Bücher von Ravikumar Kurup

Multiple personalities all part of the primitive protoconsciousness field can exist in the same individual as alters active and competing with each other. This creates the dissociative identity disorder, demonic possession states and human disease. This can be described as akin to the ten-head of Ravana. This produces the phenomena of bhootha, pretha and pikshas which are possessive states contributing to human disease and neuropsychiatry. The human disease can be created by multiple alters related to the primitive protoconsciousness field inhabiting the universe and can be modulated by the protoconsciousness field itself by individuals who are force sensitizers. The primitive protoconsciousness field can modulate human behaviour and the past, the present and the future exist in it. This leads on to concepts of past life, predicting present life events or precognition and reincarnation. This leads on to the concept of deathlessness. This also validates astrology and human almanacs.

Panpsychism considers the universe as conscious and consciousness as a intrinsic feature of all sub-atomic particles, living things and non-living things. This gives continuity between the quantal world of existence and macroscopic world. The quantal superpositions collapse or undergo decoherance due to the observation of universal protoconsciousness field. The universal protoconsciousness field can be considered as gravity and antigravity. The universal protoconsciousness field permeates the whole galaxy and is intrinsic to all matter. Matter is a creation of consciousness.

Everything in the universe is conscious. Consciousness is a fundamental part of matter. The hypothesis was put forward by Arthur Eddington who said that we know the nature of matter that makes up the brain and that it is conscious. Therefore it follows that the matter outside the brain is aware as well. All knowledge of our environment from which the world of Physics is constituted has entered in the form of messages transmitted along the neurons to the seat of consciousness. Substrate of everything is of mental character. Mind is the first and most direct thing in our experience and all else is remote experience. The fact that all matter is conscious solves the hard problems of consciousness. Consciousness cannot arise out of unconsciousness. The Hindu idols, mantras and yagnas are alive and are force sensitizers that connect with the protoconsciousness field. This forms the basis of the Hindu mode of worship and it has its substrate in panpsychism. This can be called as avatars of protoconsciousness field.

The archaeal population densities and quasi-species RNA viroidal networks determine homo sapien/homo neanderthalis species, racial, caste, community, national, sexual, metabolic, phenotypic, immune, genotypic neuronal, psychiatric, psychological and individual identity. The homo neanderthalis would have contributed to the Kshatriya class, Vaisya class and the Sudras. The homo sapiens would have contributed to the rest of the population. The homo neanderthalis had more of endoarchaeal symbiosis and were retroviral resistant. The homo sapiens had less density of archaeal symbiosis and more of endogenous retroviral sequence in the genome. Caste and race are not fixed genetic identities but symbiotic representations. The high fibre high MCT high legume protein ketogenic diet converts the neanderthalis to sapien species and a low fibre high protein high fat diet converts the sapien species to neanderthalis species. This leads to modulation of caste, species and race.

Memes are building blocks of mind. They are also the building blocks of culture. The memes make up language and religion. The origin of speech can also be related to archaeal RNA viroidal quasi-species consortia. Speech origin can be compared to an epidemic la tourette¿s disease which consists of vocal tics, motor tics, coprolalia and obsessive compulsive disorder. It is due to post streptococcal anti glycolytic anti brain antibodies affecting the brain. The archaea and RNA viroidal modulation by extraterrestrial and terrestrial contacts with the brain and symbiosis can produce vocal tics and coprolalic words and phrases akin to la tourette¿s disease producing a primitive form of speech. The motor tics would have evolved to artistic dance and drama forms. The primitive vocal and motor tics which would have been the substratum for civilized speech would have originated as a tic syndrome consequent to extraterrestrial and terrestrial archaeal and RNA viroidal infection and symbiosis. The initial vocal and motor tics would primarily have been related to sexual content and could have contributed to a coprolalic form of speech. A sexual substratum contributed to the language evolution.

The history of India can be considered as an eternal conflict between the Neanderthalic Indo-European Aryo-Dravidians and the homo sapien Semitic African migrants to India. India was dominated by the Indo-European Aryo-Dravidian Neanderthalic groups that entered India following the breakage of the Lemurian Antarctic homeland. The Indo-European Aryo-Dravidian elite formed the caste system of Kshatriyas, Brahmins, Vaisysas and Sudras. The African migrants formed the scheduled castes and scheduled tribes and were out of the caste system. This was followed by the migration of homo sapien Semitic Muslims to India who established Muslim empires in India. The homo sapien Muslim rule in India practically exterminated fifty percentage of the Hindu Aryo-Dravidian Indo-European Neanderthalic population. This was followed by the invasion and colonization by the Neanderthalic Indo-European Aryo-Dravidian Anglo-Saxons, English, French and Dutch in India. The Indian Indo-European Aryo-Dravidian Neanderthalic Hindus were collaborative of the Indo-European Aryo-Dravidian migrants and conquerors from Europe as a form of emancipation from homo sapien Semitic Muslim rule.

Archaeal endosymbiosis leads to induction of the Warburg phenotype and increased glycolysis as well as mitochondrial dysfunction. This leads to anaerobic glycolysis and blockade of the mitochondrial oxidative phosphorylation scheme. This is indicated by low serum coenzyme Q and low serum ATP. An endosymbiotic archaeal mediated mitochondrial disease is described. The archaeal digoxin inhibits membrane sodium potassium ATPase and induces membrane sodium potassium ATPase mediated ATP synthesis. The endosymbiotic archaea induced mitochondrial disease has been related to the pathogenesis of schizophrenia, malignancy, metabolic syndrome X, autoimmune disease and neuronal degeneration.

Actinidic archaea have been implicated in the pathogenesis of schizophrenia, malignancy, metabolic syndrome X, autoimmune disease and neuronal degeneration.1-9 Actinide based primitive organism like archaea have a mevalonate pathway and cholesterol catabolism. Cholesterol catabolism by actinidic archaea can lead to cholesterol depletion and a hypocholesterolemic state contributing to the pathogenesis of these disorders. Archaeal endosymbiosis leads to archaeal cholesterol oxidation for its energetics. The cholesterol ring is oxidized to generate pyruvate while the side chain is oxidized to generate short chain fatty acids and bile acids. The cholesterol oxidation by archaea leads to a cholesterol depletion syndrome and disease phenotype. Archaea can use cholesterol as a carbon and energy source. Archaeal cholesterol catabolism can lead to multiple systemic disease. Low cholesterol values in populations have been related to high mortality. This can be described as the endosymbiotic actinidic archaeal cholesterol catabolic syndrome.

Archaeal endosymbiosis leads to increased porphyrin synthesis leading on to porphyrinuria and porphyria. The stimulus for porphyrin synthesis comes from heme deficiency. Heme suppresses ALA synthase. Stress induces heme oxygenase which converts heme to carbon monoxide and bilirubin. Thus heme is depleted from the system. Thus there is increased porphyrin synthesis from succinyl CoA and glycine. The increase in porphyrins leads to cortical dysfunction and prefrontal cortex atrophy. The porphyrins can destroy the human endogenous retroviruses and the jumping genes leading to lack of dynamicity of the genome. This leads on to maldevelopment of the prefrontal cortex. This leads on to cerebellar dominance and a cerebellar cognitive affective disorder. This produces porphyrin related quantal perception. This leads on to neanderthalisation of the brain and schizophrenia and autism.

Archaeal endosymbiosis leads to induction of the Warburg phenotype and increased glycolysis as well as mitochondrial dysfunction. The pyruvate generated consequent to the glycolytic cascade enters the GABA shunt where it is converted to glutamate, GABA and succinyl CoA. The pyruvate is converted to glutamate which gets acted upon by glutamate dehydrogenase generating ammonia. The endosymbiotic archaea can oxidize ammonia for its energetics. Archaeal cholesterol catabolism mediated by archaeal cholesterol oxidase can also produce cholesterol ring oxidation to generate pyruvate. Pyruvate is converted to glutamate by the enzyme serum glutamate pyruvate transaminase. The glutamate gets acted upon by glutamate dehydrogenase to generate ammonia. Archaeal urease can act upon urea generating ammonia and thiocyanate. The archaea are ammonia oxidizing and can use ammonia for their energetics. The archaeal urease activity related ammonia and thiocyanate synthesis as well as cholesterol oxidase activity generating pyruvate and ammonia are important schizophrenia, malignancy, metabolic syndrome X, autoimmune disease and neuronal degeneration.

Archaeal endosymbiosis leads to selenium deficiency. The archaea uses selenium to synthesize archaeal selenoproteins. This leads to cellular selenium deficiency. Selenium deficiency leads to defective retroviral propagation as the retroviruses contain selenoprotein sequences and need selenium to synthesize them. Selenium deficiency leads to defective glutathione synthetase and glutathione peroxidase dysfunction leading to free radical stress and neurodegeneration, cancer, autoimmune disease and metabolic syndrome. Selenium deficiency leads to defective T4 to T3 conversion as deiodinase needs selenium as a cofactor. Selenium deficiency leads to hypothyroidism and Hashimotös thyroiditis. Selenium deficiency leads to cardiomyopathy and pancreatitis. Hashimotös thyroiditis consequent to selenium deficiency is associated with cerebral small vessel disease, normal pressure hydrocephalus, Hashimotös encephalopathy, non-vasculitic autoimmune meningitis, autoimmune dementia and recurrent hyponatraemic encephalopathy. Selenium deficiency leads to an endocrine cardiac syndrome and a neurological syndrome.

Global warming can lead to osmotic stress consequent to dehydration. The increase in actinidic archaeal growth leads to cholesterol catabolism and digoxin synthesis. Digoxin produces membrane sodium potassium ATPase inhibition and increase in intracellular calcium producing mitochondrial dysfunction. This results in oxidative stress. The oxidative stress and osmotic stress can induce the enzyme aldose reductase which converts glucose to fructose. Fructose has got a low km value for ketokinase as compared to glucose. Therefore fructose gets phosphorylated more to fructose phosphate and the cell is depleted of ATP. The fructose phosphate can enter the glucosamine pathway synthesizing glycosaminoglycans and producing mucopolysaccharide accumulation. This can lead to the global warming related mucopolysaccharidosis syndrome of endomyocardial fibrosis, chronic calcific pancreatitis, multinodular goitre and mucoid angiopathy.

Archaeal endosymbiosis leads to increased porphyrin synthesis resulting in channeling of glycine to porphyrin synthesis. There is no conversion of glycine to serine which is used for cystathionine synthesis. Homocysteine is converted to methionine and back by the methylation/demethylation pathway. The homocysteine in its forward metabolism combines with serine to generate cystathionine which is further metabolized to cysteine by cystathioninase. The lack of serine due to increased utilization for porphyrin synthesis leads to defective cystathionine synthesis and accumulation of homocysteine producing homocysteinemina. The homocysteine gets converted to methionine. Methionine donates methyl groups for the methylation of biogenic amines like epinephrine, norepinephrine, dopamine and serotonin as well as their metabolites. This leads to the generation of methylated amines like 3,4-dimethoxyphenylethylamine, LSD, mescaline and N-methyltryptamine. These are generated by N-methylation and O-methylation of biogenic amines and are hallucinogenic leading to disorders of consciousness like schizophrenia, mood disorders and autism.

The climate change results in endosymbiotic actinidic archaeal growth in the human system and cholesterol catabolism resulting in endogenous digoxin synthesis. The endosymbiotic archaea catabolize cholesterol for its energetics and synthesizes digoxin. Digoxin functions as an endogenous sodium potassium ATPase inhibitor and neuro-immuno-endocrine integrator. The increased endosymbiotic archaeal growth and resultant endogenous digoxin synthesis in relation to climate change results in neanderthalisation of homo sapiens and human disease. Digoxin can inhibit reverse transcriptase activity and RNA editing resulting in suppression of endogenous retroviral growth. This produces inhibition of HERV expression and jumping gene phenomena producing in adynamicity of the human genome. The digoxin interference with HERV expression and RNA editing and resultant inhibition of genomic, metabolic, neural and immune diversity produces autoimmune disease, cancer, metabolic syndrome, degenerations, schizophrenia and autism. A new endosymbiotic archaea related hypodigoxinemic and hyperdigoxinemic syndrome is described.

The homo neanderthalis had increased actinidic archaeal growth and archaeal magnetite/porphyrin mediated quantal perception. This gave a feeling of collective unconscious and universal oneness. The homo sapiens had decreased actinidic archaeal growth and archaeal magnetite/porphyrin mediated quantal perception was minimal. This is the biological basis of the features of homo neanderthalis society- primitive communism, socialism, democracy, female dominance, alternate sexuality, creativity in art and literature, spirituality, eco-consciousness, peaceful co-existence and a globalised world. The homo sapien society was selfish, primitive capitalistic, undemocratic, dictatorial, patriarchal, more masculine, less creative in art and literature, non-spiritual and material, heterosexual, exploitative, polluting, nationalistic and with an increased propensity to war. . The high fibre high MCT high legume protein ketogenic diet converts the neanderthalis to sapien species and a low fibre high protein high fat diet converts the sapien species to neanderthalis species. This leads to modulation of economic and political systems.

The homo neanderthalic have increased endosymbiotic archaeal growth and quantal perception leading to a cerebellar cognitive affective disorder. The cerebellum is the site of impulsive behaviour and the unconscious behaviour. The cerebellar and subcortical brain connections are predominantly archaeal colony networks. The idea of evil is related to hell. The idea of conscious judgmental acts and unconscious impulsive acts, heaven and hell, goodness and evil are juxtapositions. This leads to increased spirituality in homo neanderthalis. The homo sapiens with low endosymbiotic brain archaeal growth and quantal perception has lesser spirituality. The high fibre high MCT high legume protein ketogenic diet converts the neanderthalis to sapien species and a low fibre high protein high fat diet converts the sapien species to neanderthalis species. This leads to modulation of spirituality.

Actinidic archaea has been related to global warming and human diseases especially autoimmune diseases like systemic lupus erythematosis, multiple sclerosis and rheumatoid arthritis. The growth of endosymbiotic actinidic archaea in relation to climate change and global warming leads to neanderthalisation of the human mind-body system. Digoxin produced by archaeal cholesterol catabolism produces neanderthalisation. Prefrontal cortical atrophy and cerebellar hyperplasia has been related to autoimmune diseases like systemic lupus erythematosis, multiple sclerosis and rheumatoid arthritis. This leads on to dysautonomia with sympathetic hyperactivity and parasympathetic neuropathy in these disorders. Actinidic archaeal related cerebellar dominance leads to changes in brain function and immune activation. This leads to systemic lupus erythematosis, multiple sclerosis and rheumatoid arthritis. The high fibre high MCT high legume protein ketogenic diet converts the neanderthalis to sapien species and a low fibre high protein high fat diet converts the sapien species to neanderthalis species. This leads to modulation of autoimmunity.

Actinidic archaea has been related to global warming and human diseases especially metabolic syndrome X. The growth of endosymbiotic actinidic archaea in relation to climate change and global warming leads to neanderthalisation of the human mind-body system. Neanderthal metabolonomics has been described in metabolic syndrome X especially the Warburg phenotype and hyperdigoxinemia. Digoxin produced by archaeal cholesterol catabolism produces neanderthalisation. Prefrontal cortical atrophy and cerebellar hyperplasia has been related to neurodegeneration and neuropsychiatric disorder. This leads on to dysautonomia with sympathetic hyperactivity and parasympathetic neuropathy in these disorders. Actinidic archaeal related cerebellar dominance leads to changes in metabolic and endocrine function. The high fibre high MCT high legume protein ketogenic diet converts the neanderthalis to sapien species and a low fibre high protein high fat diet converts the sapien species to neanderthalis species. This leads to modulation of metabolic and endocrine function.

Neanderthal genes have been described in the homo sapien population. The Neanderthal brain structure results in female dominance and matriarchal social patterns. It was considered plausible that Neanderthal genomics and metabolonomics could also contribute to androgynous behaviour. It has been demonstrated that Neanderthal phenotype is due to symbiosis by actinidic archaea using cholesterol as an energy substrate. Cholesterol is also converted to steroidogenic estrogens and testosterone. The increasing growth of actinidic archaea converts the body metabolites the cholesterol which is subsequently oxidized and depleted. This results in sex hormone deficiency and evolution of asexual and alternate sexual phenotypes. The high fibre high MCT high legume protein ketogenic diet converts the neanderthalis to sapien species and a low fibre high protein high fat diet converts the sapien species to neanderthalis species. This leads to modulation of sexuality.

Lamarckian hereditability of acquired characteristics proposed natural cooperation as opposed to natural selection. The endosymbiotic archaea secrete RNA viroids. The archaeal RNA viroids are converted to DNA viroids by endogenous HERV reverse transcriptase and integrated into the genome by HERV integrase. Archaeal endosymbiosis can occur consequent to global warming, stress, dietary fibre deficiency and exposure to low level EMF which leads to increased colonic archaeal growth and endosymbiosis. The archaea will secrete RNA viroids which can get converted to DNA viroids and get integrated into the genome functioning as jumping genes modulating gene expression. The RNA viroids and their DNA templates getting integrated into the genome consequent to environmental stress leads to genomic flexibility and dynamicity which can be inherited. Exposure to environmental stress can alter the genome changing body function in response to stress and genomic change which is acquired is hereditable. Symbiotic genomics forms the basis of global anarchic culture ¿ the tribe of urban nomadic, anarcho-capitalistic, androgynous pagans.

Lamarckian hereditability of acquired characteristics proposed natural cooperation as opposed to natural selection. The endosymbiotic archaea secrete RNA viroids. The archaeal RNA viroids are converted to DNA viroids by endogenous HERV reverse transcriptase and integrated into the genome by HERV integrase. Archaeal endosymbiosis can occur consequent to global warming, stress, dietary fibre deficiency and exposure to low level EMF which leads to increased colonic archaeal growth and endosymbiosis. The archaea will secrete RNA viroids which can get converted to DNA viroids and get integrated into the genome functioning as jumping genes modulating gene expression. The RNA viroids and their DNA templates getting integrated into the genome consequent to environmental stress leads to genomic flexibility and dynamicity which can be inherited. Exposure to environmental stress can alter the genome changing body function in response to stress and genomic change which is acquired is hereditable. Symbiotic genomics forms the basis of Brain Function, Immunity, Metabolic Integration and Cell Cycle Changes ¿ the Generation of Disease Phenotype.

Lamarckian hereditability of acquired characteristics proposed natural cooperation as opposed to natural selection. The endosymbiotic archaea secrete RNA viroids. The archaeal RNA viroids are converted to DNA viroids by endogenous HERV reverse transcriptase and integrated into the genome by HERV integrase. Archaeal endosymbiosis can occur consequent to global warming, stress, dietary fibre deficiency and exposure to low level EMF which leads to increased colonic archaeal growth and endosymbiosis. The archaea will secrete RNA viroids which can get converted to DNA viroids and get integrated into the genome functioning as jumping genes modulating gene expression. The RNA viroids and their DNA templates getting integrated into the genome consequent to environmental stress leads to genomic flexibility and dynamicity which can be inherited. Exposure to environmental stress can alter the genome changing body function in response to stress and genomic change which is acquired is hereditable. Symbiotic genomics forms the basis of species, caste and race.

Climate change, global warming and archaeal endosymbiosis leads to neanderthalisation of the human brain. The archaeal magnetite and porphyrions are capable of quantal perception and leads to a cerebellar cognitive affective disorder consequent to cerebral cortical atrophy and cerebellar dominance. This leads to impulsive behaviour, violent behaviour, terrorist acts which leads to surrealistic state and transcendence. The Yellow-vest movement dominating France and spreading to other parts of Europe and the world signifies this brain change consequent to archaeal endosymbiosis and brain neanderthalisation. The quantal perception of the neanderthalised brain leads to a sense of spirituality and collective consciousness among individual groups. The Yellow-vest movement is a merger of the far-right and far-left of the European political spectrum. The movement represents a type of global anarchy and is leaderless and is a form of democratic protest based on grass-root network and bottom up organisation of the socio-political movement.

Meditation can modulate body metabolonomics and brain function. Internet addiction also is akin to a meditative exercise with focused obsessed attention. The mechanism is by induction of the heme oxygenase system. Heme oxygenase induction suppresses ALA synthase. Thus heme is depleted from the system. There is increased porphyrin synthesis leading onto porphyrinuria and porphyria. The stimulus for porphyrin synthesis comes from heme deficiency. Porphyrins can organize into self replicating supramolecular structures called porphyrions which are induced by meditative practices. The porphyrins can self organise to form macromolecular structures which can self replicate to form a porphyrin organism. The photon induced transfer of electrons along the macromolecule can lead to light induced ATP synthesis. The porphyrins can form a template on which RNA and DNA can form generating viroids. The porphyrins can also form a template on which prions can form. They all can join together ¿ RNA viroids, DNA viroids, prions ¿ to form primitive archaea. Archaeal endosymbiosis leads to species change and neanderthalisation producing a quantal perceptive brain in contact with universal consciousness.

Internet addiction leads to exposure to low level of EMF fields which promotes endosymbiotic and colonic archaeal growth. The endosymbiotic and colonic archaeal growth leads to methanogenesis and global warming. Exposure to low level of electromagnetic fields of the internet induces the enzyme heme oxygenase in the brain. The deficiency of heme leads to induction of ALA synthase and porphyrin synthesis. Porphyrins can self organise to form supramolecular structures called as porphyrions. The porphyrions can store information, can self replicate and can have its own energetics generated by light related electron transport generating ATP. The porphyrions are the simplest self replicating organisms that are known. The porphyrions can form a template for the generation of RNA viroids, DNA viroids, prions and isoprenoid organism. These RNA viroids, DNA viroids, prions and isoprenoid organism can self organise to form magnetotactic nanoarchaea. This forms a vicious cycle leading to increased brain endosymbiotic archaeal growth capable of quantal perception and perception of internet fields. This leads to a new homo neanderthalis species.

Modern civilization results in changes in dietary habits leading to less consumption of fibre and more intake of protein and fat. This leads to increased colonic archaeal growth and archaeal endosymbiosis. Modern civilization results in stress in societies leading to increased activation of the HPA axis leading to increased secretion of stress hormones the catecholamines producing increase in sympathetic tone. The increase in sympathetic tone leads to increase in stress hormones epinephrine and norepinephrine producing breeching of the gut blood barrier. This leads to decrease in mucin secretion lining the gut wall and inflammatory changes in the colonic mucosa. This leads to increase in archaeal growth and colonic archaeal translocation into to the blood and tissues producing archaeal endosymbiosis. Endosymbiotic archaea generates RNA viroids which gets converted to DNA viroids by endogenous retroviral reverse transcriptase and gets integrated into the genome by integrase. The endosymbiotic archaea by inducing the Warburg phenotype can increase lymphocytic glycolysis and produce chronic immune activation. Thus archaeal endosymbiosis results in a new immune phenotype.

Modern civilization results in changes in dietary habits leading to less consumption of fibre and more intake of protein and fat. This leads to increased colonic archaeal growth and archaeal endosymbiosis. Modern civilization results in stress in societies leading to increased activation of the HPA axis leading to increased secretion of stress hormones the catecholamines producing increase in sympathetic tone. The increase in sympathetic tone leads to increase in stress hormones epinephrine and norepinephrine producing breeching of the gut blood barrier. This leads to decrease in mucin secretion lining the gut wall and inflammatory changes in the colonic mucosa. This leads to increase in archaeal growth and colonic archaeal translocation into to the blood and tissues producing archaeal endosymbiosis. Endosymbiotic archaea generates RNA viroids which gets converted to DNA viroids by endogenous retroviral reverse transcriptase and gets integrated into the genome by integrase. The endosymbiotic archaea functions as cellular organelle called archaeaons which can function as neurotransminoids, fructosoids, steroidelle, viroidelle and vitaminocyte. The archaeaons change cell structure.

Modern civilization results in changes in dietary habits leading to less consumption of fibre and more intake of protein and fat. This leads to increased colonic archaeal growth and archaeal endosymbiosis. Modern civilization results in stress in societies leading to increased activation of the HPA axis leading to increased secretion of stress hormones the catecholamines producing increase in sympathetic tone. The increase in sympathetic tone leads to increase in stress hormones epinephrine and norepinephrine producing breeching of the gut blood barrier. This leads to decrease in mucin secretion lining the gut wall and inflammatory changes in the colonic mucosa. This leads to increase in archaeal growth and colonic archaeal translocation into to the blood and tissues producing archaeal endosymbiosis. Endosymbiotic archaeal growth which has got magnetoperception and quantal perception of low level of EMF. This leads to frontal cortical atrophy and cerebellar dominance. There is an endemic cerebellar cognitive affective disorder presenting as adult onset autism, impulsive behaviour, violence, introversion, solitude and aggression. This produces a mind change.

Modern civilization results in changes in dietary habits leading to less consumption of fibre and more intake of protein and fat. This leads to increased colonic archaeal growth and archaeal endosymbiosis. Modern civilization results in stress in societies leading to increased activation of the HPA axis leading to increased secretion of stress hormones the catecholamines producing increase in sympathetic tone. The increase in sympathetic tone leads to increase in stress hormones epinephrine and norepinephrine producing breeching of the gut blood barrier. This leads to decrease in mucin secretion lining the gut wall and inflammatory changes in the colonic mucosa. This leads to increase in archaeal growth and colonic archaeal translocation into to the blood and tissues producing archaeal endosymbiosis. Endosymbiotic archaea generates RNA viroids which gets converted to DNA viroids by endogenous retroviral reverse transcriptase and gets integrated into the genome by integrase. The endosymbiotic archaea can induce the Warburg phenotype by upregulating glycolysis and inhibiting mitochondrial function producing a new metabolic and endocrine phenotype.