Bücher veröffentlicht von Springer Verlag, Japan

This book provides the current updated knowledge on all essential aspects in the rapidly evolving area of Helicobacter pylori research. pylori will remain asymptomatic, up to 20 % of them may develop serious gastroduodenal disease such as peptic ulcers or gastric cancer.

This volume provides a comprehensive summary of glycosignals and their involvement in cancer, covering numerous topics such as glycosylation machineries, regulation of phenotypes, cell signaling, immune regulation, complex carbohydrate organization, and clinical applications.

This work is devoted to understanding the recent advances in nuclear medicine and molecular imaging technologies along with their application to integrated medical therapy and future drug development.

This book is highly suitable for advanced courses asit introduces state-of-the-art information and the latest research results ondiverse problems in the environmental wind engineering field.

This book provides all facets of acetic acid bacteria (AAB) and offers the future targets and directions of AAB research.

This book focuses on standard operative techniques for important diseases in pediatric surgery, especially in neonates and infants, while also offering a wealth of schematic drawings and photographs to help readers understand the surgical techniques.

This book comprises 7 parts and 21 chapters: Part 1 (Chapters 1-3), DNA Replication;

Going from the philosophy and concepts to the implementation and user study, this book presents an excellent overview of Japan's contemporary technical challenges in the field of human-computer interaction. The next information era will be one in which information is used to cultivate human and social potential. Driven by this vision, the outcomes provided in this work were accomplished as challenges to establish basic technologies for achieving harmony between human beings and the information environment by integrating element technologies including real-space communication, human interfaces, and media processing. Ranging from the neuro-cognitive level to the field trial, the research activities integrated novel perceptual technologies that even exceed human ability to sense, capture, and affect the real world.This book grew out of one of the CREST research areas funded by the Japan Science and Technology Agency. The theme of the project is "the creation of human-harmonized information technology for convivial society", where 17 research teams aimed at a common goal. The project promotes a trans-disciplinary approach featuring (1) recognition and comprehension of human behaviors and real-space contexts by utilizing sensor networks and ubiquitous computing, (2) technologies for facilitating man-machine communication by utilizing robots and ubiquitous networks, and (3) content technologies for analyzing, mining, integrating, and structuring multimedia data including those in text, voice, music, and images.This is the first of two volumes, which is contributed by nine team leaders. Besides describing the technical challenges, each contribution lays much weight on discussing the philosophy, concepts, and the implications underlying the project. This work will provide researchers and practitioners in the related areas with an excellent opportunity to find interesting new developments and to think about the relationship between human and information technology.

This book reviews the role of each cell subset in the skin, providing the basics for understanding skin immunology and the mechanisms of skin diseases.

This volume presents detailed information on surgically relevant anatomy and histology of the anterior cruciate ligament (ACL), biomechanics, diagnostics, and ACL reconstruction.

This book provides a useful overall guide to the state of the art in theory and practice of services. This book helps readers to understand serviceology, which tackles with a broad range of services, the globalization of the economy and also enhances the quality of life of local residents.

In this monograph, the importance of fluctuations forbiological reactions is discussed from various points of view. Scientists in a number of fields-physics,chemistry, pharmacology, medicine, and others-have contributed chapters thatelucidate the nature of the fluctuations and the relationship betweenfluctuations and biological functions.

This book overviews environmental issues 4 years after the Fukushima nuclear accident, covering a wide range of areas related to radiation and radioactivity. The topics discussed are necessary to make clear the relationship between the results of research and Fukushima's revitalized future. The chapters are divided into four parts: Part 1 presents the identification of radionuclides in soil and migration of radionuclides in the terrestrial environment; Part 2 describes the safety decontamination system and treatment of radioactive waste; Part 3 explains the development of the system of measurement of environmental radiation and evaluation of external exposure; and Part 4 discusses the identification of radionuclides in farm products, control of root uptake, identification of decreasing radionuclides by food processing, and evaluation of internal exposure. Since the accident at the Tokyo Electric Power Company's Fukushima Daiichi nuclear power station in 2011, gradual steps have been taken toward environmental recovery in the area. However, there are still many issues that need to be tackled in order to achieve the full revitalization of Fukushima. These issues encompass many different disciplines such as economics, psychology, and sociology. In this kind of situation, the role of science in relation to radiation and radioactivity is especially important. This book aims to contribute to planning countermeasures against nuclear disasters in the future. It will be of particular interest to governmental officials who are engaged with the Fukushima nuclear accident; researchers, including those in international sectors, who are interested in radiological issues; and those who need comprehensive and reliable information about the Fukushima accident.

Therefore, HSF is now thought to be a promising therapeutic target for treatment of these refractory diseases. For undergraduate students, this is a highly understandable source of information on heart shock response and HSF, covering the basis of HSF biology, the physiological role of HSF, and disease associated with HSF function.

This book presents basic and extensive information on the physiological and pathological significance of the protein-modifying enzymes, transglutaminases, which are involved in multiple biological events by catalyzing a unique and important posttranslational modification reaction, cross-linking of proteins, and interacting with a large number of proteins inside and outside of cells. Although several of their essential physiological roles have been revealed, many unknown and so far not fully understood functions have remained. In humans, there are eight active isozymes having distinct tissue and subcellular distribution patterns with different substrates and physiological roles. Accordingly, aberrant regulation of the enzyme reactions or expression may lead to or has been implicated in various pathologies including neurodegeneration, fibrosis, cancer, inflammation, celiac disease, and hemostasis disorders.To provide those who are new to the field with basic knowledge and recent information on transglutaminase structures and reactions, the mechanism by which transglutaminases modify substrate proteins and their contributions to multiple biological phenomena as well as disease phenotypes, the publication of the present transglutaminase book was planned, to consist of review articles by 17 expert investigators working in this exciting area of research. The book contains detailed information related to several transglutaminases from aspects in chemical and cellular biology, medical sciences, and biotechnology that will also supply starting points for drug discovery. Although many prominent findings have been published in recent years, this type of comprehensive review book has been missing in the scientific literature. This volume will be useful for investigators who either currently work on or will start addressing transglutaminase-related research, and beyond that, for a broad audience in the scientific community.

This book reports the results from on-site research into radioactive cesium contamination in various agricultural systems affected by the Fukushima Daiichi Nuclear Power Plant accident that occurred in March 2011.

This book covers diverse environmental issues such as climate change; Each chapter of this book corresponds to a lecture in the East Asia Environmental Strategist Training Program at Kyushu University and is excellent reading as a sourcebook.

This book covers seismic probabilistic risk assessment (S-PRA) and related studies which have become more important to increase the safety of nuclear facilities against earthquakes and tsunamis in the face of the many uncertainties after the Fukushima accident.

This book is a methodological source on mice models of vascular diseases. Genetically modified mice are a very powerful tool for studying the pathogenesis of various diseases, including immunological and oncological disorders, but they had always been thought to be too small to be used in the field of cardiovascular disease.

It is ideal for researchers starting work in this field in that it provides a quick update on present-day basic neurolaryngology. The book contains much general material that will be instructive even for researchers not specializing in basic neurolaryngology and will provide an essential grounding for clinicians in laryngology.

This book examines the state of the art in diverse areas of haptics (touch)-related research, including the psychophysics and neurophysiology of haptics, development of haptics displays and sensors, and applications to a wide variety of fields such as industry, education, therapy, medicine, and welfare for the visually impaired.

Based on the results of studies on autoimmunity, the endocrine system, nutrients, metal metabolism and intestinal bacterial flora, this volume thoroughly covers studies on functional correlation of the liver with the spleen, visceral fat, intestinal tract, and central nervous system.

As either bone or muscle is intimately involved in the regulation of metabolic status, keeping the musculoskeletal system healthy is important for improving abnormal glucose metabolism toward normal levels and is vital, as well, for maintaining normal activities of daily living.

Featuring contributions from prominent experts in the fields, the book focuses on the current status of the application of MEG, not only to each nervous system but also to various diseases such as epilepsy, neurological disorders, and psychiatric disorders, while also examining the feasibility of using MEG for these diseases.

This book provides a comprehensive review of the recent advances in the research of systemic sclerosis (scleroderma). Systemic sclerosis is a complex autoimmune disease characterized by vasculopathy, fibrosis, and immune activation. Recent studies have revealed a variety of new evidence suggestive of the pathogenesis of the disease.

This book provides simplified principles of surgical anatomy for colorectal cancers with sophisticated drawings, standard laparoscopic procedures with striking photographs and illustrations, and advanced procedures such as lateral pelvic node dissection and "down to top" or "reverse" total mesorectal excision.Oncological safety as well as minimum invasiveness of laparoscopic surgery for colorectal cancer has been acknowledged worldwide, based on long-term outcomes of several randomized controlled trials comparing laparoscopic surgery and open surgery. Developments in optical devices have provided us with a magnified clear vision of fine anatomical structures, facilitating our understanding of surgical anatomy and surgical procedures have been refined and improved accordingly.All these topics are presented in this book-valuable for surgical residents and experts eager to learn more about laparoscopic colorectal surgery-and readers will be enlightened by a new paradigm for "lap-enhanced surgical anatomy". Therefore this volume will greatly benefit not only colorectal surgeons but also general surgeons as well as gastroenterologists and oncologists.

In this book, recognized anesthesiology experts present the latest findings on anesthesia for electro-convulsive therapy (ECT).

This book presents recent advances in translational research on muscular dystrophy (MD) to physicians and researchers, including cutting-edge research on the disease such as regenerative medicine, next-generation DNA sequencing, and nucleic acid therapies.

This book offers a detailed review of the pathological and imaging features, diagnosis and treatment of IgG4-Related Kidney Disease (IgG4-RKD). IgG4-related disease (IgG4-RD), which is characterized by an elevated serum IgG4 level and infiltration of systemic organs by IgG4 positive plasma cells, is a newly recognized systemic disease.

This book reviews the brilliant progress made in the past three decades in clinical outcomes for osteosarcoma patients treated with a multidisciplinary approach, including limb-salvage surgery combined with neoadjuvant multidrug chemotherapy and aggressive management of pulmonary metastasis.