Bücher veröffentlicht von World Scientific Europe Ltd

This book is a 360⁰ view of vascular pathologies and an introduction to the complexity of the most important field in medicine, with topics including cardiovascular disease, atherosclerosis, venous diseases, investigations, population sciences, prevention and the indication of a specialization field.It offers a broad introduction to angiology and vascular diseases, surgery and medicine, in an easy-to-read format with case studies separated under key areas. The scope includes many different aspects at an introductory level under a single observational point, bringing unity and homogeneity in the otherwise disjointed field of circulation sciences.

This book constitutes a concise introductory course on Functional Analysis for students who have studied calculus and linear algebra. The topics covered are Banach spaces, continuous linear transformations, Frechet derivative, geometry of Hilbert spaces,

This book spans concepts from multiple disciplines in the social sciences, making it relevant not only to undergraduate and graduate students in futures studies, environmental studies, economics, and business, but also national policymakers, think tanks, corporate operators and indeed for any one seriously interested in the future.

This book is designed to be an easy-to-use guide to understanding the ethical and biosecurity implications of life science research.

Processes involving randomly moving particles, which react either upon encounter or via distance-dependent reaction rates, are ubiquitous in nature. A few stray examples are recombination of ions or holes and electrons, excitation energy migration and quenching, trapping of particles by other species, coagulation, binding of ligands and proteins to specific sites, chemotaxis, catalytically-induced self-propulsion, polymerization, growth of dendrites or aggregates, or nuclei of a new phase.Several decades ago, it was recognized that the kinetic behavior in some systems with reactions and random transport is strongly affected by many factors, which were not taken into account in previous studies. These are, to name but a few, fluctuations in the spatial distributions of the reactants and fluctuations of the reactivity, some essentially many-particle phenomena, effects of anomalous diffusion, molecular crowding, as well as the internal geometry of the reaction bath. Within recent years, along with a growing interest in chemical processes ocurring in biological systems or cellular environments, numerous advances have been made and considerable knowledge has been acquired. These seminal contributions are, however, scattered among many journals and no attempt has been made so far to present a unified picture.This book presents a general overview of different contemporary facets of chemical kinetics in a variety of different environments. It includes 23 seminal works and reviews on different aspects of reaction processes in chemical, physical and biophysical systems, both theoretical and experimental.

The book presents a comprehensive guide to the study of Lie systems from the fundamentals of differential geometry to the development of contemporary research topics. It embraces several basic topics on differential geometry and the study of geometric structures while developing known applications in the theory of Lie systems. The book also includes a brief exploration of the applications of Lie systems to superequations, discrete systems, and partial differential equations.Offering a complete overview from the topic's foundations to the present, this book is an ideal resource for Physics and Mathematics students, doctoral students and researchers.

The area of molecular imaging has matured over the past decade and is still growing rapidly. Many concepts developed for molecular biology and cellular imaging have been successfully translated to in vivo imaging of intact organisms. Molecular imaging enables the study of processes at a molecular level in their full biological context. Due to the high specificity of the molecular readouts the approach bears a high potential for diagnostics. It is fair to say that molecular imaging has become an indispensable tool for biomedical research and drug discovery and development today.This volume familiarizes the reader with the concepts of imaging and molecular imaging in particular. Basic principles of imaging technologies, reporter moieties for the various imaging modalities, and the design of targeted probes are described in the first part. The second part illustrates how these tools can be used to visualize relevant molecular events in the living organism. Topics covered include the studies of the biodistribution of reporter probes and drugs, visualization of the expression of biomolecules such as receptors and enzymes, and how imaging can be used for analyzing consequences of the interaction of a ligand or a drug with its molecular target by visualizing signal transduction, or assessing the metabolic, physiological, or structural response of the organism studied.The third edition has been extended considerably. This holds for the chapter on imaging modalities, which now includes sections on intravital microscopy and mass spectrometric imaging. All chapters have been updated and a new chapter on the challenges of translating molecular imaging solutions for clinical use has been added.

The use and practice of traditional, complementary and/or integrative medicine (TCIM) raises significant questions, poses many challenges and holds much potential for the broad fields of public health and health services research.This book brings together leading international researchers with backgrounds and expertise across broad multi-disciplinary sub-fields including health social science, biostatistics, clinical pharmacology, implementation science, health geography and health economics. Contributors draw upon their research and experience to explain and review core research and practice issues on TCIM and its future development.The book offers a rounded understanding of the current and future possibilities associated with the TCIM-public health and health services research interface and provides an essential overview of the broad evidence-base emerging in this area of research, policy and practice. Individual chapters employ specific case studies, featuring particular medicines/therapies, and focusing upon a number of health care settings and environments including general practice, community pharmacy, hospital specialisms as well as community-based private practice and self-care.

In computer science, an algorithm is an unambiguous specification of how to solve a class of problems. Algorithms can perform calculation, data processing and automated reasoning tasks.As an effective method, an algorithm can be expressed within a finite amount of space and time and in a well-defined formal language for calculating a function. Starting from an initial state and initial input (perhaps empty), the instructions describe a computation that, when executed, proceeds through a finite number of well-defined successive states, eventually producing "output" and terminating at a final ending state. The transition from one state to the next is not necessarily deterministic; some algorithms, known as randomized algorithms, incorporate random input.This book introduces a set of concepts in solving problems computationally such as Growth of Functions; Backtracking; Divide and Conquer; Greedy Algorithms; Dynamic Programming; Elementary Graph Algorithms; Minimal Spanning Tree; Single-Source Shortest Paths; All Pairs Shortest Paths; Flow Networks; Polynomial Multiplication, to ways of solving NP-Complete Problems, supported with comprehensive, and detailed problems and solutions, making it an ideal resource to those studying computer science, computer engineering and information technology.

Can the fall of globalization told through true storytelling save humanity from its own extinction? The Sixth Extinction has begun and there is no Planet B. To prevent further damage to the earth's ecosystem, this book proposes a new "Globalization Praxis" that focuses on nine planetary boundaries. This praxis is called "true storytelling". True storytelling is an ethical praxis, a methodology, and an antenarrative process of strategy.Storytelling in the Global Age provides a new approach while uncovering ten myths of globalization. Each myth explores three storytelling layers, which are: narrative–counternarrative, Indigenous Ways of Knowing (IWOK) living story, and antenarrative layers beneath. This book is useful for professionals and students within this field.

Atropisomerism and Axial Chirality provides a global survey of the chemistry of axially chiral compounds including biaryls, heterobiaryls, non-biaryl atropisomers, allenes and spyrocyclic derivatives. From the perspective of a synthetic organic chemist, this book provides a unique compilation of the available methodologies for their synthesis, with emphasis on the most efficient and modern strategies, a review of the huge amount of practical applications in the field of asymmetric catalysis, either as transition metal ligands or as organocatalysts, and an overview of their occurrence as bioactive compounds and natural products.The first of its kind, this book serves as a general introduction and a practical reference to advanced chemistry students and researchers, while also offering creative ideas for further developments in the field.

Many women scientists, particularly those who did crucial work in two world wars, have disappeared from history. Until they are written back in, the history of science will continue to remain unbalanced. This book tells the story of Elizabeth Alexander, a pioneering scientist who changed thinking in geology and radio astronomy during WWII and its aftermath.Building on an unpublished diary, recently declassified government records and archive material adding considerably to knowledge about radar developments in the Pacific in WWII, this book also contextualises Elizabeth's academic life in Singapore before the war, and the country's educational and physical reconstruction after it as it moved towards independence.This unique story is a must-read for readers interested in scientific, social and military history during the WWII, historians of geology, radar, as well as scientific biographies.

Across the world, the demands placed on health systems are growing rapidly. Developed countries face the challenge of providing services to an ageing population with changing health needs, while countries with developing health systems must find ways of ensuring their populations are provided with access to healthcare. Innovative thinking is essential to meet these twin challenges, but innovation is both a cause and cure of many struggles in healthcare - we need it, but it is hard to manage and the introduction of new technology can lead to higher costs.Using real-life examples and case studies from around the world, this book introduces the latest thinking on understanding and managing healthcare innovation more effectively. It does this from the perspective of governments responsible for shaping health policy, healthcare organisations providing services and juggling competing demands, and from the perspective of the industries that supply the new drugs, devices and other technologies.Managing Innovation in Healthcare is the perfect accompaniment for MSc, PhD and MBA students on health policy, management and public health courses, as well as managers, consultants and policy makers involved in healthcare services in both the public and private sector.

This book gives an overview of key themes domestically and internationally from the 19th Communist Party Congress held in Beijing in October 2017, setting out the main policy priorities for the Xi government in China as the country moves towards fulfillment of the first Centenary Goal, the hundredth anniversary of the Communist Party of China in 2021.Written as the first full length analysis by an international group of authors of different aspects of the Congress, making it perfect for graduate students and researchers, as well as individuals interested in China Studies.

This book is concerned with cheating in Science and the harm that it does, concentrating on three disasters in cell culture, which caused international concern and personal tragedy for the perpetrators. There is an overview of plant, animal and human cheating, providing a background to the focus on Science. This demands a special form of truth in that claims need to be substantiated by repetition in independent laboratories to confirm that the claims work. The nature of originality is examined in art and Science.An attempt has been made to determine the background and motives for cheating in Science in the certain knowledge that it will be unmasked leading to scandal.Advice is given to the young Scientist and suggestions have been made as to how fraud in Science could be reduced by more regulated supervision. There is a need to revise the regulations and assessment of claims of originality and the whole review process of journals to avoid publishing fake data.This text is unusual in focusing on three well-documented cases. The data should not have been published in high impact journals if more rigorous review had been made. Journals should require independent repetition of claims that seem to be "too good to be true". This little book should be of considerable interest to young scientists, historians of science and editors of scientific journals. The general reader might find it fascinating to learn how science works or does not work.

The book contains self-contained descriptions of existing models, accompanied by critical analyses of their properties both from a theoretical and practical standpoint. It aims to develop 'modeling skills' within the readers, giving them the ability to develop their own models and improve existing ones. Written in connection with a full, open source Python Library, this project also enables readers to run the simulations discussed within the text.

This handbook gives a general overview of the possibilities in recent developments in chromatographic retention modeling. As a result of the latest developments in modeling software, several new features are now accessible, opening a new level in HPLC method development.Many of these current possibilities in software assisted liquid chromatographic method modeling for analytical purposes are presented. Several modes of chromatography, including Reversed-Phase Liquid Chromatography (RPLC), Ion Exchange Chromatography (IEX), Hydrophobic Interaction Chromatography (HIC), and Hydrophilic Interaction Liquid Chromatography (HILIC) are explained in detail. For all these chromatographic modes, the most important variables for tuning retention and selectivity are exposed.Beside the industrial and practical benefits of retention modeling, the possibilities in teaching and education are also illustrated. Finally, numerous representative industrial examples are shown, to highlight the benefits, time and cost savings offered by state-of-the-art software assisted HPLC method development.

As an emerging discipline, data science broadly means different things across different areas. Exploring the relationship of data science with statistics, a well-established and principled data-analytic discipline, this book provides insights about commonalities in approach, and differences in emphasis.Featuring chapters from established authors in both disciplines, the book also presents a number of applications and accompanying papers.

The power of electrochemical measurements in respect of thermodynamics, kinetics and analysis is widely recognised but the subject can be unpredictable to the novice even if they have a strong physical and chemical background, especially if they wish to p