, and nanofibers for several applications, as well as some particular properties, such as light emission from graphene; (ii) Carbon nanotubes heaters and fibers for reinforcement of cement and diamond-based thin films; and (iii) Nanofluids consisting of both graphene and carbon nanotubes, apart from reporting some important case studies dealing with carbon nanostructures and their use in sensors, coatings, or electromagnetic wave absorbers.

Metastasis is the major cause of cancer-related death. It is a multistep process. The mechanism underlying metastasis is complicated and poorly understood. Recent advances in tumor metastasis research have led to improved diagnosis and clinical management of cancer. However, new strategies on metastasis treatment are urgently needed, especially the novel biomarkers discovery and targeted therapy. This book is designed to present the most recent advances in tumor metastasis.

This book gives information and guidance on important subjects. It presents the major and efficient applications for efficient insulation materials. The book is divided into two parts.Part I discusses ecological insulation materials. In this part, the three sub-subjects are drafting, Unconventional insulation materials, Jute-Based Insulation Material, and Possible Applications of Corn Cob as a Raw Insulation Material.Part II: discusses Practical Applying and Performance of Insulation Materials (case studies), where three sub-subjects are drafting seismic aspects of the application of thermal insulation boards beneath the building's foundations, flammability of bio-based rigid polyurethane foam thermal insulation, and the review of some commonly used methods and techniques to measure the thermal conductivity of insulation materials.

This book is an update on environmentally sound pest management practices under the umbrella of integrated pest management (IPM). It consists of seven contributions from different authors providing information on pest management approaches as chemical alternatives. The book chapters detail about historical review of IPM concepts; strategies and some experiences in applications of IPM in Latin America; pest control in organic agricultural system; and the use of entomopathogenic and molluscoparasitic nematodes, insect pheromones, semiochemicals, detergents, and soaps as a part of IPM scheme. The goal of this book is to provide the most up-to-date review on information available around chemical alternatives in IPM. Therefore, this book will equip academia and industry with adequate basic concepts and applications of IPM as eco-friendly pest management option.

Essential hypertension is a quantitative characteristic that is important for correlating with the rate of morbidity and mortality in the developed and developing countries. The etiology of essential hypertension is complex. This work, authored by renowned researchers in the field, gives updated concepts about essential hypertension. Novel advanced topics are presented in a sole document as hypertension in children; the contribution in the psychiatric comorbidities associated with it; mechanisms of omega-3 in protection against hypertension-related organ damage; oxidative stress at different levels; genetics-associated studies; the role of pollution in essential hypertension; personalized healthcare in a hypertensive patient; and hypertension-related disparities between ethnic groups. It can conclude so that essential hypertension is one of the hottest topics in contemporary medicine.

This book features state-of-the-art contributions in mathematical, experimental and numerical simulations in engineering sciences. The contributions in this book, which comprise twelve chapters, are organized in six sections spanning mechanical, aerospace, electrical, electronic, computer, materials, geotechnical and chemical engineering. Topics include metal micro-forming, compressible reactive flows, radio frequency circuits, barrier infrared detectors, fiber Bragg and long-period fiber gratings, semiconductor modelling, many-core architecture computers, laser processing of materials, alloy phase decomposition, nanofluids, geo-materials and rheo-kinetics. Contributors are from Europe, China, Mexico, Malaysia and Iran. The chapters feature many sophisticated approaches including Monte Carlo simulation, FLUENT and ABAQUS computational modelling, discrete element modelling and partitioned frequency-time methods. The book will be of interest to researchers and also consultants engaged in many areas of engineering simulation.

This book covers state-of-the-art optimization methods and their applications in wide range especially for researchers and practitioners who wish to improve their knowledge in this field. It consists of 13 chapters divided into two parts: (I) Engineering applications, which presents some new applications of different methods, and (II) Applications in various areas, where recent contributions of state-of-the-art optimization methods to diverse fields are presented.

This book covers some special issues relevant to peritoneal dialysis and is a guide to the clinical practice of peritoneal dialysis. A team of international experts presents the latest information about novel peritoneal solutions, pharmacological preservation of peritoneal membrane, peritoneal dialysis catheters, assessment of volume status in PD patients, management of exit-site infection, microbiology of PD peritonitis, peritoneal dialysis in acute renal failure, and peritoneal dialysis and pregnancy.

This book gives the readers an introduction to experimental and theoretical knowledge acquired by large-scale laser laboratories that are dealing with extra-high peak power and ultrashort laser pulses for research of terawatt (TW), petawatt (PW), or near-future exawatt (EW) laser interactions, for soft X-ray sources, for acceleration of particles, or for generation of hot dense thermal plasma for the laser fusion. The other part of this book is dealing with the small-scale laser laboratories that are using for its research on commercial sources of laser radiation, nanosecond (ns), picosecond (ps), or femtosecond (fs) laser pulses, either for basic research or for more advanced applications.This book is divided into six main sections dealing with short and ultrashort laser pulses, laser-produced soft X-ray sources, large-scale high-power laser systems, free-electron lasers, fiber-based sources of short optical pulse, and applications of short pulse lasers. In each chapter readers can find fascinating topics related to the high energy and/or short pulse laser technique.Individual chapters should serve the broad spectrum of readers of different expertise, layman, undergraduate and postgraduate students, scientists, and engineers, who may in this book find easily explained fundamentals as well as advanced principles of particular subjects related to these phenomena.

Advanced oral and maxillofacial surgery encompasses a vast array of diseases, disorders, defects, and deformities as well as injuries of the mouth, head, face, and jaws. It relates not only to treatment of impacted teeth, facial pain, misaligned jaws, facial trauma, oral cancers, jaw cysts, and tumors but also to facial cosmetic surgery and placement of dental and facial implants. This specialty is evolving alongside advancements in technology and instrumentation. Volume 1 has topped 132,000 chapter downloads so far, and Volume 2 is being downloaded at the same pace! Volume 3 is basically the sequel to Volumes 1 and 2; 93 specialists from nine countries contributed to 32 chapters providing comprehensive coverage of advanced topics in OMF surgery.

This book brings together some recent advances and development in robotics. In 12 chapters, written by experts and researchers in respective fields, the book presents some up-to-date research ideas and findings in a wide range of robotics, including the design, modeling, control, learning, interaction, and navigation of robots. From an application perspective, the book covers UAVs, USVs, mobile robots, humanoid robots, graspers, and underwater robots. The unique text offers practical guidance to graduate students and researchers in research and applications in the field of robotics.

In this book, you'll learn multiple new aspects of respiratory management of the newborn. For example, ventilator management of infants with unusually severe bronchopulmonary dysplasia and infants with omphalocele is discussed, as well as positioning of endotracheal tube in extremely low birth weight infants, noninvasive respiratory support, utilization of a protocol-driven respiratory management, and more. This book includes a chapter on noninvasive respiratory function monitoring during chest compression, analyzing the efficacy and quality of chest compression and exhaled carbon dioxide. It also provides an overview on new trends in the management of fetal and transitioning lungs in infants delivered prematurely. Lastly, the book includes a chapter on neonatal encephalopathy treated with hypothermia along with mechanical ventilation. The interaction of cooling with respiration and the strategies to optimize oxygenation and ventilation in asphyxiated newborns are discussed.

Hemodiafiltration (HDF) is an advanced renal replacement therapy that can reduce morbidity and mortality and improve the quality of life of dialysis patients. This special edition of the Advances in Hemodiafiltration book is empowered with several well-established and experienced authors, who have written clear and informative chapters. The book covers basic physiologic principles of HDF and its requirements, implementation, and achievement of best possible clinical outcomes and includes results of published randomized controlled clinical trials. Advances in Hemodiafiltration can be considered as a practical guide to daily practice and a reference for medical and nursing staff involved in taking care of dialysis patients.

Numerous studies had been performed to elucidate the mechanisms of aging and to achieve rejuvenation, with some success reported in recent years. However, at present, the findings from those studies are not sufficient to resolve the issue of aging. This book presents an overview of recent topics on cellular aging and rejuvenation. In the early chapters, the molecular mechanisms of aging via the activities of clock and ion channel proteins, in addition to overall aspects, are discussed. In the latter part, the aging of the skin, immune system, and brain is discussed. This book will prove useful for those studying or developing new drugs to counter the aging process and will encourage the development of novel ideas for rejuvenation.

The book ''Applied Studies of Coastal and Marine Environments'' is a collection of a number of high-quality and comprehensive work on coastal and marine environment. This book has an Introductory Chapter, followed by 15 chapters. Chapters 2 and 3 are devoted to coastal geological sedimentation and its impacts on marine environment. Consequently, Chapter 4 investigates neo-tectonic movement in the Pearl River Delta. Different aspects of the coastal pollution and its impacts are addressed in Chapter 5 through Chapter 13. Furthermore, coastal management is also discussed in Chapter 14, and monitoring the coastal environment using remote sensing and GIS techniques is reported in Chapter 15. Finally, Chapter 16 addresses the human history of maritime exploitation and adaptation process to coastal and marine environments. It is important to investigate the history of maritime exploitation and adaptation to environment coastal zone to learn how to explore the oceans.

Advanced Techniques in Bone Regeneration is a book that brings together over 15 chapters, written by leading practitioners and researchers, of the latest advances in the area, including surgical techniques, new discoveries, and promising methods involving biomaterials and tissue engineering.This book is intended for all who work in the treatment of disorders involving problems with the regeneration of bone tissue, are doctors or dentists, as well as are researchers and teachers involved in this exciting field of scientific knowledge.

During the dyeing process, losses of colorants to the water sources can be toxic and mutagenic and also decreases light penetration and photosynthesis activity. In recent years, since textile industry can generate large volumes of effluents, textile wastewater treatments have received considerable attention. The aim of this book is to look into textile wastewater treatments shortly. It is designed for readers who study on textile dyeing effluent. I would like to record my sincere thanks to authors for their contributions.

Metallic glasses and amorphous materials have attracted much more attention in the last two decades. A noncrystalline solid produced by continuous cooling from the liquid state is known as a glass. From the other point of view, a noncrystalline material, obtained by any other process, for example, vapor deposition or solid-state processing methods such as mechanical alloying, but not directly from the liquid state, is referred to as an amorphous material. At this moment, bulk metallic glasses (BMG) are appearing as a new class of metallic materials with unique physical and mechanical properties for structural and functional usage. Extreme values of strength, fracture toughness, magnetic properties, corrosion resistance, and other properties have been registered in BMG materials.

The book Ebola is a relevant resource of knowledge about various aspects of the Ebola virus (EBOV) and the related disease. Many experts from different fields of science and from different parts of the world contributed to the creation of this book. The book contains valuable information about firsthand experience of managing Ebola virus disease (EVD) in Third World countries and offers the best practices to handle possible pandemic outbreaks of Ebola. Detailed analysis of EBOV genome is also given, with the description of EBOV pathology supported with structural information, and in addition, the various tasks and strategies for the development of an effective anti-Ebola cure are proposed.

Scope of Selective Heterocycles from Organic and Pharmaceutical Perspective is a compilation of bioactive-chosen heterocyclic scaffolds intended for postgraduates, research scholars, pharmaceutical scientists, and others interested in an appreciation of the title subject. It is an edited book and is not comprehensive as well in the mentioned field. Few synthetic strategies along with bioactivity are presented, and some limitations were raised in order to arouse curiosity of the reader.

The use of biomarkers in basic and clinical research has become routine in many areas of medicine. They are accepted as molecular signatures that have been well characterized and repeatedly shown to be capable of predicting relevant disease states or clinical outcomes. In Role of Biomarkers in Medicine, expert researchers in their individual field have reviewed many biomarkers or potential biomarkers in various types of diseases. The topics address numerous aspects of medicine, demonstrating the current conceptual status of biomarkers as clinical tools and as surrogate endpoints in clinical research. This book highlights the current state of biomarkers and will aid scientists and clinicians to develop better and more specific biomarkers for disease management.

There continue at present many developments in the area of quantum mechanics and quantum dynamics in particular, of a very fundamental nature, all the way from implications for the foundations of physics to the influence of quantum mechanics on emerging technologies, such as the areas of quantum semiconductors and quantum computing, both of which are very important examples. It is hoped that the papers in this volume will be able to provide a much needed resource for researchers with regard to current fields of research in this dynamic area.

E-waste management is a serious challenge across developed, transition, and developing countries because of the consumer society and the globalization process. E-waste is a fast-growing waste stream which needs more attention of international organizations, governments, and local authorities in order to improve the current waste management practices. The book reveals the pollution side of this waste stream with critical implications on the environment and public health, and also it points out the resource side which must be further developed under the circular economy framework with respect to safety regulations. In this context, complicated patterns at the global scale emerge under legal and illegal e-waste trades. The linkages between developed and developing countries and key issues of e-waste management sector are further examined in the book.

Probiotic microorganisms are recognised as being beneficial for human health. Prebiotics are substrates that are used preferentially by the probiotic bacteria for their growth. A great deal of interest has been generated in recent years in identifying probiotic bacteria and prebiotics, their characterization, mechanisms of action and their role in the prevention and management of human health disorders. Together they are referred to as synbiotic. This book is in response to the need for more current and global scope of probiotics and prebiotics. It contains chapters written by internationally recognized authors. The book has been planned to meet the needs of the researchers, health professionals, government regulatory agencies and industries. This book will serve as a standard reference book in this important and fast-growing area of probiotics and prebiotics in human nutrition and health.

Photocatalysis is a hot topic because it is an environmentally friendly approach toward the conversion of light energy into chemical energy at mild reaction environments. Also, it is well applied in several major areas such as water splitting, bacterial inactivation, and pollutants elimination, which is a possible solution to energy shortage and environmental issues. The fundamental knowledge and the frontier research progress in typical photocatalytic materials, such as TiO2-based and non-TiO2-based photocatalysts, are included in this book. Methods to improve the photocatalytic efficiency and to provide a hint for the rational design of the new photocatalysts are covered.

Pluripotent stem cells have distinct characteristics: self-renewal and the potential to differentiate into various somatic cells. In recent years, substantial advances have been made from basic science to clinical applications. The vast amount knowledge available makes obtaining concise yet sufficient information difficult, hence the purpose of this book. In this book, embryonic stem cells, induced pluripotent stem cells, and mesenchymal stem cells are discussed. The book is divided into five sections: pluripotency, culture methods, toxicology, disease models, and regenerative medicine. The topics covered range from new concepts to current technologies. Readers are expected to gain useful information from expert contributors.

The book contains 10 chapters, and it is divided into four sections. The first section includes three chapters, providing an overview of Energy Management of Distributed Systems. It outlines typical concepts, such as Demand-Side Management, Demand Response, Distributed, and Hierarchical Control for Smart Micro-Grids. The second section contains three chapters and presents different control algorithms, software architectures, and simulation tools dedicated to Energy Management Systems. In the third section, the importance and the role of energy storage technology in a Distribution System, describing and comparing different types of energy storage systems, is shown. The fourth section shows how to identify and address potential threats for a Home Energy Management System. Finally, the fifth section discusses about Economical Optimization of Operational Cost for Micro-Grids, pointing out the effect of renewable energy sources, active loads, and energy storage systems on economic operation.