Bücher veröffentlicht von Springer Verlag, Singapore

This book explains both the basic science and the applications of biotechnology-derived pharmaceuticals, with special emphasis on their clinical uses. The foundations of pharmaceutical biotechnology lie mainly in the capability of plants, microorganism, and animals to produce low and high molecular weight compounds useful as therapeutics. Pharmaceutical biotechnology has flourished since the advent of recombinant DNA technology and metabolic engineering, supported by the well-developed bioprocess technology. A large number of monoclonal antibodies and therapeutic proteins have been approved, delivering meaningful contributions to patients¿ lives, and the techniques of biotechnology are also a driving force in modern drug discovery. Due to this rapid growth in the importance of biopharmaceuticals and the techniques of biotechnologies to modern medicine and the life sciences, the field of pharmaceutical biotechnology has become an increasingly important component in the educationof pharmacists and pharmaceutical scientists. This book will serve as a complete one-stop source on the subject for undergraduate and graduate pharmacists, pharmaceutical science students, and pharmaceutical scientists in industry and academia.

This book provides an in-depth investigation of citizenship and nationalism in connection with the Rohingya community. It analyses the processes of production of statelessness in South Asia in general, and with regard to the Rohingyas in particular. Following the persecution of the Rohingya community in Myanmar (Burma) by the military and the Buddhist militia, a host of texts, mostly descriptive, have examined the historical, political and cultural roots of the genocidal massacre and the flight of its victims to South Asia and South-East Asian countries. The UNHCR reports describe the plight of Rohingyas during and after their journey, while other works focus on the political-economic roots of this ethnic conflict and its consequences for the Rohingyas. To date, very few theoretical insights have been provided on the Rohingya issue. This book seeks to fill that gap, and explores a dialogue between the state and its citizens and non-citizens that results in theproduction of statelessness. In theoretical terms, the book addresses the construction of citizens and non-citizens on the part of the state, and the process of symbolic othering, achieved through various state practices couched in terms of nationalism. Extensive case studies from India, Myanmar and Bangladesh provide the foundation for a robust theoretical argument. Given its scope, the book will be of interest to students, academics and researchers with a focus on political economy in South Asia in general and/or refugee studies in particular.

This book presents nature inspired computing applications for the wireless sensor network (WSN). Although the use of WSN is increasing rapidly, it has a number of limitations in the context of battery issue, distraction, low communication speed, and security. This means there is a need for innovative intelligent algorithms to address these issues.The book is divided into three sections and also includes an introductory chapter providing an overview of WSN and its various applications and algorithms as well as the associated challenges. Section 1 describes bio-inspired optimization algorithms, such as genetic algorithms (GA), artificial neural networks (ANN) and artificial immune systems (AIS) in the contexts of fault analysis and diagnosis, and traffic management. Section 2 highlights swarm optimization techniques, such as African buffalo optimization (ABO), particle swarm optimization (PSO), and modified swarm intelligence technique for solving the problems of routing,network parameters optimization, and energy estimation. Lastly, Section 3 explores multi-objective optimization techniques using GA, PSO, ANN, teaching¿learning-based optimization (TLBO), and combinations of the algorithms presented. As such, the book provides efficient and optimal solutions for WSN problems based on nature-inspired algorithms.

¿This book discusses essential strategies and approaches to creating mentally restorative environments for highly stressed and depressed workers at sweatshop factories. Drawing on the Foxconn factory in Longhua, China and an adjacent urban village as a sample site for research and design practice, the book employs a bottom-up and participatory process. The content is divided into two main parts, the first of which investigates economic, cultural, human rights, and environmental issues related to the electronic industry and urban village, providing in-depth research on various aspects, especially the working and living conditions for Foxconn workers. Based on these findings, the second part highlights potential landscape designs to address a range of issues, locations, and scales. The book¿s goals are to provide a set of original methods for research and design practice in a complex social and economic context, and to raise awareness regarding the health, dignity and freedom of millions of workers.

Soil analysis is critically important in the management of soil-based production systems. In the absence of efficient methods of soil analysis our understanding of soil is pure guesswork. Ideally the pro-active use of laboratory analysis leads to more sustainable soil productivity. Unfortunately, most of the world¿s agriculture is still reactionary, waiting for obvious yield declines to occur before taking action to identify the reasons. The modern soil laboratory is pivotal to informing soil managers what adaptive practices are needed to address chemical and physical imbalances before they occur, and the intelligent adaptive use of laboratory data not only greatly speeds up and reduces the cost of empirical soil study, but can even render it unnecessary.This book provides a synopsis of the analytical procedures used for soil analysis, discussing the common physical, chemical and biological analytical methods used in agriculture and horticulture. Writtenby experienced experts from institutions and laboratories around the globe, it provides insights for a range of users, including those with limited laboratory facilities, and helps students, teachers, soil scientists and laboratory technicians increase their knowledge and skills and select appropriate methods for soil analysis.

Plants produce a vast number of bioactive compounds with different chemical scaffolds, which modulate a diverse range of molecular targets and are used as drugs for treating numerous diseases. Most present-day medicines are derived either from plant compounds or their derivatives, and plant compounds continue to offer limitless reserves for the discovery of new medicines. While different classes of plant compounds, like phenolics, flavonoids, saponins and alkaloids, and their potential pharmacological applications are currently being explored, their curative mechanisms are yet to be understood in detail. This book is divided into 2 volumes and offers detailed information on plant-derived bioactive compounds, including recent research findings. Volume 1, Plant-derived Bioactives: Chemistry and Mode of Action, discusses the chemistry of highly valued plant bioactive compounds and their mode of actions at the molecular level. Volume 2, Plant-derived Bioactives: Production, Properties and Therapeutic Applications, explores the sources, biosynthesis, production, biological properties and therapeutic applications of plant bioactives. Given their scope, these books are valuable resources for members of the scientific community wishing to further explore various medicinal plants and the therapeutic applications of their bioactive compounds. They appeal to scholars, teachers and scientists involved in plant product research, and facilitate the development of innovative new drugs.

¿Microbial Enzymes: Roles and applications in industry¿ offers an essential update on the field of microbial biotechnology, and presents the latest information on a range of microbial enzymes such as fructosyltransferase, laccases, amylases, lipase, and cholesterol oxidase, as well as their potential applications in various industries. Production and optimisation technologies for several industrially relevant microbial enzymes are also addressed.In recent years, genetic engineering has opened up new possibilities for redesigning microbial enzymes that are useful in multiple industries, an aspect that the book explores. In addition, it demonstrates how some of the emerging issues in the fields of agriculture, environment and human health can be resolved with the aid of green technologies based on microbial enzymes. The topics covered here will not only provide a better understanding of the commercial applications of microbial enzymes, but also outline futuristic approaches to usemicrobial enzymes as driver of industrial sustainability.Lastly, the book is intended to provide readers with an overview of recent applications of microbial enzymes in various industrial sectors, and to pique researchers¿ interest in the development of novel microbial enzyme technologies to meet the changing needs of industry.

¿Microbial Enzymes: Roles and applications in industry¿ offers an essential update on the field of microbial biotechnology, and presents the latest information on a range of microbial enzymes such as fructosyltransferase, laccases, amylases, lipase, and cholesterol oxidase, as well as their potential applications in various industries. Production and optimisation technologies for several industrially relevant microbial enzymes are also addressed.In recent years, genetic engineering has opened up new possibilities for redesigning microbial enzymes that are useful in multiple industries, an aspect that the book explores. In addition, it demonstrates how some of the emerging issues in the fields of agriculture, environment and human health can be resolved with the aid of green technologies based on microbial enzymes. The topics covered here will not only provide a better understanding of the commercial applications of microbial enzymes, but also outline futuristic approaches to use microbial enzymes as driver of industrial sustainability.Lastly, the book is intended to provide readers with an overview of recent applications of microbial enzymes in various industrial sectors, and to pique researchers¿ interest in the development of novel microbial enzyme technologies to meet the changing needs of industry.