Bücher veröffentlicht von Springer Verlag, Singapore

The book discusses all aspects of choroidal neovascularization (CNV), including the basics, clinical conditions associated with CNV, clinical trials related to CNV, future directions and rehabilitation. The first section covers the pathogenesis, proposed mechanisms, disease models, histopathology and electronmicroscopy. The next section explores CNV secondary to various clinical conditions, such as age-related macular degeneration (AMD), myopia, and less common conditions like choroidal osteoma. The book also covers clinical features, imaging characteristics, and treatment approaches, as well as clinical trials in CNV conditions with recent updates. Lastly, it features chapters on stem cell therapy, gene therapy, new molecules, and lasers, as well as a section on rehabilitation, which addresses home monitoring and low vision aids.This book is intended for retina specialists, retina fellows and general ophthalmologists.

This book outlines the electro-activity in the human body, human behavior, and other bio-information during image viewing and applies it to a hygienic and clinical setting. The book begins by explaining the basic science of brain measurements and the endocrine system, before analyzing the bio-signals obtained from electrocardiogram (ECG), electrogastrography (EGG), electro-oculography (EOG) and much more. As the book subsequently demonstrates, these bio-signals can be measured using wearable devices, and the data can be used to detect undiagnosed diseases and health-relevant abnormalities. Especially in the field of nursing care for the elderly and rehabilitation, these new options for the management and analysis of biological information hold considerable potential. Bio-information for Hygiene offers a valuable resource for both new and established researchers, as well as students who are seeking comprehensive information on environmental/occupational health and healthpromotion. It will also assist technical staff whose work involves bio-informatics.

This book addresses surgical management for recurrent soft tissue sarcomas (RSTS) based on a wealth of clinical cases. With aim to reduce recurrence rate, a surgical strategy of barrier resection plus repair reconstruction referring to natural barriers in human body for enhancing curative effect is presented in details. The first part introduces the general theory of surgical treatment for RSTS. The second part is a portfolio of clinical cases, showing the essential of the surgical strategy from hundreds of cases with tumour of different anatomical sites. Each case report is composed of detailed medical history, radiographic images and operational photos. It will help readers to make proper decisions on the basis of specific purposes. This book will be of benefit to oncologists, orthopaedic surgeons, general surgeon, plastic surgeons, and medical students.

This book presents up-to-date information on the clinical-pathophysiological features of acute renal injury and discusses the KDIGO diagnostic criteria, as well as novel experimental findings, including in the area of regenerative medicine. It also highlights the clinical-pathophysiological importance of AKI in clinical settings, including differential diagnoses and management of AKI. In the past, the pathology associated with sudden renal impairment was characterized as acute renal failure (ARF). However, in the 2000s, the joint efforts of specialists in fields including nephrology, intensive care medicine, and cardiovascular medicine led to the introduction of a novel concept known as acute kidney injury (AKI). As medical care progressed, patients such as high-risk elderly subjects who were not deemed to be candidates for invasive therapy came to be treated in intensive care units (ICUs). As a result, kidney injury as a subset of multiple organ failure was re-considered as AKI, especially in intensive care medicine. AKI was then proposed as a novel disease concept to emphasize the importance of early diagnosis and early intervention to improve prognosis.Presenting novel features, such as the definition of AKI, risk factors and management; biomarkers, such as neutrophil gelatinase-associated lipocalin (NGAL) and L-type fatty acid-binding protein (L-FABP); long-term outcomes of AKI; as well as renal regeneration using iPS cell, manipulation of embryonic genes, and Xenotransplanted embryonic kidney, this book is of interest to all physicians and researchers in this field around the globe.

This book demonstrates the recent advances in rapid on-site evaluation (ROSE) for differential diagnosis of interstitial lung disease (ILD). Interstitial lung disease is a group of diffuse parenchymal lung disorders affecting the interstitium, a part of the lung's anatomic structure, causing inflammation, scarring, or excess fluid. ILDs include interstitial pneumonia, idiopathic pulmonary fibrosis, nonspecific interstitial pneumonitis, cryptogenic organizing pneumonia and sarcoidosis, which are associated with various degrees of morbidity and mortality rates. ROSE has proven its value in diagnosis with routine transbronchial lung biopsy (TBLB) procedures, especially in difficult clinical cases. The first part of the book discusses the principals of performing ROSE procedures, reviews the basic concepts and summarizes the distribution and morphology of tracheal/ bronchial/ pulmonary cells. The second part covers specific interstitial disorders, including a number of difficult and rare cases, and features iCT images and cytological illustrations. Providing readers with valuable insights, the book is an important resource for practitioners involved in the care and treatment of patients with ILD. This book is part of the 4-volume collection ROSE in Diagnostic Interventional Pulmonology.

The second edition of this highly successful book includes up-to-date notes on the step-wise management of clinical emergencies encountered in everyday intensive care units (ICU). Each thoroughly revised chapter provides concise information for point-of-care treatment, making it a practical guide clinicians can refer to on a daily basis at work or while traveling, or just to expand their knowledge. Volume 2 of ICU Protocols covers topics in the endocrine and metobolic systems, oncology, trauma, toxicology, envenomation and thermodysregulation, obstetrics, perioperative care, pediatrics and ICU procedures. Pulmonology, cardiology, neurology, gastroenterology, nephrology and infectious diseases are covered in the first volume of ICU Protocols. This two-volume book is a must-read for intensivists, critical care specialists, junior trainees and residents working in ICUs. It is also relevant as course material for workshops on critical care, and essential for allhospital-based libraries. ¿This book provides junior trainees with an introduction to the management of problems common to the critical care unit.¿ David J Dries, Doody¿s Book Reviews, March, 2013, for the first edition of ICU Protocols.

This book provides concise and cutting-edge studies on threats resulting from exposure to environmental chemicals that can affect human health and development, with a particular emphasis on the DOHaD concept. The book is divided into five main parts, the first of which includes an introduction to the impacts of developmental exposure to environmental chemicals and historical perspectives, while the second focuses on how environmental chemicals can affect human organs, including neurodevelopment, immune functions, etc. In turn, the third part addresses the characteristics of specific chemicals and their effects on human health and development, while the fourth part provides a basis for future studies by highlighting the latest innovations in toxicology, remaining challenges, and promising strategies in children¿s environmental health research, as well as ideas on how to bridge the gap between research evidence and practical policymaking. The fifth and last part outlines furtherresearch directions and related policymaking aspects.Health Impacts of Developmental Exposure to Environmental Chemicals will appeal to young and veteran researchers, students, and physicians (especially gynecologists and pediatricians) who are seeking comprehensive information on how children¿s health can be affected by harmful chemicals and other environmental toxicants.

This volume of the retina atlas focuses on hereditary chorioretinal disorders. The topics covered include retinitis pigmentosa, Best disease, congenital X-linked retinoschisis, cone dystrophy, Stargardt¿s disease, pattern dystrophy, North Carolina macular dystrophy, choroideremia, Mallattia Leventinese, Bietti¿s crystalline dystrophy, and albinism. All clinical features are clearly illustrated with multimodal imaging techniques. The utility of some of the latest imaging tools such as OCT angiography, adaptive optics-scanning laser ophthalmoscopy, and microperimetery is discussed. Readers will gain valuable new insights into pathogenesis at the molecular level, which have been facilitated by recent genetic discoveries. The use of genetic testing and the latest advances in and challenges of gene therapy and cell-based therapy are also covered in detail.Hereditary Chorioretinal Disorders atlas is one of nine volumes in the series Retina Atlas.The series provides validated and comprehensive information on vitreoretinal diseases, covering imaging basics, retinal vascular diseases, macular disorders, ocular inflammatory and infectious disorders, retinal degeneration, the surgical retina, ocular oncology, pediatric retina and trauma.

This book addresses the most relevant aspects of radiation oncology in terms of technical integrity, dose parameters, machine and software specifications, as well as regulatory requirements. Radiation oncology is a unique field that combines physics and biology. As a result, it has not only a clinical aspect, but also a physics aspect and biology aspect, all three of which are inter-related and critical to optimal radiation treatment planning.In addition, radiation oncology involves a host of machines/software. One needs to have a firm command of these machines and their specifications to deliver comprehensive treatment. However, this information is not readily available, which poses serious challenges for students learning the planning aspect of radiation therapy. In response, this book compiles these relevant aspects in a single source.Radiation oncology is a dynamic field, and is continuously evolving. However, tracking down the latest findings is both difficultand time-consuming. Consequently, the book also comprehensively covers the most important trials. Offering an essential ready reference work, it represents a value asset for all radiation oncology practitioners, trainees and students.

This book addresses the most relevant aspects of radiation oncology in terms of technical integrity, dose parameters, machine and software specifications, as well as regulatory requirements. Radiation oncology is a unique field that combines physics and biology. As a result, it has not only a clinical aspect, but also a physics aspect and biology aspect, all three of which are inter-related and critical to optimal radiation treatment planning.In addition, radiation oncology involves a host of machines/software. One needs to have a firm command of these machines and their specifications to deliver comprehensive treatment. However, this information is not readily available, which poses serious challenges for students learning the planning aspect of radiation therapy. In response, this book compiles these relevant aspects in a single source.Radiation oncology is a dynamic field, and is continuously evolving. However, tracking down the latest findings is both difficult and time-consuming. Consequently, the book also comprehensively covers the most important trials. Offering an essential ready reference work, it represents a value asset for all radiation oncology practitioners, trainees and students.

This book introduces the clinical analysis and accompany cases of paediatric Kawasaki disease. It has 14 chapters about typical Kawasaki disease, atypical Kawasaki disease, recurrent, misdiagnosis, and complications involved different systems, such as cardiovascular, digestive, nervous, blood, respiratory, urinary, bone and joints, and endocrine systems complications. In this book, 53 Kawasaki cases are presented with clinical history, physical examination, laboratory findings, diagnosis, treatment and discussion.This book is helpful for clinicians, ultrasonologist, and radiologist to support early diagnosis and proper treatment, which can significantly improve the prognosis of Kawasaki disease.