Bücher veröffentlicht von Springer Verlag, Singapore

This book provides an evidence-based approach to the diagnosis and surgical management of the diseases of the pancreas and biliary tree, highlighting the most recent findings. The chapters are designed to accompany the reader on a step-by-step approach to the patient, providing the latest evidence to justify each recommendation. Wherever feasible and indicated, emphasis is placed on the use of tables and algorithms to simplify decision-making.The information contained in this well-referenced book is thus relevant not only to practicing pancreatobiliary and general surgeons, but also offers valuable guidance for surgical trainees. This book covers 14 diseases of the pancreas and biliary tree, from the more common gallstones and common bile duct stones, acute and chronic pancreatitis, to more complex benign conditions such as biliary fistulae and strictures, as well as cystic tumors of the pancreas, and finally the major malignancies include gallbladder cancer, pancreatic cancer and hilar cholangiocarcinoma.

This book provides a systematic description of fundamental knowledge, application methods, and management issues about the clinical application of endovascular surgery and device. It is organized as the three parts. Part 1 introduces the development background of endovascular device and its knowledge hierarchy, and gives an overview on classification, structure, shape, and characteristics of the above device. Part 2 is based on a large number of clinical practices. It firstly summarizes the basic operation skills and conventional methods of endovascular device, and then exemplifies the application scheme of special device for complex cases. Part 3 discusses the management theory and methods of endovascular device in clinical application, puts forward the agile supply chain management model and autonomous intelligent decision-making method of device supply and cooperation management for clinical surgery, and designs its managerial system and guides.This book provides comprehensive and professional knowledge, advanced theory, and referential methods for clinical application and management of endovascular surgery and device. It is a useful guide for the clinical practice in specialized study and professional training in endovascular surgery, and provides the methods of neuro-management and smart medical service for patients.

This book describes the underlying genetic basis of common pulmonary diseases and discusses their pathogenesis and pathophysiology. These insights provide the basis for understanding different subtypes and phonotypes, and will promote better treatment strategies and individualized medicine. The book provides new and valuable information for the development of the areas of study, as well as practical guidelines for clinicians engaged in treating pulmonary diseases.This volume of the Respiratory Disease Series - Diagnostic Tools and Disease Managements will broaden the understanding of beginning and experienced researchers and clinicians who treat pulmonary diseases. Moreover, residents and clinicians engaged in medical oncology will find it a valuable guide to support them in their day-to-day work.

Focusing on the practical use of N-Acetyl-Cysteine (NAC) in medicine, this book provides a comprehensive review of the basic biological and clinical studies documenting its benefits in treating medical disease. NAC is perhaps best known as an antidote for acetaminophen, but its therapeutic effect in a wide range of medical diseases has recently been realized. In addition to its well recognized use in radiological contrast prophylaxis for renal disease and pulmonary disorders, studies have suggested significant promise in psychiatric and neurological disorders such as addiction, Alzheimer's disease, ataxia, autism, bipolar disorder, depression, epilepsy, neuropathy, obsessive-compulsive disorder, schizophrenia, traumatic brain injury and trichotillomania in addition to promising studies in audiology, cardiology, exercise physiology, gastroenterology, hematology, infectious disease, infertility and ophthalmology. Given the promising studies for a wide range of medical conditions, coupled with a excellent safety profile, the potential for NAC in the treatment of human disease appears considerable.Dr Leonore A Herzenberg from Stanford University, a pioneer of redox physiology and the use of NAC, provides a succinct history of the development of the therapeutic use of NAC for medical disease. This is followed by a series of basic science chapters outlining the role of NAC in important physiological processes, including modulation of dopamine and glutamate neurotransmitter systems, redox and mitochondrial metabolism, apoptosis and inflammation.The last section of the book is dedicated to clinically oriented chapters that comprehensively review the literature on medical disorders in which NAC has been found to be effective, including toxicity and cardiovascular, gastrointestinal, neurological, psychiatric, pulmonary and renal disorders. Each chapter reviews the theoretical biological mechanisms of NAC for the specific diseases reviewed, rates the clinical studies using a standardized criteria in order to provide an objective level of evidence and grade of recommendation for the use of NAC for specific medical conditions and outlines the ongoing clinical trials examining NAC for the treatment of specific diseases. Final chapters review the clinical evidence verifying that specific theoretical biological mechanisms are actually being targeted by NAC in medical disease. Studies on the pharmacology, formulation and potential adverse effects of NAC are also reviewed. A final chapter synthesizes the clinical studies to suggest that the effectiveness of NAC may signal a new basic physiological disorder, glutathione deficiency, which may be an important pathophysiological mechanism of many diseases.

The second edition of this very popular atlas is designed to serve as an up-to-date guide to the diagnostic use of gastrointestinal endoscopy that will meet the daily needs of both novice and advanced endoscopists. The atlas presents an abundance of typical and atypical endoscopic images of common and rare diseases of the esophagus, stomach, small intestine, and colorectum, accompanied by precise clinical descriptions. Normal findings and variants are also amply documented. A large majority of the illustrations in the new edition are superb high-resolution images, reflecting the important advances of recent years. The coverage also includes the role of novel endoscopic technologies such as narrow band imaging, FICE, iScan, and confocal laser endomicroscopy. A further new feature is the inclusion of an interesting quiz at the end of each chapter in order to summarize complex knowledge, enhance understanding, and assist in the internalization of important practical tips. Clinical Gastrointestinal Endoscopy: A Comprehensive Atlas is expected to become the ultimate reference for gastrointestinal endoscopists worldwide.

This book aims to raise awareness of IgG4-related sclerosing cholangitis among practicing physicians and to equip readers with a sound understanding of the principles of diagnosis and treatment. Clinical, serological, and histopathological features are clearly described and imaging appearances on all relevant modalities are illustrated, covering the bile duct and other involved organs. Differential diagnosis from other diseases, including primary sclerosing cholangitis and cholangiocarcinoma, is precisely explained. Information is then presented on all significant current and emerging therapeutic strategies, including steroids, immunosuppressive drugs, and rituximab. Finally, attention is drawn to significant prognostic features. While IgG4-related sclerosing cholangitis is now a widely acknowledged condition, most practitioners are still liable to misdiagnose it owing to a lack of familiarity with its presenting features. This book should help to rectify the situation and will be an asset for all who may encounter the disease in clinical practice.

This book represents an ambitious effort to bring leading Yijing scholars together to examine the globalisation and localisation of the 'Book of Changes' from cross-cultural and comparative perspectives. It focuses on how the Yijing has been used to support ideologies, converted into knowledge, and assimilated into global cultures in the modern period, transported from the Sinosphere to British, American and French cultural traditions, travelling from East Asia to Europe and the United States. The book provides conceptualised narratives and cross-cultural analyses of the global popularisation and local assimilation of the Yijing, highlighting the transformation and application of the Yijing in different cultural traditions, and demonstrating how it acquired different meanings and took on different roles in the context of a global setting. In presenting a novel contribution to understandings of the multifaceted nature of the Yijing, this book is essential reading for scholarsand students interested in the 'Classic of Changes'. It is also a useful reference for those studying Chinese culture, Asian philosophy, East Asian studies, and translation studies.

This monograph compares two trade agreements among three important economic regions, namely, the KoreäEU free trade agree (FTA) and the Japan¿EU Economic Partnership Agreement (EPA). The two new types of agreements came into effect in the 2010s. They not only create more favorable trade and economic conditions in these regions but also produce spillover effects to bring about more comprehensive conditions in other area. First, the quantitative research for both agreements using the CGE model and a tentative analysis of the Japan¿EU EPA in the analysis show that both have already created positive impacts on all three economies by lifting or reducing tariff and non-tariff barriers. Such positive impacts are also expected to be felt by SMEs in these countries that are involved. Additionally, the high level of tariff and non-tariff liberalization in the two current agreements will make positive impacts on the negotiation of other FTAs and on WTO reform. The advantages of the FTAand EPA dealt with in this book are not restricted to these economic effects. As the agreements are comprehensive, they will create more favorable social conditions not only in these economic regions but in other areas of Asia as well.

This collection of interviews explores how the Chinese Dream is fueling the aspirations of individuals in China today and presents 40 representative cases that showcase the journeys that ordinary people undertake in pursuit of their dreams as well as their extraordinary achievements. The authors identify autonomy, self-awareness, and hard work as the most fundamental driving forces in individuals taking control of their own lives and achieving their dreams, with family and social support as further important factors. Despite the vast differences in the interviewees¿ dreams and experiences in pursuing them, there is a common thread in their stories, namely the impact of major changes in the country on their lives. The future of individuals is closely linked to the future of the country: a bright future for the country means a good life for all. People¿s longing for a better life is the basis and a central element of the Chinese Dream, which isthe dream of the nation and the dream of every citizen. This book will appeal to a wide audience, including ordinary people.

This book is a collection of research papers selected for presentation at the International Conference on Smart Computational Methods in Continuum Mechanics 2021, organized by Moscow Institute of Physics and Technology and the Institute for Computer Aided Design of Russian Academy of Sciences. The work is presented in two volumes. The primary objective of the book is to report the state-of-the-art on smart computational paradigms in continuum mechanics and explore the use of artificial intelligence paradigms such as neural nets, and machine learning for improving the performance of the designed engineering systems. The book includes up-to-date smart computational methods which are used to solve problems in continuum mechanics, engineering, seismic prospecting, non-destructive testing, and so on. The main features of the book are the research papers on the application of novel smart methods including neural nets and machine learning, computational algorithms, smart software systems, andhigh-performance computer systems for solving complex engineering problems. The case studies pertaining to the real-world applications in the above fields are included. The book presents a collection of best research papers in English language from some of the world leaders in the field of smart system modelling and design of engineering systems.