Bücher veröffentlicht von Springer Verlag, Japan

This book provides a detailed review of the most recent pathogenetic, diagnostic and therapeutic approaches in connection with Helicobacter pylori, along with priority areas in research and trends in clinical practice to address this significant pathogen acknowledged as the causative agent in a wide range of diseases, including gastric adenocarcinoma, MALT lymphoma and immune thrombocytopenic purpura (ITP). Medical authorities worldwide now recommend a "test and treat" strategy for this bacterial infection. Eradication therapy approaches range from general mass eradication therapy to tailor-made therapy for antibiotic-resistant refractory infection. In regions with high prevalence of H. pylori infection, the infection itself would be considered a major parameter to predict the risk of gastric adenocarcinoma development. The main interest has shifted recently to the risk stratification strategy for gastric cancer development and to the wide-ranging application of its serological prevention program.This book will benefit all gastroenterologists, hematologists, dermatologists, primary care doctors, epidemiologists, physicians who related with community hygiene, as well as basic scientists, particularly microbiologists, bacteriologists, pathologists, molecular biologists, biochemists, immunologists and oncologists.

It has enabled those economies to exploit new possibilities of further development, which may mean a new stage of manufacturing cum services in an ICT- and knowledge-based economy.

This book deals with the essential factors in the personalization of treatment for primary breast cancer.

This book discusses the latest findings on the pathogenesis and treatment of IgA nephropathy. It particularly focuses on recently recognized initiation and progression factors and the varying treatment strategies in different regions, such as Asia, Europe, and the United States. More than 40 years have passed since Dr. Jean Berger first described primary IgA nephropathy ("Nephropathy with mesangial IgA-IgG deposits") as a new disease entity.Immunohistopathologically, IgA nephropathy is characterized by the granular deposition of IgA (IgA1) and C3 in the glomerular mesangial areas with mesangial cell proliferation and the expansion of mesangial matrices. It is clear that IgA nephropathy is one of the most common types of chronic glomerulonephritis in the world. This disease may lead to end-stage kidney disease, with its enormous economic impact on healthcare everywhere. Efforts by many investigators around the world have gradually clarified various aspects of the pathogenesis and treatment of IgA nephropathy. However, there are many controversial strategies for the treatment of patients with IgA nephropathy throughout the world, as there are several limitations for treatment in each country. This volume provides nephrologists everywhere with an overview and comparison of both global and regional findings in basic and clinical fields in IgA nephropathy. It covers genetic variation, aberrant IgA1 production, and classification etiology, guidelines, and treatment goals, with all chapters written by top international researchers.

This book offers a detailed review of the remarkable advances that have been made in research on the pathogenesis of a number of neuroimmunological diseases, as well as outlining novel treatments including the use of monoclonal antibodies. Written by renowned experts who have made major contributions in the field, such as identifying neuromyelitis optica as an immunopathological clinical condition, identifying the role of ganglioside and ganglioside-complex antibodies in Guillain-Barré syndrome, and developing a novel treatment for POEMS (polyneuropathy, organomegaly, endocrinopathy, M-protein, and skin changes) syndrome, the book summarizes recent advances in basic and clinical research. Neuroimmunological Diseases is a useful resource for not only researchers but also neurologists who are engaged in the management of neuroimmunological diseases.

Reading this book will lead to new insights compelling to an international audience into how cities address the sustainability challenges they face.

This book presents a comprehensive overview and outlook for the future of indocyanine green (ICG) fluorescence navigation surgery, which is attracting clinical interest as a safe and less invasive procedure not only in detecting cerebral vessels, coronary arteries, and biliary trees, but also in identifying sentinel lymph nodes in cancer.

This book provides a comprehensive review of diagnosis and treatments of renal cell carcinoma (RCC) for practitioners and researchers with an interest in this disease. A major aim of the book is to present the most important and most recent advances in molecular bases and targeted therapy for this neoplasm. The remarkable resistance to chemotherapy and radiotherapy and the minimum contribution of cancer genes that commonly mutate in other adult epithelial cancers have made RCC highly distinct from other types of solid neoplasms. In the past decade, however, treatment options for RCC have been expanding and moving quickly toward laboratory-based and molecular-targeted therapies. Advances in RCC therapy also have brought novel treatment options to other types of cancer, such as a TKI for hepatocellular carcinoma and gastrointestinal tumors, as well as mTOR inhibitors to progressive neuroendocrine tumors of pancreatic origin and to breast cancer, suggesting that RCC is no longer an "orphan disease" in the field of molecular oncology. Additional topics covered in the book include pharmacokinetics and pharmacodynamics in molecular-targeted agents and the putative mechanism of resistance to anti-angiogenic agents, such as intratumoral heterogeneity or cancer stem cell population. This volume provides the latest and most useful information for all readers who are eagerly devoted to curing renal cell carcinoma.

Since the production of many low-cost man-made fibers shifted to China and other Asian countries, Japanese companies have focused on production of high-quality, high-performance super fibers as well as highly functionalized fibers so-called 'Shin-gosen'.

This book describes the fundamental biology and mechanics of the vasculature and examines how this knowledge has underpinned the development of new clinical modalities, including endovascular treatment and vascularization of reconstructed tissue for regenerative medicine.

This timely book, published just as cancer immunotherapy comes of age, summarizes the rationale, present status, and future perspective for cancer immunotherapy.

This book is intended fornon-destructive testing (NDT) technicians who want to learn practical acousticemission testing based on level 1 of ISO 9712 (Non-destructive testing -Qualification and certification of personnel) criteria.

Volume B describes to what extent cognitive science and neuroscience have revealed the underlying mechanism of human cognition, and investigates how development of neural engineering and advances in other disciplines could lead to deep understanding of human cognition.

This volume focuses on the etiology and morphogenesis of congenitalheart diseases.

Volume A describes how human cognitive functions can be replicated in artificial systems such as robots, and investigates how artificial systems could acquire intelligent behaviors through interaction with others and their environment.

Covering the history of breast cancer, theory of radiofrequency ablation (RFA), resection of carcinoma, imaging before and after non-surgical ablation therapy and quality of life, this book focuses on extensive breast-conserving treatment for the preservation of a cosmetically acceptable breast.

This book focuses on the preoperative diagnosis of early-stage gastric cancer, presenting various cases and their diagnoses using Endoscopic Submucosal Dissection (ESD), a new technique for dissecting early-stage gastric cancer.

This book aims to illuminate coral reefs which comprise a symbiotic system coexisting among ecosystems, landforms, and humans at various levels and to provide a scientific basis for its reconstruction.

This book presents the "New Vision 2050," which adds the concept of the "platinum society" to the "Vision 2050". The 20th century was a century in which energy led the development of material civilization, resulting in deletion of resources, global warming and climate change.

The essence of natural computing is aesthetics; Because touch perception is instinctively related to a sense of beauty, the aesthetics of tactile sense are considered as algorithms by using the Tactile Score, which encodes tactile sensation.

This book describes how biologically available free energy sources (ATP, chemical potential, and membrane potentials, among others) can be used to drive synthetic reactions, signaling in cells, and various types of motion such as membrane traffic, active transport, and cell locomotion.

Filled with illustrations drawn from the surgeon's point of view, it the book will be useful not only to surgeons and students but also to paramedical personnel. These kind of modifications will become useful resources to surgeons in some part of world where the homograft is not available.

To manage fungicide resistance successfully will require the promotion of integrated disease management, involving not just chemical fungicides, but also host plant resistance, agronomic factors, and reliable biological control agents where these are available.

It is against this background and in recognition of the importance and urgency of the problem that this book brings together new insights on the topic together with research published to date.

A new era for liver anatomy has dawned. Liver anatomy has since been reevaluated from the standpoint of portal segmentation and drainage veins and includes a reclassification of the liver.

The authors are specialists in macroeconomics, public economics, environmental economics, transportation economics and spatial economics, all of which are important aspects of regional science.

This book sheds new light on neurodegenerative disorders as systemic diseases. This book will be of interest to both researchers and medical personnel, and provides a fresh approach to neurodegenerative diseases, paving the way to new research and improved quality of health care for patients.

This book is a knowledge-based text that covers the anatomy, neurophysiology, and neuropharmacology needed to carry out the necessary management and cerebrospinal protection during neuroanesthesia.