Bücher veröffentlicht von Springer Berlin Heidelberg

Avalanches, debris, mudflows and landslides are common and natural phenomena that occur worldwide, predominantly in mountainous regions. With an emphasis on snow avalanches, this book sets out to provide a survey and discussion about the motion of avalanche-like flows from initiation to run out. An important aspect of this book is the formulation and investigation of a simple but appropriate continuum mechanical model for the realistic prediction of geophysical flows of granular material. This will help the practitioners in the field to better understand the physical input and provide them with a tool for their work. Originating from many lectures the authors have given over the years, this instructive volume brings the reader to the forefront of research - an aim also supported by an extensive bibliogrpahy of almost 500 entries. Avalanche Dynamics should be accessible to, and is intended for, a broad readership of researchers, graduate students and practitioners with backgrounds in geophysics, geology, civil and mechanical engineering, applied mathematics and continuum physics.

Mammalian and Avian Transgenesis presents a collection of novel methods for the production of a wide range of transgenic animals. The manual focuses largely on mice, but also contains protocols for successful transgenesis in rats, cows, pigs and birds. The manual provides detailed, step-by-step protocols covering all aspects of the production of transgenic animals, including the use of lentiviral vectors in gene transfer, intracytoplasmic sperm injection, nuclear transfer, large insert transgenesis, conditional gene expression systems, the use of reporter genes in transgenesis and transgenesis in large animals and birds. The text is supplemented by superb color photos. While the focus is on newly established techniques, the fundamental methods of transgenesis are also covered for those new to the field. Thus this manual is perfectly suited for those wishing to adopt new technologies in transgenesis.

This book presents theoretical as well as experimental articles focused on recent new results in high temperature superconductivity. All contributors are high ranking scientists who have done major work to enhance the understanding of this phenomenon. A few articles deal with ferroelectricity and its applications. The book is dedicated to Prof. Dr. K. Alex Muller on his 80th birthday. During his scientific career he made major advances in the understanding of ferroelectricity.

We are now on the verge of viewing effector molecules and other regulatory sites as therapeutic targets for the amelioration of human and animal disease. The recognition, for example, that mutant proteins are frequently misrouted molecules, rather than functionally defective ones, changes our approach to "e;inborn errors of metabolism"e; and offers new approaches for pharmacological discovery, based on rescue of receptors, ion channels and enzymes with pharmacoperones. Ion channels, regulators of G-protein signaling and enzymes engaged in regulation, now present opportunities for drug development.The state of our art also benefits by the availability of superior tools that allow measurement of interactions and afford unprecedented insight into the biomolecular interactions that present novel approaches to drug design.

Few fields have witnessed such impressive advances as image processing in radiology. The progress achieved has revolutionized diagnosis and greatly facilitated treatment selection and accurate planning of procedures. This book, written by leading experts from many countries, provides a comprehensive and up-to-date description of how to use 2D and 3D processing tools in clinical radiology. The first section covers a wide range of technical aspects in an informative way. This is followed by the main section, in which the principal clinical applications are described and discussed in depth. To complete the picture, a third section focuses on various special topics. The book will be invaluable to radiologists of any subspecialty who work with CT and MRI and would like to exploit the advantages of image processing techniques. It also addresses the needs of radiographers who cooperate with clinical radiologists and should improve their ability to generate the appropriate 2D and 3D processing.

For every galaxy in the field or in clusters, there are about three galaxies in groups. The Milky Way itself resides in a group, and groups can be found at high redshift. The current generation of 10-m class telescopes and space facilities allows the observation of the members of nearby groups with exquisite detail, and their properties can be correlated with the global properties of their host group. Groups in the local Universe offer us the chance to study galaxies in environments characterized by strong interactions. In the cosmological context, groups trace large-scale structures better than clusters, and the evolution of groups and clusters appears to be related. All these aspects of research on groups of galaxies are summarized in this book written by scientists working in various fields.

Chemical peeling is a well known method attempting to restore a more youthful appearance and improving dermatologic defects. Over the last years this technique has been marked by constant innovation. This book is the first atlas on chemical peels, representing the state of the art in this field. It is a fully illustrated text, becoming an ideal reference tool for dermatologists dealing with cosmetology. It is a practical and simple guide: in the first part the peeling techniques are displayed in a step-by-step manner with an exhaustive text supporting the illustrations; in the second part different diseases are discussed in their pathogenesis and treatment options. Each Author then provides his/her personal experience and treatment approach with different peeling techniques in acne, rosacea, melasma, photoaging, postinflammatory hyperpigmentations and dark skin.

The text of this book has its origins more than twenty- ve years ago. In the seminar of the Dutch Singularity Theory project in 1982 and 1983, the second-named author gave a series of lectures on Mixed Hodge Structures and Singularities, accompanied by a set of hand-written notes. The publication of these notes was prevented by a revolution in the subject due to Morihiko Saito: the introduction of the theory of Mixed Hodge Modules around 1985. Understanding this theory was at the same time of great importance and very hard, due to the fact that it uni es many di erent theories which are quite complicated themselves: algebraic D-modules and perverse sheaves. The present book intends to provide a comprehensive text about Mixed Hodge Theory with a view towards Mixed Hodge Modules. The approach to Hodge theory for singular spaces is due to Navarro and his collaborators, whose results provide stronger vanishing results than Deligne¿s original theory. Navarro and Guill en also lled a gap in the proof that the weight ltration on the nearby cohomology is the right one. In that sense the present book corrects and completes the second-named author¿s thesis.

Nowadays neural computation has become an interdisciplinary field in its own right; researches have been conducted ranging from diverse disciplines, e.g. computational neuroscience and cognitive science, mathematics, physics, computer science, and other engineering disciplines. From different perspectives, neural computation provides an alternative methodology to understand brain functions and cognitive process and to solve challenging real-world problems effectively. Trends in Neural Computation includes twenty chapters either contributed from leading experts or formed by extending well selected papers presented in the 2005 International Conference on Natural Computation. The edited book aims to reflect the latest progresses made in different areas of neural computation, including theoretical neural computation, biologically plausible neural modeling, computational cognitive science, artificial neural networks - architectures and learning algorithms and their applications in real-world problems.

"e;Relativistic Astrophysics and Cosmology"e; have developed into important and fruitful research areas with a hitherto unprecented public interest. The year 2005, which marked the 100th anniversary of the 'annus mirabilis', that year in which Albert Einstein published three of his most important scientific papers, was the perfect opportunity to review and to present the current scientific understanding of relativistic topics including cosmological models, cosmology related measurements, the large scale properties of the Universe, dark matter and dark energy, the theory of gravity, black holes, theory and measurements, active galactic nuclei, clusters of galaxies, jets. Each of these subjects is addressed and the book represents a useful reference tool both for the expert and the new-comer in these fields.