Bücher veröffentlicht von World Scientific Europe Ltd

From the lens of holistic systems theory, this book discusses strategic management adapted to evolving convergence in an era of advanced ICT from the viewpoint of the major management elements of strategy, organizations, technologies, operations and leadership.To discuss corporate change in response to such advanced technology in a theoretical and empirical manner, it is necessary not only to analyze and consider individual management elements such as strategy, organizations, technologies, operations and leadership in a piece-meal manner but also to determine the research issues from a framework based on a holistic management perspective through systems theory including interaction between and among the respective individual management elements (from micro to macro elements).Applying both innovation theory and capabilities theory, this book presents a new framework and knowledge for holistic strategic management from a systems theory lens that focuses on the issue of how major corporations can develop capabilities to achieve strategic innovation in response to the impacts of advanced ICT on corporate management.

Indole derivatives are the most common heterocycle compounds present in nature, for this reason, they have been referred to as "privileged structures". In fact, many approved drugs - and natural products - belong to this family. Among indole derivatives, oxindoles have a structural complexity, which have stimulated generations of synthetic chemists to design strategies for assembling these structures, and their enantioselective synthesis is still growing.This book proposes to describe the known enantioselective syntheses of oxindole derivatives. It is divided in six chapters each referring to a specific class of asymmetric oxindole derivatives. After the introduction, Chapter 2 describes all-carbon spirooxindoles; Chapter 3, open chain 3,3-dialkyloxindoles; Chapter 4, 3-substituted-3-aminooxindoles; Chapter 5, 3-substituted-3-hydroxyoxindoles; Chapter 6, 3-hetero-3-substituted oxindoles. It will be a useful tool for synthetic chemists, who assemble total synthesis of natural products, as well as for drug discovery chemists either in academic or in industry R&S laboratories.

Rethinking Evolution links Darwin's early insights to the molecular realm inside living cells. This updated evolutionary synthesis provides an accessible explanation for biological complexity that cuts through the confusion surrounding evolutionary theory in a practical way.In addition to a wide-ranging survey of proposed updates to the modern synthesis, this title provides extraordinary new insights including emergent evolutionary potential and the generative phenotype. Drawing on well-characterized empirical facts, Rethinking Evolution transcends classical Darwinian natural selection while retaining those core principles that have stood the test of time.The updated synthesis brings a broad spectrum of specialized research together to provide a more plausible naturalistic explanation for biological evolution than ever before. Perspectives ranging from the role of energy in the origin of life to the networks of protein-DNA interactions that govern multicellular development are woven together in a robust conceptual fabric consistent with 21st century cutting-edge research.Inspired in part by the surprising ways that DNA sequences change - such as his early discovery of a fundamental mispairing mechanism by which DNA sequences expand - and drawing on a career's worth of experience both as a research scientist as well as a biology and chemistry tutor - the author provides an engaging account that is essential reading - both for the public awareness and understanding of the science of evolution and for students and professionals in the biomedical sciences.

This title introduces the theory of arc schemes in algebraic geometry and singularity theory, with special emphasis on recent developments around the Nash problem for surfaces. The main challenges are to understand the global and local structure of arc schemes, and how they relate to the nature of the singularities on the variety. Since the arc scheme is an infinite dimensional object, new tools need to be developed to give a precise meaning to the notion of a singular point of the arc scheme.Other related topics are also explored, including motivic integration and dual intersection complexes of resolutions of singularities. Written by leading international experts, it offers a broad overview of different applications of arc schemes in algebraic geometry, singularity theory and representation theory.

This work presents a comprehensive theory describing atomic diffusion in silicon crystals under strong nonequilibrium conditions caused by ion implantation and interaction with the surface or other interfaces. A set of generalized equations that describe diffusion of impurity atoms and point defects are presented in a form suitable for solving numerically. Based on this theory, partial diffusion models are constructed, and the simulation of many doping processes used in microelectronics is carried out.Coupled Diffusion of Impurity Atoms and Point Defects in Silicon Crystals is a useful text for researchers, engineers, and advanced students in semiconductor physics, microelectronics, and nanoelectronics. It helps readers acquire a deep understanding of the physics of diffusion and demonstrates the practical application of the theoretical ideas formulated to find cheaper solutions in the course of manufacturing semiconductor devices and integrated microcircuits.

A unique title comparing rural policies and employment in the two most developed parts of the world — the EU and USA. While both regions are concerned for their vast rural areas, each adopts a strikingly different approach to create and maintain employment there, making rural space attractive to businesses and residents.This book focuses on a major issue of socioeconomic and policy concern, i.e. whether jobs and incomes can be protected or created in rural areas, where often agriculture no longer provides a large and secure basis for employment. Within a "paired" chapter structure covering both the European Union and the United States of America, it deals with several themes of interest including farm policies, labor entry and exit, and rural and household enterprise diversification. Specific "special studies" also analyze recent developments within countries or regions.

This unique advanced textbook provides a clear and comprehensive overview of gene delivery, gene therapy and genetic pharmacology, with descriptions of the main gene transfer vectors and a set of selected therapeutic applications, along with safety considerations. The second edition features new groundbreaking material on genome editing using the recently discovered CRISPR/Cas9 system and on cancer immunotherapy by CAR-T cells. It also presents the historical milestone of gene therapy application in the field of severe combined immunodeficiency, and other fields of gene therapy and molecular medicine.The use of gene transfer is exponentially growing in the scientific and medical communities for day-to-day cell biology experiments and swift development of gene therapy, which is already revolutionizing medicine. In this advanced textbook, more than 30 leading scientists come together to explore these topics.This educational introduction provides the background material needed to further explore the subject as well as relevant research literature. It is an invaluable resource to Master, PhD or MD students, post-doctoral scientists or medical doctors, as well as any scientist wishing to deliver a gene or synthetic nucleotide or develop a gene therapy strategy. The second edition's simple and synthetic content will be of value to any reader interested in the biological and medical revolution derived from the elucidation of the human genome.

This unique advanced textbook provides a clear and comprehensive overview of gene delivery, gene therapy and genetic pharmacology, with descriptions of the main gene transfer vectors and a set of selected therapeutic applications, along with safety considerations. The second edition features new groundbreaking material on genome editing using the recently discovered CRISPR/Cas9 system and on cancer immunotherapy by CAR-T cells. It also presents the historical milestone of gene therapy application in the field of severe combined immunodeficiency, and other fields of gene therapy and molecular medicine.The use of gene transfer is exponentially growing in the scientific and medical communities for day-to-day cell biology experiments and swift development of gene therapy, which is already revolutionizing medicine. In this advanced textbook, more than 30 leading scientists come together to explore these topics.This educational introduction provides the background material needed to further explore the subject as well as relevant research literature. It is an invaluable resource to Master, PhD or MD students, post-doctoral scientists or medical doctors, as well as any scientist wishing to deliver a gene or synthetic nucleotide or develop a gene therapy strategy. The second edition's simple and synthetic content will be of value to any reader interested in the biological and medical revolution derived from the elucidation of the human genome.

Managing Innovation is a three-part series covering contemporary technology and innovation management research areas. Each volume comprises key articles from both the International Journal of Innovation Management and the International Journal of Innovation and Technology Management, published by World Scientific, and provides an international, disciplinary approach across its broad coverage of topics.Relevant for both academics and practitioners, this volume focuses on key aspects of crowd innovation including motivations, challenges and benefits of this approach.

Managing Innovation is a three-part series covering contemporary technology and innovation management research areas. Each volume comprises key articles from both the International Journal of Innovation Management and the International Journal of Innovation and Technology Management, published by World Scientific, and provides an international, disciplinary approach across its broad coverage of topics.Relevant for both academics and practitioners, this volume answers how organisations can develop innovative approaches from a perspective that encompasses technological advances, changes in the market and individual entrepreneurs.

Managing Innovation is a three-part series covering contemporary technology and innovation management research areas. Each volume comprises key articles from both the International Journal of Innovation Management and the International Journal of Innovation and Technology Management, published by World Scientific, and provides an international, disciplinary approach across its broad coverage of topics.Relevant for both academics and practitioners, this volume looks at the international aspects of innovation with case studies from China, Germany, India and Russia.

Geometric function theory is one of the most interesting parts of complex analysis, an area that has become increasingly relevant as a key feature in the theory of Schramm-Loewner evolution.Though Riemann mapping theorem is frequently explored, there are few texts that discuss general theory of univalent maps, conformal invariants, and Loewner evolution. This textbook provides an accessible foundation of the theory of conformal maps and their connections with geometry.It offers a unique view of the field, as it is one of the first to discuss general theory of univalent maps at a graduate level, while introducing more complex theories of conformal invariants and extremal lengths. Conformal Maps and Geometry is an ideal resource for graduate courses in Complex Analysis or as an analytic prerequisite to study the theory of Schramm-Loewner evolution.

This practical introduction explains the field of Blockchain Economics, the economic models emerging with the implementation of distributed ledger technology. These models are characterized by three factors: open platform business models, cryptotoken money supplies, and Initial Coin Offerings as a new and official form of financing. The book covers a variety of approaches from a business and academic perspective, ranging from financial theory, complexity, and open innovation networks to behavioral economics, self-determination theory, public policy, and financial inclusion.Unlike existing titles, this book draws on worldwide blockchain industry experts to define the new discipline of Blockchain Economics and provide novel theoretical and conceptual resources for the future of this fast-developing economy. The primer also highlights the wider theme of blockchain as an institutional technology, in that many value transfer interactions might be shifted to automated networks, decreasing the number of human-operated institutions.As well as stimulating further research, and implementation by business innovators and public policy strategists, the book can also be used as a foundational textbook in courses on Blockchain Economics.

The book focuses on how leaders are learning to develop the creative capabilities of their team members and themselves. Through this learning, teams are developing original approaches to their work, benefitting their customers, patients, employees and other stakeholders.Using a strong interdisciplinary approach, How Leaders Learn to Boost Creativity in Teams introduces insights from the domains of psychology, creativity, leadership and power, and integrates these through a proposed framework for leading innovation. It contains nine in-depth, current-day cases of learning and workplace-based applications and has an optimistic message: creativity can be learnt. Making connections between current day research, learning and application in work contexts, it will appeal to leaders and students alike seeking to think outside of the box.

The use of organocatalysts able to photocatalyze an organic reaction is a rapidly growing field. These photocatalyzed transformations are more environmentally sustainable with respect to the use of expensive/toxic metal-based (photo)catalysts.Based on the authors' extensive experience in photogenerated intermediates, this book presents an overview on photocatalyzed organic processes having a synthetic significance, where an organic molecule functions as the photocatalyst.

As one of the typical intermolecular interactions, hydrogen-bonding plays a significant role in molecular structure and function. When the hydrogen bond research system is connected with the photon, the hydrogen-bonding effect turns to an excited-state one influencing photochemistry, photobiology, and photophysics. Thus, the hydrogen bond in an excited state is a key topic for understanding the excited-state properties, especially for optoelectronic or luminescent materials.The approaches presented in this book include quantum chemical calculation, molecular dynamics simulation and ultrafast spectroscopy, which are strong tools to investigate the hydrogen bond. Unlike other existing titles, this book combines theoretical calculations and experiments to explore the nature of excited-state hydrogen bonds. By using these methods, more details and faster processes involved in excited-state dynamics of hydrogen bond are explored.This highly interdisciplinary book provides an overview of leading hydrogen bond research. It is essential reading for faculties and students in researching photochemistry, photobiology and photophysics, as well as novel optoelectronic materials, fluorescence probes and photocatalysts. It will also guide research beginners to getting a quick start within this field.

The book addresses surrogate-assisted design of antenna arrays, in particular, how surrogate models, both data-driven and physics-based, can be utilized to expedite procedures such as parametric optimization, design closure, statistical analysis, or fault detection. Algorithms and design frameworks are illustrated using a large variety of examples including real-world printed-circuit antenna and antenna array structures.This unique compendium contains introductory materials concerning numerical optimization, both conventional (gradient-based and derivative-free, including metaheuristics) and surrogate-based, as well as a considerable selection of customized procedures developed specifically to handle antenna array problems. Recommendations concerning practical aspects of surrogate-assisted multi-objective antenna optimization are also given. The methods presented allow for cost-efficient handling of antenna array design problems (involving CPU-intensive EM models) in the context of design optimization and statistical analysis, which will benefit both researchers, designers and graduate students.

This volume contains an accessible, yet critical, discussion of the most complementary-alternative treatments based on medical evidence.Providing readers at any level an introduction to alternative and supplementary medicines, the book is a simplified, complete text including management and medical information. It is arranged in a direct manual style, with select information explaining some of the most important concepts of complementary and alternative medicine and circulation sciences.

Unlike the election models in other Asian countries, rural elections in China had been created from the grassroots level by farmers before they were officially and legally recognized by the government.As China is going through rapid urbanization and an increasing number of rural population is moving to cities, village elections and power structures in the villages are also experiencing changes. By drawing on over 2,000 rural elections cases in China, this book analyzes the latest developments and decipher their implications ΓÇö not only for village elections, but also for China''s democratization process. It also tries to examine the interplay between state power and village elections: whether one grows at the expense of the other. Readers interested in China''s rural elections will find the book a useful read.

Designed for those who wish to understand and engage with the principles behind the process of crystal structure determination by X-ray diffraction, this title contains a comprehensive series of chapters, each of which concludes with a set of problems, for which solutions are provided. An ideal resource for senior undergraduates and early-stage postgraduates, The Essence of Crystallography has an accompanying website with programs written for the text, including an interactive simulation of crystal structure determination using prepared intensity data sets.The Program Suite comprises programs designed around the text in order to assist in both understanding the textual material and solving problems related to it.

In this volume, international leading experts in the study of thermally and optically luminescence give an up-to-date, comprehensive coverage of the theoretical and experimental aspects of these subjects, as well as their applications.The theory of thermoluminescence (TL) and optically stimulated luminescence (OSL) are discussed in detail including mainly solid state models of localized and delocalized transitions. These models cover the effects occurring during the excitation by irradiation and the read-out by heating or by exposure to light. The methods described consist of analytical mathematical considerations as well as numerical simulations.The main application of these effects, namely radiation dosimetry, includes personal and environmental dosimetry, as well as retrospective dosimetry and the dosimetry of cosmic radiation and space missions. Also discussed in detail are archaeological and geological dating, the use of luminescence dosimetry in medical physics as well as general applications in geosciences, other model subjects such as time-resolved luminescence and thermally assisted OSL, and the sister-subject of thermoluminescence in photosynthetic materials.

The methodology of analytical pyrolysis-GC/MS has been known for several years, but is seldom used in research laboratories and process control in the chemical industry. This is due to the relative difficulty of interpreting the identified pyrolysis products as well as the variety of them. This book contains full identification of several classes of polymers/copolymers and biopolymers that can be very helpful to the user. In addition, the practical applications can encourage analytical chemists and engineers to use the techniques explored in this volume.The structure and the functions of various types of pyrolyzers and the results of the pyrolysis–gas chromatographic–mass spectrometric identification of synthetic polymers/copolymers and biopolymers at 700°C are described. Practical applications of these techniques are also included, detailing the analysis of microplastics, failure analysis in the automotive industry and solutions for technological problems.

Cyber-security is a matter of rapidly growing importance in industry and government. This book provides insight into a range of data science techniques for addressing these pressing concerns.The application of statistical and broader data science techniques provides an exciting growth area in the design of cyber defences. Networks of connected devices, such as enterprise computer networks or the wider so-called Internet of Things, are all vulnerable to misuse and attack, and data science methods offer the promise to detect such behaviours from the vast collections of cyber traffic data sources that can be obtained. In many cases, this is achieved through anomaly detection of unusual behaviour against understood statistical models of normality.This volume presents contributed papers from an international conference of the same name held at Imperial College. Experts from the field have provided their latest discoveries and review state of the art technologies.