Quercetin and chemotherapeutic complications

Adriamycin (ADR) is a chemotherapeutic drug widely used for the treatment of cancerous diseases. Its use is limited, due to its toxic action on healthy tissues. Recently, flavonoids (such as quercetin) have been shown to have potent antioxidant properties for improving the body's detoxifying status and immune response to infectious agents. Thus, the present book discusses the effects of acute exposure to a medium dose of ADR on the biochemical, hematological and histopathological aspects of male Wistar rats, and the ability of quercetin to restore ADR-induced disturbances.