Bücher veröffentlicht von Springer Verlag, Singapore

The book covers all aspects of eye health in South-East Asia from public health to health system to education to industry in 6 sections. The World Health Organization (WHO) South-East Asia region comprises of 11 countries - Bangladesh, Bhutan, DPR Korea, India, Indonesia, Maldives, Myanmar, Nepal, Sri Lanka, Thailand and Timor-Leste. This region is home to 26% of world population; there is a disproportionate amount of blindness (30.6%) and visual impairment (36%).This is a first of its kind book that discusses common conditions of visual impairment and blindness in the South-East Asia region. In addition, the book documents the current eye care industry in the region and the contribution of all eye health INGOs in eye care program planning and service delivery for many decades. Majority of the countries in the South-East Asia region are categorized in ¿middle-income country¿ group. This book discusses the common challenges in these countries such as, suboptimal public expenditure in health, acute shortage of skilled eye health workforce, and rudimentary health industry. The book covers the following 6 sections:1. Geographic description and health indices of the region2. Health system evolved over years, including universal eye health, health financing and health management information system (HMIS)3. Common eye problems including non-communicable disease NCD (and diabetic retinopathy), neglected tropical disease NTD (and Trachoma)4. Health workforce in the region that includes ophthalmologists, optometrists, and allied ophthalmic personnel5. Eye health support in the region of 13 international non-government organizations (INGOs) working for decades6. Eye health industry in the region that includes spectacles, ophthalmic devices and equipment and the pharma industry The book would be a useful resource for ophthalmologists, all public health personnel and policy makers in eye health in the South-East Asia region specifically and all ophthalmologists and scientists interested in public health all over the world as well as for program planning to reach the 'Health for All' strategy by 2030 (United Nations Sustainable Development Goal, SDG 2030).

This book provides a comprehensive, state-of-the art review of HBV infection and liver disease. It discusses new data on basic and translational medicine, including the viral life cycle, the immunopathogenesis of virus-induced chronic hepatitis, viral and host genetic factors affecting disease progression, and the mechanism of virus-induced hepatocarcinogenesis, as well as their potential applications in daily clinical practice. The clinical aspects of chronic HBV infection are examined in chapters on the global epidemiology, efficacy of HBV vaccination, natural history, novel biomarkers, co-infections with HCV, HDV or HIV, and management of special populations including children, pregnant women and patients undergoing immunosuppressive therapy. Further, it describes the advances and perspectives in the development of novel antiviral treatments for possible functional cure of HBV infection.In this second edition, authors provides recent updates in epidemiology, biomarkers, antivirus therapy, and novel therapy for functional cure of chronic hepatitis B virus infection.The book is a valuable resource for medical students, physicians, and researchers who are interested in management of patients with chronic HBV infection and investigation HBV infection.

This book has included 19 recent topics about the treatment of cerebrovascular diseases from basics to surgical (include microneurosurgical, endovascular, endoscopic and Stereotactic radiosurgical techniques) aspects in the management of cerebrovascular diseases.With illustrative cases, the treatment strategies, techniques and complication avoidance have been covered extensively in the chapters to guide the readers on when and what to expect the worst in surgeries. The neurosurgical aspect in the present scenario of COVID is also included. This book will assist the junior neurosurgeons and junior neurological physicians in endeavoring to learn the core concepts and common problems of cerebrovascular surgery. This is a worthwhile addition in this ever growing field of cerebrovascular surgery.

This book is a comprehensive and timely compilation of strategy, methods, and implementation of a proof of concept modified quality module of Good Laboratory Practices (GLP). This text provides a historical overview of GLP and related standards of quality assurance practices in clinical testing laboratories as well as basic research settings. It specifically discusses the need and challenges in audit, documentation, and strategies for its implications in system-dependent productivity striving research laboratories. It also describes the importance of periodic training of study directors as well as the scholars for standardization in research processes. This book describes different documents required at various time points of a successful Ph.D and post-doc tenure along with faculty training besides entire lab establishments. Various other areas including academic social responsibility and quality assurance in the developing world, lab orientations, and communication, digitizationin data accuracy, auditability and back traceability have also been discussed. This book will be a preferred source for principal investigators, research scholars, and industrial research centers globally.From the foreword by Ratan Tata, India¿This book will be a guide for students and professionals alike in quality assurance practices related to clinical research labs. The historical research and fundamental principles make it a good tool in clinical research environments. The country has a great need for such a compilation in order to increase the application of domestic capabilities and technology¿

This comprehensive book presents the latest evidence-based data on pancreatobiliary malignancies, including the epidemiology, examination, treatment and endoscopic management. It explores a range of topics, such as risk factors, detection strategies, and novel treatment approaches like precision medicine and immunotherapy.Although there have been rapid improvements in the management of these diseases, the survival period has not yet reached a satisfactory level. This book will help those doctors needing to share the latest information with the patients and their families. It provides a wealth of practical information to help surgeons, endoscopists and oncologists as well as physicians, basic researchers and professionals at medical device and pharmaceutical companies broaden their understanding of the current treatment and management strategies for pancreatobiliary malignancies.

This book is designed to provide a crisp and necessary information for all the under-graduate and post-graduate medical students, Oral and Maxillofacial Surgeons, ENT Surgeons, General Surgeons, General Dentists and other health care workers who deal with TMDs in their practise. It includes contributions from eminent surgeons across the world who treat TMJ disorders and diseases using various conventional to modern state of the art techniques.Temporomandibular joint disorders (TMDs) are familiar yet difficult to diagnose in routine practice due to the complexity of the joint and its surrounding structures. The symptoms usually associated with TMDs present with pain, joint sounds such as click or crepitus, difficulty during mastication, reduced mouth opening are some of the many presentations. Definite diagnosis of the TMDs can be challenging as the patients present with varying symptoms. These disorders of the joint can vary from a simple disc displacement to complex pathologies. Management of the TMDs can be tricky and hence need a thorough evaluation of the joint and surrounding structures. There has been a tremendous leap in managing these disorders from simple conservative management to several advanced surgeries to salvage the joint. This compilation highlights all the relevant details regarding TMDs and its management which will offer utmost details to practising surgeons who often deal with TMDs. This book will be a delight to read for all the clinicians and surgeons who are interested in treating the small yet complex jaw joint in the facial region.

The book covers the essential practical techniques of flow cytometry in detail. It is divided into two sections: The first section includes the basic practical techniques of flow cytometry in cytology samples. Chapters under this section provide detailed description of the sampling technique, processing, acquisition of the sample, instrumentation and basic principles of flow cytometry. The second section elucidates clinical applications of flow cytometry. Chapters cover the flow cytometry applications in various haematolymphoid neoplasms, tumors of solid organs and body fluid samples. The flow cytometry findings of different tumors are described with the help of multiple colored cytology microphotographs, flow cytometry graphs, boxes, and tables. In addition, it also describes other ancillary techniques in those neoplastic lesions. The book helps practicing pathologists, technical staff and post graduate students to understand flow cytometry findings of the haematolymphoid neoplasms and solid tumor with special emphasis on cytology along with advanced technique. This book will help the students to interpret flow cytometry graphs.

This book covers interpretation of visual fields by Humphrey and Octopus perimeters and discussion of Humphrey visual fields in a variety of ocular disorders.It examines dilemmas faced by an ophthalmologist while evaluating visual fields which do not match with the clinical picture. Glaucoma, the commonest condition for visual field investigation is discussed in detail. Logical reasoningfor incorporating perimetry in glaucoma management with a clear understanding of the challenges in its interpretation is delved into. The book progresses to advanced glaucoma and glaucoma progression. It discusses a systematic evaluation of various parts of the visual field so that the reader can make a calculated management plan for their patient. Each chapter attempts to clearly enunciate factors that help in the diagnosis and features which may be confused with other conditions. Fields which help diagnosing early, advanced glaucoma and glaucoma progression with images and methods of ensuring reasonable diagnostic accuracy are included. The book incorporates separate chapters on ocular conditions which also mimic visual field defects of glaucoma with detailed modes of correct diagnosis, diagnostic dilemmas arising from retinal, macular, vascular, visual pathway lesions mimicking visual field defects of glaucoma or while coexisting with glaucoma, supported by algorithms to achieve a quick diagnosis in a busy OPD without missing the clinical findings and by using minimal investigative modalities. This book helps clinicians to prevent over diagnosis or under diagnosis of glaucoma and helps diagnose cases with morbidities causing visual field defects.

Each racial and ethnic population has their own nasal characteristics, which need to be considered when planning rhinoplasty surgery. This book is probably the first of its kind in the Indian context highlighting the goal of maintaining ethnic identity congruent with the patient¿s facial features and establishing Indian standards for gauging the success of the surgery. This is important as most of the rhinoplasty books have addressed these issues of the Caucasian or southeast Asian population and Caucasian normative standards of facial analysis. This book provides a broader understanding of ethnically specific features. It highlights the regional variations within India and their implications for rhinoplasty Surgery, thereby filling the void of lack of knowledge of the intricacies of surgery on Indian noses. It deals with important topics such as preoperative evaluations, determining factors such as thickness and texture of skin along with the various complications that may be encountered. It simplifies and facilitates learning with numerous pre-operative, intra-operative, and postoperative photographs. This book provides a systematic approach to Rhinoplasty surgery in Indian patients with an emphasis on addressing the functional aspects along with the cosmetic aspects.This book is a must-have for trainees in rhinoplasty and plastic surgery courses along with facial plastic surgeons, maxillofacial surgeons, and aesthetic surgeons operating on the Indian population across the globe.

This book offers a comprehensive overview of the latest standard medical procedures and surgical techniques for biliary atresia (BA), as well as the perioperative care, long-term follow-up and transitions. Experts on pediatrics in such fields as hepatology, surgery, pathology, and liver transplantation present their research findings and analyses of this rare and intractable disease of unknown etiology. In Japan, shared experience and sound understanding based on conferences and guidelines have led to standardization of management and clinical care and, as a result, better outcomes. Providing insights into improving surgical outcomes, and including special chapters focusing on social support systems for patients and families as well as recent advances in early diagnosis, this book a valuable resource for medical professionals around the globe who are involved in treating biliary atresia. It is especially useful for pediatric hepatologists, pediatric surgeons and transplant surgeons.

This book provides practitioners with comprehensive guidance on the application of 3D printing technology in the bone reconstruction. The 3D printed implants need to be able to maximize function and minimize complications by reinforcing strength and changing shape beyond anatomically identical design. Many of the clinical cases in this book, including pre-operative images, surgical planning, design and fabrication, 3D printing implants and guides, surgery and postoperative images, will suffice to capture the sensation of the 3D printing bone reconstruction. This book is composed of photos with minimum descriptions so that the readers can develop their imaginative view.

This Atlas covers various types of lip and nose deformities and introduces individualized surgical plan for patients. The surgical techniques are classified according to the various types of deformities. Schematic diagrams, pre-operative and post-operative photographs are supplemented by detailed explanations. It consists of four parts: anatomical structure of lips and nose; cosmetic surgery of lips and nose; plastic surgery of nasolabial congenital deformity; plastic surgery of acquired nasolabial defect and deformities.The management of nasolabial deformities and defects crosses many surgical disciplines, and therefore, this book recommended to be read by surgeons of different backgrounds i.e. oral and maxillofacial surgery, plastic surgery, cosmetic surgery, otorhinolaryngology, etc. It can also be used as a reference for anatomy, developmental biology, physiology, linguistics, aesthetics and other basic medical sciences.

The book covers all clinical aspects of pediatric cataract surgery. Chapters cover basic sciences, etiology, pre-operative evaluation, choice of intraocular lenses, steps of surgery, complications, considerations in traumatic cataract and post-operative rehabilitation. It includes photographs, diagrams, flow charts and tables for easy memorization and understanding. Multiple choice questions at the end of each chapter help to evaluate the understanding and reinforce important concepts.The book aims to encourage ophthalmic surgeons to successfully treat children with cataract as all of them perform adult cataract surgeries but usually avoid managing pediatric cases. This hesitation is primarily due to exhaustive pre-operative evaluation and long term follow up. As a result the back log of this disease in the developing world is significant and many such children are unable to receive timely intervention during their crucial period of visual development. The chapters primarily focus on the clinically relevant issues to keep the reader interested. The book includes contributions from some of the most talented and experienced pediatric cataract surgeons.The book is relevant for ophthalmologists not commonly practicing pediatric cataract surgery and post graduate students.

This book presents the epidemiology of birth defects and their public health and social implications in India. As neglected childhood disorders, birth defects remain invisible in global maternal and child health dialogues. Birth defects services are emerging in India. This book approaches birth defects from a public health perspective, identifying the core functions of a birth defects service. Keeping in mind the complex task of providing multidisciplinary services for children with disabilities and complex medical conditions, the book examines the basic public health activities that have been put in place to address these conditions in India. The book describes birth defects surveillance and the challenges of acquiring accurate and timely data on birth defects against the background of Indiäs mixed health system. It discusses opportunities for prevention of birth defects and describes the structure and function of an emergent genetic service. It explores issues related to an integrated service for children with special healthcare needs, such as screening, early intervention, and rehabilitation. Furthermore, it describes the impact of these conditions on caregivers, including birth defects stigma. This book not only addresses a knowledge gap in the field of public health in India, but also explores the broader issues of services for children with disabilities and disabling conditions in low and low-middle income settings where access to health care is not universal. Given the depth and breadth of its coverage, the book offers an essential resource for birth defects researchers, researchers in the field of maternal and child health, public health/ global health, disability researchers, and researchers from the fields of rehabilitation sciences, nursing and anthropology. This book will be a valuable read for social medicine/community medicine departments, global health courses, and public health schools in India and other low middle-income countries.

Spinal Osteotomy Orthopaedics is a monograph of introducing osteotomy for spinal deformity correction surgery. Its content is prominent and comprehensive. The unique arrangement with the combination of picture and text shows its concise, intuitive and vivid. It is a monograph for the needs of current clinical practice with quite reference value and teaching significance. The publication of Spinal Osteotomy Orthopaedics expands the scope of application of osteotomy and the combined treatment with osteotomy and internal fixation. It solved the difficult problems only by simple instruments in the past and made the spinal osteotomy further recognized by spinal surgeons in clinical application.Spinal Osteotomy Orthopaedics is composed of 13 chapters, including: History of the Development of Spinal Osteotomy, Application of Tian's Spinal Osteotomes, Transverse Laminectomy for Ankylosing Spondylitis Kyphosis, V-shape Laminectomy for Ankylosing Kyphosis, Pedicle Subtraction Osteotomy for Ankylosing Kyphosis Deformity, Vertebral Column Resection for Ankylosing Spondylitis Kyphosis, Non-apex Osteotomy for ASK, Apex Osteotomy for AS Kyphosis, Spinal Osteotomy for Congenital Angular Kyphosis, Hemivertebra Osteotomy, Osteotomy for Tuberculosis Angular Kyphosis, Posterior Vertebral Column Resection (PVCR) Correction for Severe Rigid Spinal Deformity, Osteotomy for Traumatic Spinal Deformity. They are various surgical methods of spinal osteotomy with Tian¿s Osteotomes, and also described in detail by pictures and text.The feature of this book is to illustrate the method of surgical operation to achieve the purpose of enabling beginners to quickly grasp the surgical skills. A good book is a set of handy tools dedicated to the reader. We believed that readers will benefit from it and improve the ability and application level of spinal osteotomy and surgery.

This book is a comprehensive and up-to-date guide to intraoperative neurophysiological monitoring in patients with hemifacial spasm, one of the very few neuromuscular disorders that can be treated surgically.It covers various aspects including brainstem auditory evoked potentials, lateral spread response, free-running EMG and prognosis, and intraoperative hearing loss patterns. In particular, we present detailed explanations and realistic pictures of various and subtle changes in the waveform of brainstem auditory evoked potentials and postoperative hearing.In addition, detailed explanations and actual photos are provided for various cases, such as when the amplitude of the lateral spread response is slightly smaller during surgery, when it is lost and then measured again, or when the surgery is terminated without disappearing. The various situations that may occur during surgery are fully covered, and the causes of and solutions to particular challenges are clearly described. In addition, the results of each test and their association with the postoperative prognosis are explained in detail. The authors have vast experience and recognized expertise in the performance of microvascular decompression surgery and intraoperative neuromonitoring. The book draws on their practical knowledge and many scientific contributions to offer the very latest insights into the management of hemifacial spasm. It will be an excellent guide for young neurosurgeons, neurological monitoring technologists, and neurological interpreters.

This book includes major issues in wound tissue repair and regeneration in 14 chapters. The topics start from cytological basis, molecular and genetic basis, skin development, to the tissue repair, visceral injury and tissue engineering. In the second part, it introduces Chinese researchers¿ contribution in wound repair and regeneration. Specially, it has 3 chapters discussing new technologies in tissue repair and regeneration, and 1 chapter in Traditional Chinese Medicine.