Clinical Applications of Immunotoxins

PASTAN , and J. ROBERTUS Introduction . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 3 3 Intracellular Processing - Cleavage and Reduction . . . . . . 1 Cytosolic Activity . . . , diphtheria toxin, Pseudomonas exotoxin and ricin) are among the most toxic substances known.