Molecular Neurosurgery with Targeted Toxins

Gives a treatment of the highly successful use of the 192 IgG-saporin and ME20.4-saporin immunotoxins to lesion the cholinergic basal forebrain in order to model the behavior, anatomy, physiology, and pharmacology of Alzheimer's disease in animals. This book explains the theory and techniques of using targeted toxins experimentally.