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  • 13% sparen
    von Oliver Grillmeyer
    86,00 €

  • von David P. Farrington, Wesley G. Jennings, Alex R. Piquero & usw.
    49,00 €

    This second edition book advances knowledge about criminal careers throughout life. It presents new results from the Cambridge Study in Delinquent Development (CSDD), which is a unique longitudinal study of the development of offending from age 10 to age 61. Previous results obtained in the CSDD are reviewed, and then new findings from official criminal records up to age 61 are presented: on offending at different ages, continuity in offending, ages of onset, and criminal career duration. The number of offenders and offenses between ages 50 and 61 is noteworthy. The book then presents results on self-reported offending in different age ranges up to 48: on prevalence, frequency, continuity, and comparisons with official records that suggest that official records only capture the tip of the iceberg of offending. It then analyzes different trajectories of official offending up to age 61 and shows to what extent they could be predicted by childhood risk factors. New results from the CSDD in the last 10 years are then presented, followed by a discussion of the relevance of all the findings for criminological theories and public policies such as early intervention. This book should be of great interest not only to academics but also to policy makers and practitioners who are concerned with crime. . . . . . . . . . . . . . . . .

  • 13% sparen
    von David J. Brown
    131,00 €

    This volume focuses on games to manage and facilitate rehabilitation. It emphasizes user practice, attitudes, and experience, and their changing place within developing rehabilitation frameworks. It looks at how users have adopted, integrated, and innovated with games to facilitate rehabilitation. Topics include game technology, game design and accessibility, web-based technologies vs pervasive and mobile technologies, social and collaborative aspects, and rehabilitative outcome. Games for rehabilitation are gaining interest from different communities such as medicine, psychology, and rehabilitation. A distinction can be made between games specifically made for rehabilitative purposes and games made for the general public but that are used in rehabilitation as well. Games have allowed the building of new/complementary forms for rehabilitation and offered new options to produce rehabilitative activities and experiences.

  • 12% sparen
    von Margaret J. A. Edwards
    47,00 €

  • 12% sparen
    von Branko Grunbaum
    66,00 - 84,00 €

    "e;The appearance of Grunbaum's book Convex Polytopes in 1967 was a moment of grace to geometers and combinatorialists. The special spirit of the book is very much alive even in those chapters where the book's immense influence made them quickly obsolete. Some other chapters promise beautiful unexplored land for future research. The appearance of the new edition is going to be another moment of grace. Kaibel, Klee and Ziegler were able to update the convex polytope saga in a clear, accurate, lively, and inspired way."e; (Gil Kalai, The Hebrew University of Jerusalem) "e;The original book of Grnbaum has provided the central reference for work in this active area of mathematics for the past 35 years...I first consulted this book as a graduate student in 1967; yet, even today, I am surprised again and again by what I find there. It is an amazingly complete reference for work on this subject up to that time and continues to be a major influence on research to this day."e; (Louis J. Billera, Cornell University) "e;The original edition of Convex Polytopes inspired a whole generation of grateful workers in polytope theory. Without it, it is doubtful whether many of the subsequent advances in the subject would have been made. The many seeds it sowed have since grown into healthy trees, with vigorous branches and luxuriant foliage. It is good to see it in print once again."e; (Peter McMullen, University College London)

  • von Martin Gardner
    34,00 €

  • 15% sparen
    von Victor R. Preedy, Rajkumar Rajendram & Vinood B. Patel
    137,00 €

    Glutamine is the most abundant amino acid and is a major contributor to whole body nitrogen metabolism and is considered to be ¿conditionally essential.¿ Glutamine in Health and Disease presents the application of current nutritional knowledge by physicians and dietitians and incorporates emerging fields of science and important discoveries. Section 1 covers glutamine structure and function, glutamine synthetase, glutamine binding protein, glutamine transport, glutamine-rich activation domains and transcription, glutamine transaminase and cell biochemistry. Section 2 covers glucose-independent glutamine metabolism, intestinal barrier function, thyroid-stimulating hormone, glutamine resonances, focal ischemia, plasma glutamine, metabolic stress, cancer and absorption. Section 3 covers dipeptide-bound glutamine, DNA protection, oxidative stress, NF-KB, the inflammatory response, the lung, kidney, GI tract and liver, autophagy, ethanol and diabetes. Finally, Section 4 covers the use of glutamine in preoperative states, enteral and parenteral nutrition, pulmonary infections, cancer, hypoxic injury, arginyl-glutamine, paediatrics, pancreatic surgery, the elderly, gastric emptying gastric bypass and use glutamine cocktails. Written by authors of international and national standing, leaders in the field and trendsetters, Glutamine in Health and Disease is essential reading for nutritionists and dietitians, public health scientists, physicians, epidemiologists, policy makers, and health care professionals of various disciplines.

  • 11% sparen
    von Masami Tatsuno
    95,00 €

    Since information in the brain is processed by the exchange of spikes among neurons, a study of such group dynamics is extremely important in understanding hippocampus dependent memory. These spike patterns and local field potentials (LFPs) have been analyzed by various statistical methods. These studies have led to important findings of memory information processing. For example, memory-trace replay, a reactivation of behaviorally induced neural patterns during subsequent sleep, has been suggested to play an important role in memory consolidation. It has also been suggested that a ripple/sharp wave event (one of the characteristics of LFPs in the hippocampus) and spiking activity in the cortex have a specific relationship that may facilitate the consolidation of hippocampal dependent memory from the hippocampus to the cortex. The book will provide a state-of-the-art finding of memory information processing through the analysis of multi-neuronal data. The first half of the book is devoted to this analysis aspect. Understanding memory information representation and its consolidation, however, cannot be achieved only by analyzing the data. It is extremely important to construct a computational model to seek an underlying mathematical principle. In other words, an entire picture of hippocampus dependent memory system would be elucidated through close collaboration among experiments, data analysis, and computational modeling. Not only does computational modeling benefit the data analysis of multi-electrode recordings, but it also provides useful insight for future experiments and analyses. The second half of the book will be devoted to the computational modeling of hippocampus-dependent memory.

  • 11% sparen
    von H. Georg Kuhn & Amelia J. Eisch
    95,00 €

    This comprehensive volume is the first to specifically target developing, adult and diseased neural stem cells. It explores recent advances in the understanding of neural stem cell biology along with strategies that use these cells to tackle neurological diseases and brain aging. Ten inclusive chapters discuss a wide range of topics including neurogenesis, neurodegeneration, demyelinating disease, mood regulation, and spinal cord regeneration, among others.Written by world-renowned scientists in the field, Neural Stem Cells in Development, Adulthood and Disease presents cutting-edge studies of interest to both established neurogenesis researchers and readers with general interests in nervous system science. It is an authoritative addition to the Stem Cell Biology and Regenerative Medicine series.

  • 13% sparen
    von Steven A. Kaplan, Bilal Chughtai & Alexis E. Te
    93,00 €

    Treatment of Benign Prostatic Hyperplasia: Modern Techniques is an up-to-date review of modern techniques used to treat benign prostatic hyperplasia. It provides a comprehensive review of both office and operating room based techniques. Both electrosurgical and laser based techniques are covered. These include high powered 532 nm laser photoselective laser vaporization of the prostate (PVP), holmium laser enucleation/ablation of the prostate (HoLEP/HoLAP), and Bipolar Electrovaporization of the Prostate (Bipolar EVP/Bipolar TURP). In addition, a comprehensive review of office based techniques and future therapies currently being developed is presented. Each of these techniques are presented in a balanced fashion with a focus on modern literature. Treatment of Benign Prostatic Hyperplasia: Modern Techniques will be of great value to Urologists, Urology Residents, Iternists, and Family Practitioners. ¿

  • 13% sparen
    von Robert F. Kushner & Daniel H. Bessesen
    93,00 €

    This is a timely and informative updated edition for all health care providers challenged with helping patients manage weight. Similar to the well-reviewed first edition, this updated title is directed toward individuals who wish to read further about targeted topics, rather than find an introduction to the field. This second edition again provides insights into recent scientific advances in obesity research and provides the most up-to-date instruction about current treatment issues and strategies for both adults and children. While several of the chapters are no longer relevant from the first edition, other topics have emerged as interesting and current. This edition will keep the two-section format of Physiology and Pathophysiology and Clinical Management, but it increases the first section to 10 chapters and reduces the second section to 12 chapters. The plan is to keep this edition in the range of about 350 to 400, maximum, printed pages. The volume is again divided into two parts. Part 1 covers new discoveries in the physiological control of body weight, as well as the pathophysiology of obesity. Expert authors discuss pathways that control food intake, energy expenditure and peripheral nutrient metabolism, including a look at the emerging evidence of the role of adipose tissue as an endocrine organ. Part 2 covers all the key issues central to clinical management, including recent developments in the epidemiology of obesity, assessment of the obese patient, behavioral strategies in weight management, dietary modification as a weight management strategy, physical activity as a weight management strategy, weight loss drugs, surgical approaches to obesity and other important clinical topics. An essential, practical text that sorts, synthesizes and interprets the latest information on obesity-related topics, this second edition will be an essential resource for clinical endocrinologists and other health care providers across a broad spectrum of specialties.

  • 10% sparen
    von Jared A. Linebach, Brian P. Tesch & Lea M. Kovacsiss
    48,00 €

    ¿¿Non-parametric methods are widely used for studying populations that take on a ranked order (such as movie reviews receiving one to four stars). The use of non-parametric methods may be necessary when data have a ranking but no clear numerical interpretation, such as when assessing preferences. In terms of levels of measurement, non-parametric methods result in "ordinal" data. As non-parametric methods make fewer assumptions, their applicability is much wider than the corresponding parametric methods. In particular, they may be applied in situations where less is known about the application in question. Also, due to the reliance on fewer assumptions, non-parametric methods are more robust. Non-parametric methods have many popular applications, and are widely used in research in the fields of the behavioral sciences and biomedicine. This is a textbook on non-parametric statistics for applied research. The authors propose to use a realistic yet mostly fictional situation and series of dialogues to illustrate in detail the statistical processes required to complete data analysis. This book draws on a readers existing elementary knowledge of statistical analyses to broaden his/her research capabilities. The material within the book is covered in such a way that someone with a very limited knowledge of statistics would be able to read and understand the concepts detailed in the text.The ¿real world¿ scenario to be presented involves a multidisciplinary team of behavioral, medical, crime analysis, and policy analysis professionals work together to answer specific empirical questions regarding real-world applied problems. The reader is introduced to the team and the data set, and through the course of the text follows the team as they progress through the decision making process of narrowing the data and the research questions to answer the applied problem. In this way, abstract statistical concepts are translated into concrete and specific language.This text uses one data set from which all examples are taken. This is radically different from other statistics books which provide a varied array of examples and data sets. Using only one data set facilitates reader-directed teaching and learning by providing multiple research questions which are integrated rather than using disparate examples and completely unrelated research questions and data.

  • 11% sparen
    von Yuri Suhov & Victor Chulaevsky
    86,00 €

    The study of quantum disorder has generated considerable research activity in mathematics and physics over past 40 years. While single-particle models have been extensively studied at a rigorous mathematical level, little was known about systems of several interacting particles, let alone systems with positive spatial particle density. Creating a consistent theory of disorder in multi-particle quantum systems is an important and challenging problem that largely remains open. Multi-scale Analysis for Random Quantum Systems with Interaction  presents the progress that had been recently achieved in this area.  The main focus of the book is on a rigorous derivation of the multi-particle localization in a strong random external potential field. To make the presentation accessible to a wider audience, the authors restrict attention to a relatively simple tight-binding Anderson model on a cubic lattice Zd.  This book includes the following cutting-edge features: an introduction to the state-of-the-art single-particle localization theory an extensive discussion of relevant technical aspects of the localization theorya thorough comparison of the multi-particle model with its single-particle counterpart a self-contained rigorous derivation of both spectral and dynamical localization in the multi-particle tight-binding Anderson model.  Required mathematical background for the book includes a knowledge of functional calculus, spectral theory (essentially reduced to the case of finite matrices) and basic probability theory. This is an excellent text for a year-long graduate course or seminar in mathematical physics. It also can serve as a standard reference for specialists.

  • von Eliane Regina Rodrigues & Jorge Alberto Achcar
    49,00 €

    ¿In this brief we consider some stochastic models that may be used to study problems related to environmental matters, in particular, air pollution.  The impact of exposure to air pollutants on people's health is a very clear and well documented subject. Therefore, it is very important to obtain ways to predict or explain the behaviour of pollutants in general. Depending on the type of question that one is interested in answering, there are several of ways studying that problem. Among them we may quote, analysis of the time series of the pollutants' measurements, analysis of the information obtained directly from the data, for instance, daily, weekly or monthly averages and standard deviations. Another way to study the behaviour of pollutants in general is through mathematical models. In the mathematical framework we may have for instance deterministic or stochastic models. The type of models that we are going to consider in this brief are the stochastic ones.¿

  • 10% sparen
    von L. Euler
    77,00 €

  • von Ryan J. Warth & Peter J. Millett
    119,00 €

    This text presents a comprehensive and concise evidence-based and differential-based approach to physical examination of the shoulder in a manner that promotes its successful application in clinical practice. Additionally, this book provides an integrated approach to the diagnosis of numerous shoulder pathologies by combining discussions of pathoanatomy and the interpretation of physical examination techniques and was written for any health care professional or student who may be required to evaluate patients who present with shoulder pain. This information will allow the clinician to make informed decisions regarding further testing procedures, imaging and potential therapeutic options.Physical Examination of the Shoulder will serve as an invaluable resource for practicing orthopedic surgeons, sports medicine specialists, physical therapists, residents in training and medical students interested in the field of clinical orthopedics. ¿

  • 15% sparen
    von Mahesh K Shetty
    137,00 €

    This book presents the current trends and practices in breast imaging. Topics include mammographic interpretation; breast ultrasound; breast MRI; management of the symptomatic breast in young, pregnant and lactating women; breast intervention with imaging pathological correlation; the postoperative breast and current and emerging technologies in breast imaging. It emphasizes the importance of fostering a multidisciplinary approach in the diagnosis and treatment of breast diseases. Featuring more than 800 high-resolution images and showcasing contributions from leading authorities in the screening, diagnosis and management of the breast cancer patient, Breast Cancer Screening and Diagnosis is a valuable resource for radiologists, oncologists and surgeons.

  • 14% sparen
    - Total Information Awareness
    von Newton Lee
    74,00 - 79,00 €

    Facebook's psychological experiments and Edward Snowden's NSA leaks epitomize a world of increasing information awareness in the social media ecosystem. With over a billion monthly active users, Facebook as a nation is overtaking China as the largest country in the world. President Barack Obama, in his 2011 State of the Union Address, called America "e;the nation of Edison and the Wright brothers"e; and "e;of Google and Facebook."e; U.S. Chief Information Officer Steven VanRoekel opines that America has become a "e;Facebook nation"e; that demands increased transparency and interactivity from the federal government.Ubiquitous social networks such as Facebook, Google+, Twitter, and YouTube are creating the technologies, infrastructures, and big data necessary for Total Information Awareness - a controversial surveillance program proposed by DARPA after the 9/11 attacks. NSA's secret PRISM program has reinvigorated WikiLeaks founder Julian Assange's accusation that "e;Facebook is the most appalling spying machine that has ever been invented."e;Facebook CEO Mark Zuckerberg once said, "e;We exist at the intersection of technology and social issues."e; This book offers discourse and practical advice on the privacy issue in the age of big data, business intelligence in social media, e-government and e-activism, as well as personal total information awareness. This expanded edition also includes insights from Wikipedian Emily Temple-Wood and Facebook ROI experts Dennis Yu and Alex Houg.

  • von Gregory C. Reinsel, Raja P. Velu & Kun Chen
    95,00 €

  • 15% sparen
    von Paul F. Richardson
    146,00 - 199,00 €

  • von Warren T. Snodgrass
    128,00 €

    Pediatric Urology: Evidence for Optimal Patient Management provides pediatric urologists the information needed for state-of-the-art patient care. Chapters are organized around pertinent clinical questions within major areas of pediatric urology, answered using the best available data while also reporting areas for which there is poor evidence. The text includes randomized controlled trials and prospective observational studies, tables that summarize important studies, and figures that illustrate algorithms with best options for management and their expected results. With an easy to use format not found in other volumes, Pediatric Urology: Evidence for Optimal Patient Management is an indispensible and unique resource for experienced pediatric urologists, pediatric surgeons, general urologists with an interest in pediatric urology, as well as fellows and residents in training.

  • 40% sparen
    von Mohamad Sawan
    549,00 €

    This book provides a broad survey of the field of biochips, including fundamentals of microelectronics and biomaterials interaction with various, living tissues, as well as numerous, diverse applications. Although a wide variety of biochips will be described, there will be a focus on those at the brain-machine interface. Analysis is included of the relationship between different categories of biochips and their interactions with the body and coverage includes wireless remote control of biochips and arrays of microelectrodes, based on new biomaterials.

  • von Sana Loue
    775,00 €

    There is increasing interest in the scientific literature on immigrant health and its impact on disease transmission, disease prevention, health promotion, well-being on an individual and population level, health policy, and the cost of managing all these issues on an individual, institutional, national, and global level. The need for accurate and up-to-date information is particularly acute due to the increasing numbers of immigrants and refugees worldwide as the result of natural disasters, political turmoil, the growing numbers of immigrants to magnet countries, and the increasing costs of associated health care that are being felt by governments around the world.Format and Scope: The first portion of the encyclopedia contains chapters that are approximately 25 to 40 manuscript pages in length. Each overview chapter includes a list of references and suggested readings for cross referencing within the encyclopedia. The opening chapters are: Immigration in the Global Context, Immigration Processes and Health in the U.S.: A Brief History, Alternative and Complementary Medicine, Culture-Specific Diagnoses, Health Determinants, Occupational and Environmental Health, Methodological Issues in Immigrant Health Research, Ethical Issues in Research with Immigrants and Refugees, Ethical Issues in the Clinical Context.The second portion of the book consists of alphabetical entries that relate to the health of immigrants. Entries are interdisciplinary and are drawn from the following fields of study: anthropology, demographics, history, law, linguistics, medicine, population studies, psychology, religion, and sociology. Each entry is followed by a listing of suggested readings and suggested resources, and also links to related terms within the whole book. Outstanding FeaturesThe book adopts a biopsychosocial-historical approach to the topics covered in the chapters and the entries. Each entry includes suggested readings and suggested resources. The chapters and entries are written graduate level that is accessible to all academics, researchers, and professionals from diverse backgrounds. We consider the audience for the entries to be well educated, but a non expert in this area. The primary focus of the book is on the immigrant populations in and immigration to magnet countries. References are made to worldwide trends and issues arising globally.In addition to the comprehensive subject coverage the text also offers diverse perspectives. The editors themselves reflect the multidisciplinary nature of the topics, with expertise in psychiatry, law, epidemiology, anthropology, and social work. Authors similarly reflect diverse disciplines.

  • 15% sparen
    von Dieter Jäger
    1.999,00 €

    The annual Computational Neuroscience Meeting (CNS) began in 1990 as a small workshop called Analysis and Modeling of Neural Systems. The goal of the workshop was to explore the boundary between neuroscience and computation. Riding on the success of several seminal papers, physicists had made "e;Neural Networks"e; fashionable, and soon the quantitative methods used in these abstract model networks started permeating the methods and ideas of experimental neuroscientists. Although experimental neurophysiological approaches provided many advances, it became increasingly evident that mathematical and computational techniques would be required to achieve a comprehensive and quantitative understanding of neural system function. "e;Computational Neuroscience"e; emerged to complement experimental neurophysiology. The Encyclopedia of Computational Neuroscience, published in conjunction with the Organization for Computational Neuroscience, will be an extensive reference work consultable by both researchers and graduate level students. It will be a dynamic, living reference, updatable and containing linkouts and multimedia content whenever relevant.

  • 14% sparen
    von Dimitris Charalampopoulos
    549,00 €

    A comprehensive overview on the advances in the field, this volume presents the science underpinning the probiotic and prebiotic effects, the latest in vivo studies, the technological issues in the development and manufacture of these types of products, and the regulatory issues involved. It will be a useful reference for both scientists and technologists working in academic and governmental institutes, and the industry.

  • von Caio Maximino
    49,00 €

    Anxiety disorders have long been a research subject for scientists in different areas of inquiry, and the particular role of serotonin ¿ the neurotransmitter which has probably most captured the imagination of laymen and academics alike ¿ is as elusive as the clinical aspects of serotonergic medications. Why are drugs acting at certain serotonin receptors efficacious against generalized anxiety disorder, but not panic disorder? Why is the inverse true for monoamine oxidase inhibitors? These clinically relevant issues are clarified by the neurochemical, anatomical and physiological organization of the serotonergic system.In this book, the author summarizes the latest findings regarding the role of serotonin in modulating the activity of brain regions which organize behavioral patterns associated with fear, anxiety and stress. The emergent picture is one of far greater complexity than previously thought: while the serotonergic innervation of those brain regions arises from the same structure ¿ the dorsal raphe nucleus ¿ that structure is not homogeneous from anatomical, physiological and neurochemical points of view, nor are its projections to the cerebral aversive and behavioral inhibition systems.The diverse findings which compose this picture of complexity ¿ whether they arise from developmental neurobiology, electrophysiology, neurochemistry, neuroendocrinology, neuropsychopharmacology or behavioral neuroscience ¿ are integrated in this book. Advanced undergraduate, graduate students, and researchers will benefit from the information. The result sheds light on many important questions regarding the neuroanatomical, pharmacological and functional aspects of the role of serotonin in anxiety disorders, and points to future avenues of research.

  • von John G. Brock-Utne
    53,00 €

    This book provides insights into how to be a productive clinical researcher via real-life case examples of successful clinical research -- and also clinical research gone awry. Through these examples of success and failure, the book develops a blueprint for building a career in clinical research. Future medical practice depends on the quality of the clinical trials to which drugs, devices, and treatment procedures are subjected today. However, clinical trials are not easy to do, and many physicians and health care providers who attempt clinical research struggle in this endeavor, primarily because of lack of instruction. Clinical Research aims to fill the gap between training and research through case studies of a long-time clinical researcher's rich and varied experiences.

  • 13% sparen
    von Xiaolin Li & Judy Qiu
    93,00 €

    This book presents a range of cloud computing platforms for data-intensive scientific applications. It covers systems that deliver infrastructure as a service, including: HPC as a service; virtual networks as a service; scalable and reliable storage; algorithms that manage vast cloud resources and applications runtime; and programming models that enable pragmatic programming and implementation toolkits for eScience applications. Many scientific applications in clouds are also introduced, such as bioinformatics, biology, weather forecasting and social networks. Most chapters include case studies.Cloud Computing for Data-Intensive Applications targets advanced-level students and researchers studying computer science and electrical engineering. Professionals working in cloud computing, networks, databases and more will also find this book useful as a reference.

  • 11% sparen
    von Victor R. Preedy, Rajkumar Rajendram & Vinood B. Patel
    95,00 €

    This is the second volume in a 2-volume compendium that is the go-to source for both research- and practice-oriented information on the importance of branched chain amino acids in maintaining the nutritional status and overall health of individuals, especially those with certain disease conditions.  Over 150 well recognized and respected contributors have come together to compile these up-to-date and well-referenced works. The volumes will serve the reader as the benchmarks in this complex area of interrelationships between dietary protein intakes and individual amino acid supplementation, the unique role of the branched chain amino acids in the synthesis of brain neurotransmitters, collagen formation, insulin and glucose modulation and the functioning of all organ systems that are involved in the maintenance of the body's metabolic integrity.  Moreover, the physiological, genetic and pathological interactions between plasma levels of branched chain amino acids and aromatic amino acids are clearly delineated so that students as well as practitioners can better understand the complexities of these interactions.Branched Chain Amino Acids in Clinical Nutrition: Volume 2 covers the role of branched chain amino acids in healthy individuals, and branched chain amino acid status in disease states, liver diseases, and supplementation studies in certain patient populations.

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