Bücher veröffentlicht von Springer International Publishing

This book provides a comprehensive overview of various thyroid disorders in pregnancy. Merging clinical evidence with their own professional experience, international experts in the field report on novel research and share insights on a broad range of topics, from addressing the normal physiology of the thyroid in pregnancy, to the safe treatment of disorders during pregnancy.Given its scope, the book is chiefly intended for internists, obstetricians, gynecologists, endocrinologists and related sub-specialists; however, it will also benefit general physicians.

Do you want to know how to integrate environmental, social, and governance (ESG) data into business valuation? This book will help you do so step-by-step.The book primarily aims at reaching two types of audiences: practitioners and students in finance (graduate and undergraduate level). Practitioners in finance will find interest in the book, as it will give them access to academic knowledge in a format that suits them. Academic research has made substantial advances in the field of business valuation and ESG. The book intends to transform this knowledge into practical and rigorous methodologies for taking ESG into account when valuing a company. Graduate and undergraduate courses have recently developed in business schools, universities, and engineering schools. These courses usually directly refer to academic articles or valuation companies' website documentation, but not to academic books. Therefore, the book will allow students to have access to centralized and organized information about business valuation and ESG.Readers without prior knowledge of business valuation will be guided through the ESG integration process. They will first be introduced to the concept of value and the reasons for incorporating ESG into the value. They will then learn simple financial methods to value firms and see step-by-step use cases. For instance, the reader will learn how to value a firm in the renewable energy sector using cash flow and multiple valuation methods. After building knowledge of standard business valuation, readers will better understand ESG data and ratings. The reader will then learn how to integrate ESG into business valuation using cash flow and multiples approaches. Again, the reader will be able to replicate these methods as the book will provide practical cases for integrating ESG data in business valuation. Finally, for the readers that intend to go a bit further, they will learn about the academic research advances in ESG and businessvaluation.

This open access book compares the experiences of large-scale military procurement in Canada and Australia. Focusing on the recent frigate and jet-fighter programmes, it demonstrates how delays suffered in delivering weapons systems and platforms in these countries have been caused by misalignments between the strategic requirements set out by the armed forces and government defence policies. By bringing the insights of public management and administration to those of defence studies, the book presents policy options that will help improve the nature of future large-project military procurement. It will appeal to scholars and students of public administration, public management, and defence studies, as well as practitioners and policymakers.

This book addresses the structural and biological properties of the extracellular matrix component and glycosaminoglycan polymer hyaluronan (or hyaluronic acid, HA).The book discusses various aspects of HA biology, e.g., HA synthesis and degradation, as well as the role of HA in embryogenesis, development, and cell maintenance. The reader will learn about the role of HA in different tissues as well as its biological activities triggered by the interaction with different HA receptors. A closer look is had at the involvement of HA in human pathologies such as cancer, kidney fibrosis and wound healing. Biotechnological and biomedical applications for HA such as scaffold generation and drug delivery, including the novel synthetic sulphated HA are explored.This work will appeal to a wide readership within the extracellular matrix and hyaluronan field. It can serve as an introduction to the field for junior scientists but can also help senior scientists to gain a broader view of the field beyond their area of specialization.The series Biology of Extracellular Matrix is published in collaboration with the American Society for Matrix Biology and the International Society for Matrix Biology.

This book uses Karl Barth¿s Der Römerbrief (1922) as a prism through which to explore the role of religion and its interactions with cultural and political thought in the turbulent interwar period in Europe. One of the most influential books in twentieth-century protestant theology, Der Römerbrief found Barth arguing that the crisis of the time was grounded in an even more profound crisis that pertained to the human condition as such. While much research has been conducted on Der Römerbrief, most of it has focused on the book¿s explicit theology. The aim of the present volume is to mark the centenary of this seminal book with a broader investigation into the movements of thought within Der Römerbrief and its reception and impact within its cultural and intellectual context. This broader approach by a range of Northern European researchers brings attention to interconnections between cultural and theological movements intimes of crisis.

The objective of the book is to adopt the application of data analytics to enhance the sustainability and resilience of the green supply chain networks. To demonstrate the applicability and usefulness of the method, the book adopts different data analytic models and approaches against the backdrop of case studies. In summary, this book attempts to address the question of methods, tools, and techniques that can be used to create resilient, anti-fragile, reliable, and invulnerable green supply chain networks.

The rise of the Internet of Things (IoT) and Artificial Intelligence (AI) leads to the emergence of edge computing systems that push the training and deployment of AI models to the edge of networks for reduced bandwidth cost, improved responsiveness, and better privacy protection, allowing for the ubiquitous AI that can happen anywhere and anytime. Motivated by the above trend, this book introduces a new computing paradigm, the Social Edge Computing (SEC), that empowers human-centric edge intelligent applications by revolutionizing the computing, intelligence, and the training of the AI models at the edge. The SEC paradigm introduces a set of critical human-centric challenges such as the rational nature of edge device owners, pronounced heterogeneity of the edge devices, real-time AI at the edge, human and AI interaction, and the privacy of the edge users. The book addresses these challenges by presenting a series of principled models and systems that enable the confluence of the computing capabilities of devices and the domain knowledge of the people, while explicitly addressing the unique concerns and constraints from humans. Compared to existing books in the field of edge computing, the vision of this book is unique: we focus on the social edge computing (SEC), an emerging paradigm at the intersection of edge computing, AI, and social computing. This book discusses the unique vision, challenges and applications in SEC. To our knowledge, keeping humans in the loop of edge intelligence has not been systematically reviewed and studied in an existing book. The SEC vision generalizes the current machine-to-machine interactions in edge computing (e.g., mobile edge computing literature), and machine-to-AI interactions (e.g., edge intelligence literature) into a holistic human-machine-AI ecosystem.

This book provides a unique, comprehensive, and up-to-date overview of the various NADPH oxidases and narrates the history of their discovery, biochemical characteristics, genetics, molecular structure, and multiple functions in health and disease. It covers the subject in a manner that serves both the expert and the novice researcher in the field.The book starts with an overview of the major milestones in the discovery of the archetypical NADPH oxidase, known as cytochrome b558, and its cytosolic regulators. This is followed by personal recollections by pioneers of the field, descriptions of the work of the major figures of the past by their followers, and a rendering of the history of the discovery of the Nox family. The central section of the book consists of chapters devoted specifically to an in depth description of the individual members of the Nox family, and is followed by chapters focused on the modulators of their function. A subsequent section comprises chapters dealing with methodologies of Nox research, interaction with other proteins, and Nox inhibitors. A distinct section of the book deals with non-mammalian Noxs, from amoeba to zebrafish. Subsequent chapters focus on Nox structure, a field in which extraordinary progress was made in recent years. The volume ends with chapters on Chronic Granulomatous Disease, the consequence of Nox loss-of-function, and its treatment by gene therapy. The coda is a crystal ball perspective of the hopes for the clinical translation of basic Nox research. Written for biochemists, cell biologists, molecular biologists, and clinicians, this book is aimed at both senior scientists and young investigators in the field.

This book focuses on green nanoremediation addressing aspects related to the use of nanomaterials generated through green synthesis protocols to efficiently restore polluted environs. Nanomaterials¿ characteristics such as large surface area, capacity to easily reach into contaminated sites, good reactivity, and possibility of being developed to present photocatalytic activity and/or to deal with targeted substances by chemical surface modification are useful specially to perform remediation. As an alternative to conventional physicochemical methods, the green-based synthesis protocols reject the use of harmful reagents, prevent waste production, apply renewable energy source and/or materials, and consider in first place offering the smallest negative impact possible to living beings and to the ecosystem. Green synthesis in nanotechnology field involves the use of seaweeds, bacteria, cyanobacteria, yeasts, fungi, plants (living ones, biomass, extracts) and/or bio-derived products to generate the nanomaterials. The introductory chapter will be dedicated to nanomaterials¿ characteristics that enable them to be used in environmental remediation. The first part of the book will be dedicated to organic and inorganic pollution and the threats they pose to living forms; advantages, disadvantages and mechanisms of nanoremediation; comparison between conventional strategies of environmental pollution remediation and the green nanoremediation; carbon-based and non-carbon-based green nanomaterials capable of promoting environs¿ remediation; cost/benefits of using nanomaterials and nanoinformatics to a safe nanotechnology. The second part will be dedicated to green nanoremediation of water and soil, microbe-based, algae-based and plant-based synthesis of nanomaterials to nanoremediation. This part will also contain chapters dedicated to relevant nanomaterials for green nanoremediation protocols, nano-phytoremediation strategies, strategies to evaluate the efficiency of protocols related to this kind of remediation, main interactions of green nanomaterials and microbes during nanoremediation and, as a consequence of it, biocompatibility of green nanomaterials. This book¿s main purpose is to offer readers extensive knowledge on green nanoremediation as a feasible strategy to fight pollution's harmful consequences and clean environmental pollution, but also present the challenges that should be surpassed.

This book explores how Canada is imagined primarily by US writers, and what readers and scholars on both sides of the Canada-US border can learn from these recent depictions by examining a selection of US-authored fiction from 9/11 to the present. The novels ¿ and occasionally paintings, films, and musicals ¿ that are the subject of the book provide a deliberately varied set of case studies to probe how US texts, along with works of art produced on both sides of the Canada-US border, uncover moments in Canadian historical and literary studies that have been buried or occluded to protect Canada's self-representation as an exceptional nation.

This volume explores the socio-cultural and media background of a critical and ongoing political challenge: the complex entanglement between European integration and strong national agendas in the context of globalisation. It does so using educational media - both textbooks and digital media - as sites of cultural contestation to enquire into the intricate relationships around national and European identities and aspects of students¿ knowledge and reception. Using a variety of methods and technologies, the chapters analyse identity constructions present in educational media discourses, embedded as they are in their national and European contexts and as both the catalysts and products of their time. The book is a study of the post-digital condition in an educational context, exploring the potential of digital humanities and linguistic approaches for educational media research and employing methods such as eye-tracking or concept maps.

This book, now in an extensively revised third edition, is a superbly illustrated and authoritative reference on tooth wear and its management. Tooth wear is becoming an increasing problem as people are living longer and keeping their teeth for longer, with recent UK surveys showing that at least 75% of adults and more than 50% of children now have some form of identifiable tooth wear. This latest edition addresses this growing challenge by describing practical clinical techniques that will aid identification of the aetiological factors responsible for erosion, attrition and abrasion and by offering guidance in the planning and delivery of appropriate patient care. Readers will find helpful information on difficulties encountered in the diagnosis and prevention of tooth wear, problems associated with controlling the process and strategies for providing management solutions. Alongside thorough updates of the original chapters, this new expanded edition includes several entirely new chapters from highly regarded clinicians and researchers from the UK and Europe. This essential clinical guide will meet the needs of dental professionals and dental students alike.

This Volume 2 of a two-volume work is the first textbook to offer a practical yet comprehensive approach to clinical ophthalmology in wild and exotic mammals.  A phylogenetic approach is used to introduce the ecology and importance of vision across the entire diversity of mammal species before focusing on both the diverse aspects of comparative anatomy and clinical management of ocular disease from one animal group to the next. Edited by three of the most esteemed authorities in exotic animal ophthalmology, this two-volume work is separated into non-mammalian species (Volume 1: Invertebrates, Fishes, Amphibians, Reptiles, and Birds) and Mammals (Volume 2: Mammals).Wild and Exotic Animal Ophthalmology, Volumes 1 and 2 is an essential collection for veterinary ophthalmologists and other veterinary practitioners working with wild and exotic animals.

This book constitutes the refereed proceedings and revised selected papers from the 15th International Symposium on Music in the AI Era, CMMR 2021, which took place during November 15¿19, 2021 as a virtual event. The 24 full papers included in this book were carefully reviewed and selected from 48 submissions. The papers are grouped in thematical sessions on Music technology in the IA era; Interactive systems for music; Music Information Retrieval and Modeling; and Music and Performance Analysis.

This book introduces readers to multicriteria decision aiding (MCDA) interventions used in complex situations. In each chapter, expert analysts propose a piece of the puzzle, while the final, complete puzzle offers an interesting reflection of the main challenges and difficulties associated with decision aiding interventions, as well as the different tools adopted in response. Particular attention is given to the approaches used to identify and overcome specific difficulties.Designed for analysts familiar with several multicriteria methods but seeking detailed information and experience, this book helps to elaborate and validate MC models in real-life decision aiding interventions. In addition, it helps novice analysts appreciate the difficulty of decision aiding and use the available methods to reduce or control them with the help of socio-technical approaches.

Economic efficiency analysis has received considerable worldwide attention in the last few decades, with Stochastic Frontier Analysis (SFA) and Data Envelopment Analysis (DEA) establishing themselves as the two dominant approaches in the literature. This book, by combining cutting-edge theoretical research on DEA and SFA with attractive real-world applications, offers a valuable asset for professors, students, researchers, and professionals working in all branches of economic efficiency analysis, as well as those concerned with the corresponding economic policies. The book is divided into three parts, the first of which is devoted to basic concepts, making the content self-contained. The second is devoted to DEA, and the third to SFA. The topics covered in Part 2 range from stochastic DEA to multidirectional dynamic inefficiency analysis, including directional distance functions, the elimination and choice translating algorithm, benefit-of-the-doubt composite indicators,and internal benchmarking for efficiency evaluations. Part 3 also includes exciting and cutting-edge theoretical research on e.g. robustness, nonparametric stochastic frontier models, hierarchical panel data models, and estimation methods like corrected ordinary least squares and maximum entropy.